Gene Information

Name : pykF (VF_2258)
Accession : YP_205641.1
Strain :
Genome accession: NC_006840
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2533972 - 2535384 bp
Length : 1413 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence : 
ATGAAAAAGACCAAAATCGTTTGTACGATCGGCCCAAAAACTGAATCAGTTGAAAAACTAACTGAACTAGCAAATGCTGG
TATGAACGTTATGCGCCTAAACTTCTCACACGGCGACTTCGCAGAACACGGCCAACGTATTGATAACGTACGTCAAGTAA
TGAAAAACACTGGTAAACAACTTGCTATTCTTCTTGATACTAAAGGTCCTGAAATCCGTACAATCAAACTAGAAAACGGC
GACGATGTTGCTCTAGTTGCAGGTCAAGATTTCACATTCACAACAGATACTTCAGTTGTTGGTAATAAAGACGTTGTTGC
TGTTACTTACCCAGGTTTTGCAAACGACCTTGAAGTTGGTAACACTATCCTTGTTGATGACGGCCTAATCGAAATGGAAG
TTGTTGCGACAACTGAAACTGAAGTTAAGTGTAAAGTTCTTAACAACGGTGACCTAGGCGAAAACAAAGGTGTTAACCTT
CCTGGCGTTTCTGTTCAACTTCCAGCTCTATCTGAAAAAGATAAAGCTGACCTTAAATTTGGTTGTGAGCAAGGCGTTGA
TTTCGTTGCTGCTTCTTTCATTCGTAAAGAAGAAGACGTTAAAGAAATCCGTGAACTACTTGTTGCTAACGGCGGCGAGA
ACATTCAAATCATCTCTAAGATTGAAAACCAAGAAGGTGTTGATAACTTCGATTCAATCCTAGAAGCTTCTGACGGTATC
ATGGTTGCTCGTGGTGACCTTGGTGTTGAAATCCCAGTTGAAGAAGTAATCTTCGCTCAGAAGATGATGATCGAGAAATG
TAACCGTGCACGTAAAGTTGTAATCACTGCAACTCAAATGCTTGATTCTATGATCAAAAACCCACGTCCAACTCGTGCTG
AAGCGGGTGACGTTGCGAACGCAATCATGGATGGTACTGATGCTGTAATGCTTTCAGGTGAATCTGCTAAAGGTAAATAC
CCAGTTGAAGCTGTAACTATTATGGCTCAAATCTGTGCTCGTACTGACGCAGCTCTTAAAGCAGAACTAGGTTCTCGTCT
AGATAGCCCACGTCTACGTATCACTGAAGCGGTATGTAAAGGTGCAGTAGATACAGCTGAGAAACTAAACGCTCCTGTTA
TCGTTGTTGCAACTGAAGCTGGTAAATCAGCTCGTTCAATCCGTAAATACTTCCCAACAGCTAAAATCATCGCTGTAACT
ACTAATACTAAGACTGCTGCACAACTATGTCTTTCTAAAGGTATTACTCCAATGATCGTTGATTCAATCGATAGCACTGA
CGCATTCTACCTACGTGGTAAAGAGTTAGCTCTTGAATCAGGTATTGGCGCTAAAGGCGATATCGTTGTTATGGTTTCTG
GTGCTCTAGTTCCATCTGGTACTACAAACACAGCTTCTGTACACGTTCTATAA

Protein sequence : 
MKKTKIVCTIGPKTESVEKLTELANAGMNVMRLNFSHGDFAEHGQRIDNVRQVMKNTGKQLAILLDTKGPEIRTIKLENG
DDVALVAGQDFTFTTDTSVVGNKDVVAVTYPGFANDLEVGNTILVDDGLIEMEVVATTETEVKCKVLNNGDLGENKGVNL
PGVSVQLPALSEKDKADLKFGCEQGVDFVAASFIRKEEDVKEIRELLVANGGENIQIISKIENQEGVDNFDSILEASDGI
MVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAIMDGTDAVMLSGESAKGKY
PVEAVTIMAQICARTDAALKAELGSRLDSPRLRITEAVCKGAVDTAEKLNAPVIVVATEAGKSARSIRKYFPTAKIIAVT
TNTKTAAQLCLSKGITPMIVDSIDSTDAFYLRGKELALESGIGAKGDIVVMVSGALVPSGTTNTASVHVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-173 79
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-173 79
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-173 79
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-172 78

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_205641.1 pyruvate kinase VFG0479 Protein 7e-174 79