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Name : NMA1620 (NMA1620) Accession : YP_002342925.1 Strain : Neisseria meningitidis Z2491 Genome accession: NC_003116 Putative virulence/resistance : Virulence Product : cytolysin secretion ABC transporter Function : - COG functional category : V : Defense mechanisms COG ID : COG2274 EC number : - Position : 1523857 - 1526085 bp Length : 2229 bp Strand : - Note : NMA1620, probable cytolysin secretion ABC transporter, len: 742aa; similar to many involved in cytolysin secretion eg. SW:P26760 (RT1B_ACTPL) RTX-1 toxin secretion ATP-binding protein from Actinobacillus pleuropneumoniae (Haemophilus pleuropneumoniae) (70 DNA sequence : ATGCGTTCTGCTGTTTTATTTATATATTTCTTTCTACTTAATATATTCCTTTTCCAGCCAGCCGTTATCCACATCCAATC TAACTATATTTTATTTATGTCTATCGTATCCGCACCGCTCCCCGCCCTTTCCGCCCTCATCATCCTCGCCCATTACCACG GCATTGCCGCCAATCCTGCCGATATACAGCATGAATTTTGTACTTCCGCACAGAGCGATTTAAATGAAACGCAATGGCTG TTAGCCGCCAAATCTTTGGGATTGAAGGCAAAGGTAGTCCGCCAGCCTATTAAACGTTTGGCTATGGCGACTTTACCCGC ATTGGTATGGTGTGATGACGGCAACCATTTTATTTTGGCTAAAACAGACGGTGGGGGTGAGCATGCCCAATATCTAATAC AGGATTTAACTACGAATAAGTCTGCGGTATTGTCTTTTGCCGAATTTTCTAACAGATATTCGGGCAAACTGATATTGGTT GCTTCCCGCGCTTCGGTATTGGGCAGTTTGGCAAAGTTTGACTTTACCTGGTTTATTCCGGCGGTAATCAAATACCGCCG GTTGTTTTTTGAAGTATTGGTGGTGTCGGTGGTGTTGCAGCTGTTTGCGCTGATTACGCCTCTGTTTTTCCAAGTGGTGA TGGACAAGGTGCTGGTACATCGGGGATTCTCTACTTTGGATGTGGTGTCGGTGGCTTTGTTGGTGGTGTCGCTGTTTGAG ATTGTGTTGGGCGGTTTGCGGACGTATCTGTTTGCACATACGACTTCACGTATTGATGTGGAATTGGGCGCGCGTTTGTT CCGGCATCTGCTTTCCCTGCCTTTATCCTATTTCGAGCACAGACGAGTGGGTGATACGGTGGCTCGGGTGCGGGAATTGG AGCAGATTCGCAATTTCTTGACCGGTCAGGCGCTGACTTCGGTGTTGGATTTGGCGTTTTCGTTTATCTTTCTGGCGGTG ATGTGGTATTACAGCTCCACTCTGACTTGGGTGGTATTGGCTTCGTTGCCTGCCTATGCGTTTTGGTCGGCATTTATCAG TCCGATACTGCGGACGCGTCTGAACGATAAGTTCGCGCGCAATGCAGACAACCAGTCGTTTTTAGTAGAAAGCATCACTG CGGTGGGTACGGTAAAGGCGATGGCGGTGGAGCCGCAGATGACGCAGCGTTGGGACAATCAGTTGGCGGCTTATGTGGCT TCGGGATTTCGGGTAACGAAGTTGGCGGTGGTCGGCCAGCAGGGGGTGCAGCTGATTCAGAAGCTGGTGACGGTGGCGAC GTTGTGGATTGGCGCACGGCTGGTAATTGAGAGCAAGCTGACGGTGGGGCAGCTGATTGCGTTTAATATGCTCTCGGGAC AGGTGGCGGCGCCTGTTATCCGTTTGGCGCAGTTGTGGCAGGATTTCCAGCAGGTGGGGATTTCGGTGGCGCGTTTGGGG GATATTCTGAATGCGCCGACCGAGAATGCGTCTTCGCATTTGGCTTTGCCCGATATCCGGGGGGAGATTACGTTCGAACA TGTCGATTTCCGCTATAAGGCGGACGGCAGGCTGATTTTGCAGGATTTGAACCTGCGGATTCGGGCGGGGGAAGTGCTGG GGATTGTGGGACGTTCGGGGTCGGGCAAATCCACACTCACCAAATTGGTGCAGCGTCTGTATGTACCGGCGCAGGGACGG GTGTTGGTGGACGGCAACGATTTGGCTTTGGCCGCTCCTGCTTGGCTGCGGCGGCAGGTCGGCGTGGTCTTGCAGGAGAA TGTGCTGCTCAACCGCAGCATACGCGACAATATCGCGCTGACGGATACGGGTATGCCGCTGGAACGCATTATCGAAGCAG CCAAACTGGCGGGCGCACACGAGTTTATTATGGAGCTGCCGGAAGGCTACGGCACCGTGGTGGGCGAACAAGGGGCCGGC TTGTCGGGCGGACAGCGGCAGCGTATTGCGATTGCCCGCGCGTTAATCACCAATCCGCGCATTCTGATTTTTGATGAAGC CACCAGCGCGCTGGATTATGAAAGTGAACGAGCGATTATGCAGAACATGCAGGCCATTTGCGCCAACCGGACGGTGCTGA TTATCGCCCACCGTCTGTCCACTGTTAAAACGGCACACCGGATCATTGCCATGGATAAAGGCAGGATTGTGGAAGCGGGA ACACAGCAGGAATTGCTGGCGAAGCCGAACGGATATTACCGCTATCTGTATGATTTACAGAACGGGTAG Protein sequence : MRSAVLFIYFFLLNIFLFQPAVIHIQSNYILFMSIVSAPLPALSALIILAHYHGIAANPADIQHEFCTSAQSDLNETQWL LAAKSLGLKAKVVRQPIKRLAMATLPALVWCDDGNHFILAKTDGGGEHAQYLIQDLTTNKSAVLSFAEFSNRYSGKLILV ASRASVLGSLAKFDFTWFIPAVIKYRRLFFEVLVVSVVLQLFALITPLFFQVVMDKVLVHRGFSTLDVVSVALLVVSLFE IVLGGLRTYLFAHTTSRIDVELGARLFRHLLSLPLSYFEHRRVGDTVARVRELEQIRNFLTGQALTSVLDLAFSFIFLAV MWYYSSTLTWVVLASLPAYAFWSAFISPILRTRLNDKFARNADNQSFLVESITAVGTVKAMAVEPQMTQRWDNQLAAYVA SGFRVTKLAVVGQQGVQLIQKLVTVATLWIGARLVIESKLTVGQLIAFNMLSGQVAAPVIRLAQLWQDFQQVGISVARLG DILNAPTENASSHLALPDIRGEITFEHVDFRYKADGRLILQDLNLRIRAGEVLGIVGRSGSGKSTLTKLVQRLYVPAQGR VLVDGNDLALAAPAWLRRQVGVVLQENVLLNRSIRDNIALTDTGMPLERIIEAAKLAGAHEFIMELPEGYGTVVGEQGAG LSGGQRQRIAIARALITNPRILIFDEATSALDYESERAIMQNMQAICANRTVLIIAHRLSTVKTAHRIIAMDKGRIVEAG TQQELLAKPNGYYRYLYDLQNG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hlyB | NP_755448.1 | hemolysin B | Virulence | PAI I CFT073 | Protein | 0.0 | 70 |
| hlyB | CAD33760.1 | hemolysin B | Virulence | PAI I 536 | Protein | 0.0 | 70 |
| hlyB | CAD42038.1 | HlyB protein | Virulence | PAI II 536 | Protein | 0.0 | 70 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| NMA1620 | YP_002342925.1 | cytolysin secretion ABC transporter | VFG0907 | Protein | 0.0 | 70 |
| NMA1620 | YP_002342925.1 | cytolysin secretion ABC transporter | VFG1557 | Protein | 0.0 | 70 |
| NMA1620 | YP_002342925.1 | cytolysin secretion ABC transporter | VFG1501 | Protein | 0.0 | 70 |
| NMA1620 | YP_002342925.1 | cytolysin secretion ABC transporter | VFG0841 | Protein | 0.0 | 66 |
| NMA1620 | YP_002342925.1 | cytolysin secretion ABC transporter | VFG1269 | Protein | 5e-175 | 56 |
