Gene Information

Name : cysB (APL_0133)
Accession : YP_001052846.1
Strain : Actinobacillus pleuropneumoniae L20
Genome accession: NC_009053
Putative virulence/resistance : Unknown
Product : transcriptional regulator CysB
Function : -
COG functional category : K : Transcription
COG ID : COG0583
EC number : -
Position : 148207 - 149190 bp
Length : 984 bp
Strand : +
Note : LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes

DNA sequence : 
ATGAAATTACAGCAATTACGCTACATCGTTGAAATTGTAAATCAAAATCTGAATATTACCGAAGCGGCGGAAACACTTTA
CACTTCTCAACCGGGCATTAGTAAGCAGGTACGTCTATTGGAAAGCGAACTCGGAATTAATATTTTCGAACGAAACGGTA
AGCATATTAAAGGATTAACGCCGGCGGGAGAAAAAATTGTCGCGATTGCGCGCGAATTACTGGTAAAAGCGCAGAGTATT
AAATCGGTGGCGGAAGAACAGACTCGTCCGAATCGAGGCGTCTTACGCATTGCAACGCCGAATACGCAAGCGCGCTATGT
TTTGCCGCCGATTATTGAGAAATTCAAAGCGAAGTATCCGGAGGTCAGCCTACAATTACATCAAGGTTCGCCAAGTCAAA
TTTACGATGCCTTAATGGCGGGCGAAGTGGATCTGGCGATTACGACCGAAGCGCAGCATTTATTTGAAGATGCGATCTTA
TTGCCGTGTTATTTATGGAATCGTTCCGTCATTGTGAAGCCGGATCATCCGTTAGTAAAATTTGTGAACCAAAGCGAGAA
TTTAACGGTCGAAGAACTCGGTAAATATGATTTGATTACTTATACTTTCGGCTTTACCGGACAATCCGATCTCGACCATG
CGTTTAATAAAGAAGGTATCTTACCGCATATCGTGTTTACTGCGACGGATGCCGACGTCATTAAAACTTACGTGCGTTTA
GGCTTAGGGGTCGGGATTATGGCGTCAATGGCGCATACGCCCGCGGACAGTGATTTGGTGGCGATTGATGCAAGTCATTT
ATTCCAATCGAGTATGACGCAAATCGCATTTAAACGCGGCACTTTCTTACGTAATTATATGTATGATTTTATTAACTATT
TCTCGCCGCATTTAACAAAGATGCAAGTAGAGAAAGCGGAACAATTAAGAGAGAGCAATGCTATTCTTCGTTTGTTCGAA
AGCACTAAATTAGAGGAAAAATAG

Protein sequence : 
MKLQQLRYIVEIVNQNLNITEAAETLYTSQPGISKQVRLLESELGINIFERNGKHIKGLTPAGEKIVAIARELLVKAQSI
KSVAEEQTRPNRGVLRIATPNTQARYVLPPIIEKFKAKYPEVSLQLHQGSPSQIYDALMAGEVDLAITTEAQHLFEDAIL
LPCYLWNRSVIVKPDHPLVKFVNQSENLTVEELGKYDLITYTFGFTGQSDLDHAFNKEGILPHIVFTATDADVIKTYVRL
GLGVGIMASMAHTPADSDLVAIDASHLFQSSMTQIAFKRGTFLRNYMYDFINYFSPHLTKMQVEKAEQLRESNAILRLFE
STKLEEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cbl YP_853089.1 transcriptional regulator Cbl Not tested PAI IV APEC-O1 Protein 6e-54 41