Gene Information

Name : copR (YP_1848)
Accession : NP_993191.1
Strain : Yersinia pestis 91001
Genome accession: NC_005810
Putative virulence/resistance : Virulence
Product : transcriptional activator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2058865 - 2059557 bp
Length : 693 bp
Strand : -
Note : highly similar to Yersinia pestis CO92 copR and Yersinia pestis KIM y2307. Contains Response regulator receiver (Interpro|IPR001789, (GO:0006355)). Contains Transcriptional regulatory protein, C terminal (Interpro|IPR001867, (GO:0006355)). Contains Heavy

DNA sequence : 
ATGCGGCTATTGTTGGTAGAAGATGAGGAGAAGACATCTTCGTATATCAATCGCGCCCTCAGCGAGTTGGGCTTTACCGT
CGATGTAGCGGCCACCGGGATCGACGGATTATATCTGGCTCTTGAGTATGATTACGATACGATTGTGCTCGATGTCATGT
TGCCCGGCATGGATGGTTACAGCGTTCTCGAAGGCCTACGCGCCAGCAAACAAACTCCGGTTCTGATGTTATCCGCCCGT
GGCTCGGTTGATGAACGAGTTAAGGGCCTGCGTCACGGTGCCGACGATTATTTGCCTAAGCCTTTTTCGCTGATTGAACT
GGTTGCGCGTATCCAGGCGTTGTTGAGGCGGCGTCCCAGTGATGGTGTAGATGTCAGCCAATTGCACATTAATGATCTAC
ATCTCGACCTGCTGGCAAGGCGTGTCACGCGAGCCGGTGAACGTCTTGAACTCACCGCCAAAGAGTTCGCCCTGTTAAGC
CTGTTAGCCAGACATCAGGGGGAAATTCTGTCAAAAATGATGATTGCAGAGCAGGTCTGGGACATGAATTTTGACAGCGA
TGCTAATGTCGTTGAGGTGGCGATAAAACGCCTGCGGGCGAAAATAGATACGCCCTACCCGGTCAAACTGCTGCATACAG
TGCGAGGCATGGGGTATGTCCTTGAAACTCGCCCCGATCGCCAGACTAAATAG

Protein sequence : 
MRLLLVEDEEKTSSYINRALSELGFTVDVAATGIDGLYLALEYDYDTIVLDVMLPGMDGYSVLEGLRASKQTPVLMLSAR
GSVDERVKGLRHGADDYLPKPFSLIELVARIQALLRRRPSDGVDVSQLHINDLHLDLLARRVTRAGERLELTAKEFALLS
LLARHQGEILSKMMIAEQVWDMNFDSDANVVEVAIKRLRAKIDTPYPVKLLHTVRGMGYVLETRPDRQTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 8e-54 50
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-52 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
copR NP_993191.1 transcriptional activator BAC0083 Protein 2e-62 61
copR NP_993191.1 transcriptional activator BAC0197 Protein 4e-60 58
copR NP_993191.1 transcriptional activator BAC0638 Protein 7e-53 57
copR NP_993191.1 transcriptional activator BAC0125 Protein 8e-61 56
copR NP_993191.1 transcriptional activator BAC0111 Protein 1e-59 53
copR NP_993191.1 transcriptional activator BAC0347 Protein 1e-52 51
copR NP_993191.1 transcriptional activator BAC0308 Protein 3e-52 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
copR NP_993191.1 transcriptional activator VFG0596 Protein 3e-54 50
copR NP_993191.1 transcriptional activator VFG1389 Protein 2e-38 48
copR NP_993191.1 transcriptional activator VFG1390 Protein 3e-40 44
copR NP_993191.1 transcriptional activator VFG1386 Protein 5e-35 43