Gene Information

Name : VP0356 (VP0356)
Accession : NP_796735.1
Strain :
Genome accession: NC_004603
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 353411 - 354823 bp
Length : 1413 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence : 
ATGAAAAAGACCAAAATCGTTTGTACGATTGGCCCTAAAACTGAATCTGTAGAGAAGCTAACTGAACTAGTAAACGCAGG
CATGAACGTAATGCGTCTTAACTTCTCTCACGGTGACTACGAAGAACACGGCACTCGTATCGCGAACTTCCGCAAAGTAA
TGGAAGCTACTGGCAAACAACTAGCAATCCTTCTAGATACTAAAGGTCCAGAAATCCGCACTATCAAACTAGAAGGCGGT
AACGACGTTGATCTAGTAGCTGGTCAAGAATTCACTTTCACAACTGACACTTCAGTTGTAGGTAACAAAGACAAAGTTGC
AGTAACTTACGCTGGCTTCGCAGCTGACCTAAACGTTGGTAACACTATCCTAGTAGACGACGGTCTAATCGAGATGGAAG
TTATCGCAACAACTGACACTGAAGTTAAATGTAAAGTTCTTAACAACGGTGCTCTAGGCGAAAACAAAGGTGTTAACCTT
CCTGGCGTTTCTGTAAACCTACCTGCTCTATCTGAAAAAGATAAGAACGACCTTAAATTCGGTTGTGAGCAAGGCGTTGA
TTTCGTAGCTGCATCTTTCATCCGTAAAGCTTCTGACGTTCAAGAAATCCGTGAAGTTCTAGCTGCAAACGGCGGCGAGA
ACATCCACATCATCTCTAAGATCGAAAACCAAGAAGGTGTTGATAACTTCGATGAGATCCTAGAACTTTCTGACGGCATC
ATGGTTGCTCGTGGCGACCTAGGTGTTGAAATCCCAGCTGAAGAAGTAATCTTCGCTCAGAAAATGATGATCGAGAAGTG
TAACCGTGCACGTAAGATGGTTATCACTGCAACTCAAATGCTTGATTCTATGATCAACAACCCACGTCCTACTCGTGCGG
AAGCAGGCGACGTTGCAAACGCAGTAATGGACGGCACAGACGCAGTAATGCTTTCTGGCGAAACAGCAAAAGGTAAATAC
CCTGTTGAAGCGGTAACTATCATGGCTCAAATCGCTAAGCGTACTGACTCTGTACTTAAAGCTGAACTAGGTTCTCGTCT
AGACAGCCCACGTCTACGCATCACTGAAGCAGTATGTAAAGGCGCAGTAGACACAGCTGAAAAACTGGCTGCTCCACTGA
TCGTTGTTGCAACTGAAGGCGGTAAGTCTGCACGTTCAGTACGTAAGTACTTCCCAACTGCAAACATCCTAGCGCTAACA
ACTAACAAGAAAACTGCAGCACAACTAGTTCTAACTAAGGGTGTTACTCCAGTTGTTGTTGACGCTATCGAAAGCACTGA
CGCATTCTACGTAGCAGGTAAAGAACTTGCTCTAGAATCTGGTCTAGGTAACAAAGGCGATATCGTAGTAATGGTTTCTG
GTGCTCTAGTCGCTTCAGGTACTACGAACACAGCTTCTGTACACGTACTATAA

Protein sequence : 
MKKTKIVCTIGPKTESVEKLTELVNAGMNVMRLNFSHGDYEEHGTRIANFRKVMEATGKQLAILLDTKGPEIRTIKLEGG
NDVDLVAGQEFTFTTDTSVVGNKDKVAVTYAGFAADLNVGNTILVDDGLIEMEVIATTDTEVKCKVLNNGALGENKGVNL
PGVSVNLPALSEKDKNDLKFGCEQGVDFVAASFIRKASDVQEIREVLAANGGENIHIISKIENQEGVDNFDEILELSDGI
MVARGDLGVEIPAEEVIFAQKMMIEKCNRARKMVITATQMLDSMINNPRPTRAEAGDVANAVMDGTDAVMLSGETAKGKY
PVEAVTIMAQIAKRTDSVLKAELGSRLDSPRLRITEAVCKGAVDTAEKLAAPLIVVATEGGKSARSVRKYFPTANILALT
TNKKTAAQLVLTKGVTPVVVDAIESTDAFYVAGKELALESGLGNKGDIVVMVSGALVASGTTNTASVHVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-176 79
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-176 79
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-176 79
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 7e-176 79

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
VP0356 NP_796735.1 pyruvate kinase VFG0479 Protein 6e-177 79