Gene Information

Name : lolD (S1201)
Accession : NP_836821.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Resistance
Product : lipoprotein transporter ATP-binding subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : -
Position : 1167253 - 1167954 bp
Length : 702 bp
Strand : +
Note : outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone

DNA sequence : 
ATGAATAAGATCCTGTTGCAATGCGACAACCTGTGCAAACGCTATCAGGAAGGCAGTGTGCAAACCGATGTGCTGCTCAA
TGTCAGTTTCAGCGTGGGCGAAGGTGAAATGATGGCAATTGTCGGTAGCTCTGGTTCCGGTAAAAGTACCTTGCTGCACC
TGTTAGGCGGGCTGGATACGCCAACCTCCGGCGATGTGATCTTTAACGGTCAGCCGATGAGCAAACTGTCTTCAGCGGCG
AAAGCAGAACTGCGCAACCAGAAGCTGGGCTTTATTTATCAGTTTCACCACCTGCTGCCGGATTTTACTGCCCTGGAAAA
CGTGGCTATGCCACTGCTGATTGGCAAGAAAAAGCCCGCTGAAATCAACAGCTGTGCACTGGAGATGTTAAAAGCGGTGG
GGCTGGAGCATCGTGCGAATCACCGCCCATCTGAACTTTCTGGCGGCGAACGCCAGCGTGTAGCGATTGCCCGTGCGCTG
GTCAATAATCCGCGTCTGGTACTGGCGGATGAACCTACCGGTAACCTCGATGCGCGTAACGCCGACAGCATCTTCCAGTT
GCTTGGGGAGTTGAATCGCTTGCAGGGCACCGCTTTCCTGGTGGTCACTCACGACCTGCAACTGGCGAAACGTATGAGCC
GCCAACTGGAAATGCGTGATGGACGTCTGACGGCGGAACTGAGCCTGATGGGGGCGGAGTAA

Protein sequence : 
MNKILLQCDNLCKRYQEGSVQTDVLLNVSFSVGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAA
KAELRNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSCALEMLKAVGLEHRANHRPSELSGGERQRVAIARAL
VNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEMRDGRLTAELSLMGAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 2e-26 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lolD NP_836821.1 lipoprotein transporter ATP-binding subunit NC_008702.1.4606598. Protein 4e-36 48
lolD NP_836821.1 lipoprotein transporter ATP-binding subunit NC_012469.1.7686878. Protein 1e-40 45