Gene Information

Name : cysB (S1362)
Accession : NP_836968.1
Strain : Shigella flexneri 2457T
Genome accession: NC_004741
Putative virulence/resistance : Unknown
Product : transcriptional regulator CysB
Function : -
COG functional category : K : Transcription
COG ID : COG0583
EC number : -
Position : 1328006 - 1328980 bp
Length : 975 bp
Strand : +
Note : LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes

DNA sequence : 
ATGAAATTACAACAACTTCGCTATATTGTTGAGGTGGTCAATCATAACCTGAATGTCTCATCAACAGCGGAAGGACTTTA
CACATCACAACCCGGGATCAGTAAACAAGTCAGAATGCTGGAAGACGAGCTAGGCATTCAAATTTTTTCCCGAAGCGGCA
AGCACCTGACGCAGGTAACGCCAGCAGGACAAGAAATAATTCGTATCGCTCGCGAAGTCCTGTCGAAAGTCGATGCCATA
AAATCGGTTGCCGGTGAGCACACCTGGCCGGATAAAGGCTCGCTGTATATCGCCACCACGCATACCCAGGCACGCTACGC
GTTACCAAACGTTATCAAAGGCTTTATTGAGCGTTATCCCCGCGTTTCTTTGCATATGCACCAGGGCCCGCCGACACAAA
TTGCTGATGCCGTCTCTAAAGGCAATGCCGATTTCGCTATCGCCACAGAAGCGCTGCATCTGTATGAAGATTTAGTGATG
TTACCGTGCTACCACTGGAATCGGGCTATTGTAGTCACTCCGGATCACCCGCTGGCAGGCAAAAAAGCCATTACCATTGA
AGAACTGGCGCAATATCCGTTGGTGACATATACCTTCGGCTTTACCGGACGTTCAGAACTGGATACTGCCTTTAACCGCG
CAGGGTTAACGCCGCGTATCGTTTTCACGGCAACGGATGCTGACGTCATTAAAACTTACGTCCGGTTAGGGCTGGGGGTA
GGGGTCATTGCCAGCATGGCGGTGGATCCGGTCGCCGATCCCGACCTTGTGCGCGTTGATGCTCACGATATCTTCAGCCA
CAGTACAACCAAAATTGGTTTTCGCCGTAGTACTTTTTTGCGCAGTTATATGTATGATTTCATTCAGCGTTTTGCACCGC
ATTTAACGCGTGATGTCGTTGATGCGGCTGTCGCATTGCGCTCCAATGAAGAAATTGAGGTCATGTTTAAAGATATAAAA
CTGCCGGAAAAATAA

Protein sequence : 
MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDELGIQIFSRSGKHLTQVTPAGQEIIRIAREVLSKVDAI
KSVAGEHTWPDKGSLYIATTHTQARYALPNVIKGFIERYPRVSLHMHQGPPTQIADAVSKGNADFAIATEALHLYEDLVM
LPCYHWNRAIVVTPDHPLAGKKAITIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTPRIVFTATDADVIKTYVRLGLGV
GVIASMAVDPVADPDLVRVDAHDIFSHSTTKIGFRRSTFLRSYMYDFIQRFAPHLTRDVVDAAVALRSNEEIEVMFKDIK
LPEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cbl YP_853089.1 transcriptional regulator Cbl Not tested PAI IV APEC-O1 Protein 6e-59 42