Gene Information

Name : VP2039 (VP2039)
Accession : NP_798418.1
Strain :
Genome accession: NC_004603
Putative virulence/resistance : Virulence
Product : pyruvate kinase II
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 2140192 - 2141634 bp
Length : 1443 bp
Strand : +
Note : similar to GB:AAF95156.1 (AE004275) percent identity 75 in 480 aa

DNA sequence : 
ATGACTTCCAAATTAAGAAGAACGAAAATTGTCACCACTCTTGGCCCTTCAACTGATAAAGACAATGTACTGGAGGAAAT
CATTAAAGCTGGAGCGAACGTCGTTCGTATGAACTTTTCTCACGGTACAAGTGAAGACCACATTCAACGCGCTAAAAAAG
TACGCGCGATTGCCGCAAGATTAGGGCGTCAGGTTGCCATTCTTGGCGATTTACAGGGACCTAAAATTCGTGTTTCGACC
TTTAAAGACGGTAAAATCACACTCAAAGTCGGCGATAAATTCACACTAGATAGCGACTTACCAAAAGGCGAAGGGAACCA
AGAATCCGTTGGTTTGGATTACAAAGAACTGCCTCAAGATGTTTCACCGAACGACATTCTACTGCTTGATGATGGCAGAG
TTCAATTGCAAGTCACCAGCGTAGAAGGAAATAAAGTCCATACCCGTGTGACCGTTGGTGGCCCATTATCCAATAACAAG
GGCATCAACAAAAAAGGCGGTGGCTTATCAGCCGATGCACTCACGGAAAAAGACAAAGCTGACATAATCACAGCCGCAGA
AATTAAGGTCGACTATTTGGCCATTTCTTTCCCACGCAATGGCGAGGACATGCACTATGCCAGACGCTTGGCCCGGGATG
CCGGCTTAGAAGCAAAACTCGTCGCAAAAGTAGAACGTGCAGAAACCGTCGCCACGAGCGAGTCGATTGACGATATCATC
CTAGCTTCTGACGTCGTGATGGTCGCTCGCGGCGATTTAGGCGTTGAGATTGGCGATCCTGAGCTGATCGGTGTTCAGAA
AAAACTCATTCGTCGAGCTCGCAGTTTGAACCGCGTCGTCATTACTGCAACTCAAATGATGGAATCCATGATCAATAGCC
CAATGCCAACGCGTGCAGAAGTCATGGACGTAGCAAACGCCGTTTTGGATGGCACCGATGCCGTGATGCTGTCTGGAGAG
ACCGCTGCCGGTCAATATCCGGTAGAGACCGTGAAATCAATGGCGGATGTCTGTATTGGCGCAGAAAAGATGTCTGAAGC
AAGTCTATCGACCTACCGTCTCGACCGCACCTTTGAAACAGCAGAAGAGACCATTGCAATGGCAACCATGTACTCAGCGA
ATCACATGGAAGGCATTAAAGCGATGATTGCATTAACAGAGTCAGGAAGAACAGCTTTGATGATGTCACGCCTAAGCTCT
GGTTTGCCGATTTTTGCTTTATCGCGTAACGAATCGACGCTCAACCGCGCAGCGTTATATCGTGGCGTGACGCCAGTGTA
CTTTGATGCGAAATGCGATGCGGGCTTACCAACCGCTCAAGCCGCAATTTCTAGCCTCAAAGATCAAGGTTACTTACATG
AAGGTGACTTAGTGATCATCACTCAAGGTGACGTGATGGACGTCGTTGGTTCAACCAACTGCATGCGTATTCTGCCAGTC
TAA

Protein sequence : 
MTSKLRRTKIVTTLGPSTDKDNVLEEIIKAGANVVRMNFSHGTSEDHIQRAKKVRAIAARLGRQVAILGDLQGPKIRVST
FKDGKITLKVGDKFTLDSDLPKGEGNQESVGLDYKELPQDVSPNDILLLDDGRVQLQVTSVEGNKVHTRVTVGGPLSNNK
GINKKGGGLSADALTEKDKADIITAAEIKVDYLAISFPRNGEDMHYARRLARDAGLEAKLVAKVERAETVATSESIDDII
LASDVVMVARGDLGVEIGDPELIGVQKKLIRRARSLNRVVITATQMMESMINSPMPTRAEVMDVANAVLDGTDAVMLSGE
TAAGQYPVETVKSMADVCIGAEKMSEASLSTYRLDRTFETAEETIAMATMYSANHMEGIKAMIALTESGRTALMMSRLSS
GLPIFALSRNESTLNRAALYRGVTPVYFDAKCDAGLPTAQAAISSLKDQGYLHEGDLVIITQGDVMDVVGSTNCMRILPV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 1e-88 50
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-60 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-60 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-60 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-60 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
VP2039 NP_798418.1 pyruvate kinase II VFG0479 Protein 1e-60 41