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Name : apxIA (APL_1444) Accession : YP_001054133.1 Strain : Actinobacillus pleuropneumoniae L20 Genome accession: NC_009053 Putative virulence/resistance : Virulence Product : RTX-I toxin determinant A Function : - COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism COG ID : COG2931 EC number : - Position : 1652927 - 1655995 bp Length : 3069 bp Strand : - Note : pubmed:8359891 DNA sequence : ATGGCTAACTCTCAGCTCGATAGAGTCAAAGGATTGATTGATTCACTTAATCAACATACAAAAAGTGCAGCTAAATCAGG TGCCGGCGCATTAAAAAATGGTTTGGGACAGGTGAAGCAAGCAGGGCAGAAATTAATTTTATATATTCCGAAAGATTATC AAGCTAGTACCGGCTCAAGTCTTAATGATTTAGTGAAAGCGGCGGAGGCTTTAGGGATCGAAGTACATCGCTCGGAAAAA AACGGTACCGCACTAGCGAAAGAATTATTCGGTACAACGGAAAAACTATTAGGTTTCTCGGAACGAGGCATCGCATTATT TGCACCTCAGTTTGATAAGTTACTGAATAAGAACCAAAAATTAAGTAAATCGCTCGGCGGTTCATCGGAAGCATTAGGAC AACGTTTAAATAAAACGCAAACGGCACTTTCAGCCTTACAAAGTTTCTTAGGTACGGCTATTGCGGGTATGGATCTTGAT AGCCTGCTTCGTCGCCGTAGAAACGGTGAGGACGTCAGTGGTTCGGAATTAGCTAAAGCGGGTGTGGATCTAGCCGCTCA GTTAGTGGATAACATTGCAAGTGCAACGGGTACGGTGGATGCGTTTGCCGAACAATTAGGTAAATTGGGCAATGCCTTAT CTAACACTCGCTTAAGCGGTTTAGCAAGTAAGTTAAATAACCTTCCAGATTTAAGCCTTGCAGGACCTGGGTTTGATGCC GTATCAGGTATCTTATCTGTTGTTTCGGCTTCATTCATTTTAAGTAATAAAGATGCCGATGCAGGTACAAAAGCGGCGGC AGGTATTGAAATCTCAACTAAAATCTTAGGCAATATCGGTAAAGCGGTTTCTCAATATATTATTGCGCAACGTGTGGCGG CAGGCTTATCCACAACTGCGGCAACCGGTGGTTTAATCGGTTCGGTCGTAGCATTAGCGATTAGCCCGCTTTCGTTCTTA AATGTTGCGGATAAGTTTGAACGTGCGAAACAGCTTGAACAATATTCGGAGCGCTTTAAAAAGTTCGGTTATGAAGGTGA TAGTTTATTAGCTTCATTCTACCGTGAAACCGGTGCGATTGAAGCGGCATTAACCACGATTAACAGTGTGTTAAGTGCGG CTTCCGCAGGTGTTGGGGCTGCTGCAACCGGCTCATTAGTCGGTGCGCCGGTAGCAGCTTTAGTTAGTGCAATCACCGGT ATTATTTCAGGTATTTTAGATGCTTCTAAACAGGCAATCTTCGAACGAGTTGCAACGAAATTAGCGAATAAGATTGACGA ATGGGAGAAAAAACACGGTAAAAACTATTTTGAAAACGGTTATGACGCCCGCCATTCCGCATTCTTAGAAGATACCTTTG AATTGTTATCACAATACAATAAAGAGTATTCGGTAGAGCGTGTCGTTGCTATTACGCAACAACGTTGGGATGTCAATATC GGGGAACTTGCCGGTATCACGCGTAAAGGTGCGGATGCGAAAAGCGGTAAGGCTTATGTCGATTTCTTTGAAGAAGGAAA ATTGTTAGAGAAAGATCCGGATCGTTTTGATAAAAAAGTGTTTGATCCGCTTGAAGGCAAAATCGACCTTTCTTCAATTA ACAAAACCACTTTATTGAAATTTATTACACCGGTTTTTACCGCAGGTGAAGAGATTCGTGAGCGTAAGCAAACCGGTAAA TACGAATATATGACCGAATTATTCGTTAAAGGTAAAGAAAAATGGGTGGTAACCGGTGTGCAGTCACATAATGCGATTTA TGACTATACGAATCTTATCCAATTAGCGATAGATAAAAAAGGTGAAAAACGTCAAGTGACCATTGAATCTCATTTGGGTG AGAAAAATGATCGTATATATCTTTCATCCGGTTCATCTATCGTATATGCGGGTAACGGACATGATGTAGCATATTACGAT AAAACCGATACAGGTTACTTAACATTTGACGGACAAAGTGCACAGAAAGCCGGTGAATATATTGTCACTAAAGAACTTAA AGCTGATGTAAAAGTTTTAAAAGAAGTGGTTAAAACTCAGGATATTTCAGTTGGAAAACGCAGTGAAAAATTAGAATATC GTGATTATGAGTTAAGCCCATTCGAACTTGGGAACGGTATCAGAGCTAAAGATGAATTACATTCTGTTGAAGAAATTATC GGTAGTAATCGTAAAGACAAATTCTTTGGTAGTCGCTTTACCGATATTTTCCATGGTGCGAAAGGCGATGATGAAATCTA CGGTAATGACGGCCACGATATCTTATACGGAGACGACGGTAATGATGTAATCCATGGCGGTGACGGTAACGACCATCTTG TTGGTGGTAACGGAAACGACCGATTAATCGGCGGAAAAGGTAATAATTTCCTTAATGGCGGTGATGGTGACGATGAGTTG CAGGTCTTTGAGGGTCAATACAACGTATTATTAGGTGGTGCGGGTAATGACATTCTGTATGGCAGCGATGGTACTAACTT ATTTGACGGTGGTGTAGGCAATGACAAAATCTACGGTGGTTTAGGTAAGGATATTTATCGCTACAGTAAGGAGTACGGTC GTCATATCATTATTGAGAAAGGCGGTGATGATGATACGTTATTGTTATCGGATCTTAGTTTTAAAGATGTAGGATTTATC AGAATCGGTGATGATCTTCTTGTGAATAAAAGAATCGGAGGAACACTGTATTACCATGAAGATTACAATGGGAATGCGCT CACGATTAAAGATTGGTTCAAGGAAGGTAAAGAAGGACAAAATAATAAAATTGAAAAAATCGTTGATAAAGATGGAGCTT ATGTTTTAAGCCAATATCTGACTGAACTGACAGCTCCTGGAAGAGGTATCAATTACTTTAATGGGTTAGAAGAAAAATTG TATTATGGAGAAGGATATAATGCACTTCCTCAACTCAGAAAAGATATTGAACAAATCATTTCATCTACTGGTGCACTTAC CGGTGAACACGGACAAGTTTTAGTGGGAGCAGGCGGTCCATTAGCTTACAGCAATTCACCGAATAGCATACCGAATGCTT TCAGTAATTATTTAACACAATCTGCTTAA Protein sequence : MANSQLDRVKGLIDSLNQHTKSAAKSGAGALKNGLGQVKQAGQKLILYIPKDYQASTGSSLNDLVKAAEALGIEVHRSEK NGTALAKELFGTTEKLLGFSERGIALFAPQFDKLLNKNQKLSKSLGGSSEALGQRLNKTQTALSALQSFLGTAIAGMDLD SLLRRRRNGEDVSGSELAKAGVDLAAQLVDNIASATGTVDAFAEQLGKLGNALSNTRLSGLASKLNNLPDLSLAGPGFDA VSGILSVVSASFILSNKDADAGTKAAAGIEISTKILGNIGKAVSQYIIAQRVAAGLSTTAATGGLIGSVVALAISPLSFL NVADKFERAKQLEQYSERFKKFGYEGDSLLASFYRETGAIEAALTTINSVLSAASAGVGAAATGSLVGAPVAALVSAITG IISGILDASKQAIFERVATKLANKIDEWEKKHGKNYFENGYDARHSAFLEDTFELLSQYNKEYSVERVVAITQQRWDVNI GELAGITRKGADAKSGKAYVDFFEEGKLLEKDPDRFDKKVFDPLEGKIDLSSINKTTLLKFITPVFTAGEEIRERKQTGK YEYMTELFVKGKEKWVVTGVQSHNAIYDYTNLIQLAIDKKGEKRQVTIESHLGEKNDRIYLSSGSSIVYAGNGHDVAYYD KTDTGYLTFDGQSAQKAGEYIVTKELKADVKVLKEVVKTQDISVGKRSEKLEYRDYELSPFELGNGIRAKDELHSVEEII GSNRKDKFFGSRFTDIFHGAKGDDEIYGNDGHDILYGDDGNDVIHGGDGNDHLVGGNGNDRLIGGKGNNFLNGGDGDDEL QVFEGQYNVLLGGAGNDILYGSDGTNLFDGGVGNDKIYGGLGKDIYRYSKEYGRHIIIEKGGDDDTLLLSDLSFKDVGFI RIGDDLLVNKRIGGTLYYHEDYNGNALTIKDWFKEGKEGQNNKIEKIVDKDGAYVLSQYLTELTAPGRGINYFNGLEEKL YYGEGYNALPQLRKDIEQIISSTGALTGEHGQVLVGAGGPLAYSNSPNSIPNAFSNYLTQSA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hlyA | CAD33759.1 | hemolysin A | Virulence | PAI I 536 | Protein | 0.0 | 58 |
| hlyA | CAD42039.1 | HlyA protein | Virulence | PAI II 536 | Protein | 0.0 | 58 |
| hlyA | NP_755445.1 | hemolysin A | Virulence | PAI I CFT073 | Protein | 0.0 | 58 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| apxIA | YP_001054133.1 | RTX-I toxin determinant A | VFG0840 | Protein | 0.0 | 59 |
| apxIA | YP_001054133.1 | RTX-I toxin determinant A | VFG1500 | Protein | 0.0 | 58 |
| apxIA | YP_001054133.1 | RTX-I toxin determinant A | VFG1558 | Protein | 0.0 | 58 |
| apxIA | YP_001054133.1 | RTX-I toxin determinant A | VFG0906 | Protein | 0.0 | 58 |
