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Name : iscS (Erum4150) Accession : YP_180280.1 Strain : Ehrlichia ruminantium Welgevonden Genome accession: NC_005295 Putative virulence/resistance : Unknown Product : cysteine desulfurase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG1104 EC number : 4.4.1.- Position : 721640 - 722881 bp Length : 1242 bp Strand : + Note : catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis DNA sequence : ATGGAAAAAATAAAAGATATACAACGACATATTAATCTACCTATATTTCTTGATTATCAATCCACAACTAAAACGGATAG TAGAGTCTTAGATGCTATGATTCCATATTTTCAAGAGTTTTCTAATCCTCATTCACGTAGTCATTGTTTTGGATGGAAAG CTGAGTCGGCTGTTGAATTAGCACGAGAAAGAATTGCATCTTTAATAAATGCTGAAAGTAAAGAAGTAATATTCACTTCT GGTGCTACAGAATCAAATAATTTGGCAATCAAAGGTGTAGCAAACTTTTATAAAAGTAAAGGAAATCACATTATTACAGT ACGTACAGAGCATAAATGTGTTTTAGATTCATGTCGCCATTTAGAAACAGAAGGATTTGATGTTACTTACTTAGATGTAC AAAAAAATGGTATTTTAGATCTTAATTTATTAAAATCAGCTATAACTGATAAGACTATATTGGTATCGGTTATGATGGTG AACAATGAAATTGGTGTCATTCAACCAATAGAGGAAATAGGAAAAATTTGTCATAATCATGGAGTATTCTTTCATACTGA TGCAGCTCAAGCATTTGGTAAAATACCAATAGATGTAAACAAAATGAATATAGATTTGCTTAGTATATCAGGACATAAAA TATATGCTCCAATGGGAATAGGGGCATTATATGTACGTAAACGTCAACCAAGAATACGACTTACTCCTATAATAAATGGT GGTGGACAAGAACGTGGTATGAGATCTGGAACCATACCTACTCCATTAGCAGTAGGTTTAGGTGAAGCAGCATATATAGC TCAGGAAGTAATGGAAGATGAAGCCATTAGGATAAAAGAATTACGTGATATTTTATATAGTGAAATAAAAAAACATTTAC CCTATGTAATACTGAATGGTGATTATGAACAACGTATAGCAGGAAATTTAAATTTAAGTTTTCCATATGTAGAAGGAGAA TCTATTATTATGGCGATTAACAACTTAGCAGTAAGTTCAGGATCTGCTTGTACATCTGCTTCACTAGAACCATCTTATGT TTTACGTGCGTTAAATATAGATAAGGATTTAGAACACTCATCTATTAGATTTGGAATAGGTAGGTTTACTACAAAAGCAG AAATTTTATATGCAGCGGATCTTATTGTAAATAGCATAAAGAGGTTGCGTGAGATGAGTCCTTTATGGGAAATGGTACAA GAAGGTATAAATCTTAATGAAATTAAGTGGGATGTGCATTAA Protein sequence : MEKIKDIQRHINLPIFLDYQSTTKTDSRVLDAMIPYFQEFSNPHSRSHCFGWKAESAVELARERIASLINAESKEVIFTS GATESNNLAIKGVANFYKSKGNHIITVRTEHKCVLDSCRHLETEGFDVTYLDVQKNGILDLNLLKSAITDKTILVSVMMV NNEIGVIQPIEEIGKICHNHGVFFHTDAAQAFGKIPIDVNKMNIDLLSISGHKIYAPMGIGALYVRKRQPRIRLTPIING GGQERGMRSGTIPTPLAVGLGEAAYIAQEVMEDEAIRIKELRDILYSEIKKHLPYVILNGDYEQRIAGNLNLSFPYVEGE SIIMAINNLAVSSGSACTSASLEPSYVLRALNIDKDLEHSSIRFGIGRFTTKAEILYAADLIVNSIKRLREMSPLWEMVQ EGINLNEIKWDVH |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | AAT96060.1 | cysteine desulfurase | Not tested | T-PAI | Protein | 1e-109 | 55 |
