Gene Information

Name : PBPRA0428 (PBPRA0428)
Accession : YP_128662.1
Strain :
Genome accession: NC_006370
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 441531 - 442943 bp
Length : 1413 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence : 
ATGAAAAAGACCAAGATCGTATGTACGATTGGACCAAAAACTGAATCTGTAGAAATGCTGACTAAACTAGCTAACGCTGG
TATGAACGTAATGCGTTTAAACTTCTCTCACGGTAACTTCGAAGAACACGGTCAACGTATCGTAAACCTACGTGAAGTAA
TGGCTACATCTGCTCAGCCTCTAGCTATCTTGCTAGATACTAAAGGTCCTGAAATTCGTACTATCAAACTAGAAAATGGC
GAAGATTTCGCTCTAGTTGCTGGTCAAGAATTCACATTCACAACTGATATTACAGTTGTTGGCAACCAAGACCGCGTTGC
AGTAACTTACCCAGGTTTCGCTAAAGACCTTACTAAAGGTAACATCATCCTTGTTGATGATGGTCTTATCGAAATGGAAG
TACTAGAAACAACTGAAACTGAAGTTAAGTGTAAAGTACTTAACAACGGTGACCTTGGTGAAAACAAAGGTGTTAACCTA
CCTGGTGTTTCTGTAAAGCTTCCTGCTCTTTCTGAAAAAGATAAAGCAGACCTAGTATTCGGTTGTGAGCAAGGCGTTGA
TTTCGTTGCTGCATCTTTCATTCGTAAAGAAGATGATGTTAAAGAAATCCGTGCTCTACTTGCTGCTAACGGTGGCGAGA
AGATTCAAATCATCTCTAAAATCGAAAACCAGGAAGGCGTTGATAACTTTGACTCTATCCTAGAAGCTTCTGACGGTATC
ATGGTTGCTCGTGGCGACCTTGGTGTTGAAATCCCAGTAGAAGAAGTTATCTTTGCTCAGAAGATGATGATCGAGAAATG
TAATCGCGCACGTAAAGTTGTTATCACTGCAACTCAAATGCTTGATTCTATGATTAAGAACCCACGTCCGACTCGCGCAG
AAGCGGGTGACGTTGCAAACGCAATCATGGATGGTACTGATGCAGTCATGCTATCTGGTGAATCAGCTAAGGGTAAATAC
CCAATTGAAGCTGTAACTATCATGGCTCAAATCTGTAACCGTACAGATTCAGCGTTAAAAGCAGAATTAGGTTCTCGCCT
AGACAGCTCTCGTCTACGTATTACTGAAGCTGTATGTAAAGGCGCAGTAGACACTTCAGAGAAGCTAAATGCTCCTCTAA
TTGTTGTTGCTACTGAAGCGGGTAAATCTGCTCGCTCTATCCGTAAGTACTTCCCAACAGCGAAAATTATTGCTGTAACT
ACAAACCAGAAAACAGCTGCTCAGCTTTGTCTAACGAAAGGTGTTACACCTATCGTTGTTGATGCTATCGACAACACTGA
TGCATTCTACAGTCGCGGTAAAGAAATCGCGCTAGAAACTGGTCTTGGCGCTAAAGGCGATATCGTTGTTATGGTATCTG
GCGCACTAGTTCCTTCTGGTACAACTAACACAGCTTCTGTACACGTACTTTAA

Protein sequence : 
MKKTKIVCTIGPKTESVEMLTKLANAGMNVMRLNFSHGNFEEHGQRIVNLREVMATSAQPLAILLDTKGPEIRTIKLENG
EDFALVAGQEFTFTTDITVVGNQDRVAVTYPGFAKDLTKGNIILVDDGLIEMEVLETTETEVKCKVLNNGDLGENKGVNL
PGVSVKLPALSEKDKADLVFGCEQGVDFVAASFIRKEDDVKEIRALLAANGGEKIQIISKIENQEGVDNFDSILEASDGI
MVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAIMDGTDAVMLSGESAKGKY
PIEAVTIMAQICNRTDSALKAELGSRLDSSRLRITEAVCKGAVDTSEKLNAPLIVVATEAGKSARSIRKYFPTAKIIAVT
TNQKTAAQLCLTKGVTPIVVDAIDNTDAFYSRGKEIALETGLGAKGDIVVMVSGALVPSGTTNTASVHVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-173 76
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-173 76
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-173 76
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-172 76

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PBPRA0428 YP_128662.1 pyruvate kinase VFG0479 Protein 6e-174 76