Gene Information

Name : pyk (VV1_0644)
Accession : NP_759629.1
Strain :
Genome accession: NC_004459
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 661983 - 663395 bp
Length : 1413 bp
Strand : +
Note : COG0469

DNA sequence : 
ATGAAAAAGACCAAAATCGTATGTACGATTGGCCCAAAAACTGAGTCTGTAGAGAAACTGACTGAACTAGTCAACTCAGG
TATGAACGTAATGCGCCTGAACTTTTCTCACGGTGACTACGTAGAGCACGGCACTCGTATCGCGAACTTCCGCCAAGTAA
TGGAAAACACAGGTAAGCAACTTGCTATCTTACTAGACACTAAAGGTCCAGAAATCCGCACTATCAAACTAGAAAACGGC
GACGACGTTGATCTAGTAGCTGGTCAAGAATTCACTTTCACGACTGATACTTCTGTTGTTGGTAACAAAGACATCGTAGC
AGTAACTTACCCAGGTTTTGCTGCGGATCTATCTGCTGGTAACACTATCCTAGTTGACGATGGTCTAATCGAGATGGAAG
TTATCGCAACGACTGCGACTGAAGTTAAGTGTAAAGTACTGAACAACGGTGCTCTAGGCGAAAACAAAGGTGTTAACCTA
CCAGGCGTTTCTGTAAACCTACCTGCACTATCTGAAAAAGACAAAAACGACCTTAAATTTGGTTGTGAGCAAGGCGTTGA
CTTCGTTGCAGCATCTTTCATCCGTAAAGCATCTGACGTAAAAGAAATCCGTGAAGTTCTAGCAGCAAACGGCGGCGCGA
ACATTCAGATCATTTCTAAGATTGAAAACCAAGAAGGTGTTGATAACTTCGACGAAATCCTAGAGCTTTCTGACGGTATC
ATGGTTGCTCGTGGTGACCTAGGTGTAGAAATCCCTGCAGAAGAAGTTATCTTCGCACAGAAGATGATGATCGAAAAATG
TAACCGCGCACGTAAAGTGGTTATCACTGCAACTCAAATGCTAGATTCTATGATCAAGAACCCACGTCCAACTCGTGCTG
AAGCGGGTGACGTTGCGAACGCAATCATGGATGGTACTGATGCAGTCATGCTTTCTGGCGAAACAGCGAAAGGTAAATAC
CCTGTTGAAGCGGTAACTATCATGGCGCAAATCGCTAACCGTACTGATTCTGTACTAAAAGCAGAGCTAGGCTCTCGTCT
AGACAGCCCACGCCTACGTATCACTGAAGCGGTATGTAAAGGTGCAGTAGACACAGCTGAGAAACTAGCAGCACCACTGA
TCATCGTTGCAACTGAAGGTGGTAAGTCTGCACGCTCTGTACGTAAGTACTTCCCAACTGCAAACATTCTTGCGCTAACG
ACGAACAAGAAGACAGCAGCTCAACTTGTACTGACTAAAGGTGTTACACCTGTTGTTGTTGATTCAATCGACAACACGGA
TGCGTTCTACGTAACCGGTAAAGAGCTTGCTCTTGAATCTGGCCTAGGTAGCAAAGGCGACATCGTTGTGATGGTATCTG
GTGCTCTTGTTGCATCTGGTACAACGAATACTGCGTCAGTACACGTACTATAA

Protein sequence : 
MKKTKIVCTIGPKTESVEKLTELVNSGMNVMRLNFSHGDYVEHGTRIANFRQVMENTGKQLAILLDTKGPEIRTIKLENG
DDVDLVAGQEFTFTTDTSVVGNKDIVAVTYPGFAADLSAGNTILVDDGLIEMEVIATTATEVKCKVLNNGALGENKGVNL
PGVSVNLPALSEKDKNDLKFGCEQGVDFVAASFIRKASDVKEIREVLAANGGANIQIISKIENQEGVDNFDEILELSDGI
MVARGDLGVEIPAEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAIMDGTDAVMLSGETAKGKY
PVEAVTIMAQIANRTDSVLKAELGSRLDSPRLRITEAVCKGAVDTAEKLAAPLIIVATEGGKSARSVRKYFPTANILALT
TNKKTAAQLVLTKGVTPVVVDSIDNTDAFYVTGKELALESGLGSKGDIVVMVSGALVASGTTNTASVHVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-177 79
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-177 79
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-177 79
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-176 78

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk NP_759629.1 pyruvate kinase VFG0479 Protein 1e-177 79