Gene Information

Name : rpoB (BMA10247_3469)
Accession : YP_001082981.1
Strain :
Genome accession: NC_009080
Putative virulence/resistance : Unknown
Product : DNA-directed RNA polymerase subunit beta
Function : -
COG functional category : K : Transcription
COG ID : COG0085
EC number : 2.7.7.6
Position : 3413012 - 3417118 bp
Length : 4107 bp
Strand : +
Note : DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme

DNA sequence : 
ATGCAATATTCCTTCACCGAGAAGAAGCGCATTCGCAAGAGTTTCGCGAAGCGTTCCATCGTTCACCAAGTGCCTTTCCT
GCTGGCCACCCAGCTTGAATCATTCAGCACATTTCTGCAAGCCGATGTGCCCACCGCGCAACGCAAGTCCGAGGGGTTGC
AGGCCGCCTTCACGTCGGTGTTTCCCATCGTCTCGCATAACGGCTTCGCTCGTCTCGAGTTCGTGAGCTATGCGTTGTCG
TCGCCGGCGTTCAACATCAAGGAATGTCAGCAGCGCGGCCTGACCTACTGCTCGGCGCTGCGCGCGAAGGTGCGCCTCGT
GCTCCTCGACAAGGAGTCGCCGAGCAAGCCCGTCGTCAAGGAAGTGAAGGAACAGGAAGTGTACATGGGCGAGATTCCGC
TCATGACGCCGACCGGTTCGTTCGTCATCAACGGCACCGAGCGCGTGATCGTGTCGCAGTTGCACCGTTCGCCCGGCGTG
TTCTTCGAGCACGACAAGGGCAAGACGCACAGCTCGGGCAAGCTGCTGTTCTCCGCGCGGATCATTCCGTACCGCGGCTC
GTGGCTCGACTTCGAATTCGATCCGAAGGACGTGCTGTATTTCCGCGTCGACCGCCGCCGCAAGATGCCGGTCACGATCC
TGCTGAAGGCGATCGGCCTCACGCCTGAGCAGATCCTCGCGAACTTCTTCGTCTTCGACAACTTCACGCTGATGGACGAA
GGCGCGCAGATGGAGTTCGTGCCCGAGCGTCTGCGCGGCGAAGTCGCGCGCTTCGACATCACCGATCGCGAAGGCAAGGT
CATCGTCCAGAAGGACAAGCGGATCAACGCGAAGCACATTCGCGATCTCGAAGCCGCGAAGACCAAGTACATCTCGGTGC
CCGAAGACTATCTGCTCGGCCGCGTGCTGGCGAAGAACGTCGTCGACGGCGACACGGGTGAAGTGATCGCGAACGCGAAC
GACGAGATCACCGAAGGCGTGCTCGAGAAGCTGCGCGAAGCGAAGATCAAGGAAATCCAGACGCTCTACACGAACGATCT
GGACCAGGGCCCGTACATCTCGTCGACGCTGCGCGTGGACGAAACCGTCGACAAGACGGCCGCGCGCATCGCGATCTACC
GGATGATGCGCCCGGGCGAGCCGCCGACGGAAGAAGCCGTCGAGGCGCTCTTCAACCGCCTGTTCTACAGCGAAGACGCG
TACGACCTGTCGAAGGTCGGCCGCATGAAGTTCAACCGCCGCGTCGGCCGTGACGAGATCACGGGCCCGATGACGCTGCA
GGACGACGACATCCTCGCGACGATCAAGATCCTCGTCGAGCTGCGCAACGGCAAGGGCGAAGTCGACGACATCGACCACC
TCGGCAACCGTCGCGTGCGCTGCGTCGGCGAACTGGCGGAAAACCAGTTCCGCGCGGGCCTGGTGCGCGTCGAGCGCGCG
GTGAAGGAACGTCTCGGCCAGGCCGAGAGCGAAAACCTGATGCCGCACGACCTGATCAACTCGAAGCCGATTTCGTCGGC
GATTCGCGAGTTCTTCGGTTCGTCGCAGCTGTCGCAGTTCATGGACCAGACCAACCCGCTGTCGGAAATCACGCACAAGC
GCCGCGTGTCCGCACTGGGCCCGGGCGGTCTCACGCGCGAGCGCGCCGGCTTCGAAGTCCGCGACGTGCACCCGACCCAC
TACGGCCGCGTGTGTCCGATCGAGACGCCGGAAGGTCCGAACATCGGCCTCATCAACTCGCTCGCACTGTACGCGCACCT
GAACGAATACGGCTTCCTCGAGACGCCGTACCGCAAGGTCGTCGACAGCAAGGTGACCGACCAGATCGACTATCTGTCGG
CGATCGAGGAAGGCCGCTACATGATCGCGCAGGCGAACGCCGCGATCGGCGACGACGGCGCGCTCGTCGACGAACTGGTG
TCGTCGCGCGAAGCCGGCGAAACGATGATGGTCACGCCGGACCGCATCCAGTACATGGACGTCGCGCCGTCGCAGATCGT
GTCGGTGGCAGCCTCGCTGATTCCGTTCCTCGAGCACGATGACGCGAACCGCGCGCTGATGGGCTCGAACATGCAGCGTC
AGGCCGTGCCGTGTCTGCGTCCGGAGAAGCCCGTCGTCGGTACCGGCATCGAGCGCACCGTGGCGGTCGACTCGGGCACG
ACGGTGCAGGCGCTGCGCGGCGGCGTCGTCGATTACGTCGACGCGGGCCGTATCGTCATTCGCGTGAACGATGACGAAGC
GGTCGCGGGCGAAGTCGGCGTCGACATCTACAACCTGATCAAGTACACGCGTTCGAACCAGAACACGAACATCAATCAGC
GTCCGATCGTGAAGATGGGCGACAAGGTCTCGCGCGGCGACGTGCTGGCCGATGGCGCATCGACCGACCTGGGCGAGCTC
GCGCTCGGCCAGAACATGCTGATCGCGTTCATGCCGTGGAACGGCTACAACTTCGAGGATTCGATCCTGATCTCGGAGCG
CGTCGTCGCGGACGATCGCTACACGTCGATCCACATCGAAGAGCTGAACGTCGTCGCACGCGACACGAAGCTCGGGCCGG
AAGAAATCACGCGCGACATCTCGAACCTCGCGGAAGTCCAGCTCGGCCGTCTCGACGAATCGGGCATCGTGTACATCGGT
GCGGAAGTCGAAGCGGGCGACGTGCTGGTCGGCAAGGTCACGCCGAAGGGCGAGACCCAGCTGACGCCGGAAGAGAAGCT
GCTGCGCGCGATCTTCGGCGAGAAGGCGTCGGACGTGAAGGACACGTCGCTGCGCGTGCCGTCGGGCATGAGCGGCACCG
TGATCGACGTTCAGGTGTTCACGCGCGAAGGTATCCAGCGTGACAAGCGCGCGCAACAGATCATCGACGACGAACTGAAG
CGCTACCGTCTGGACTTGAACGACCAGCTGCGCATCGTCGAAGGCGACGCATTCCAGCGTCTCGCGCGCATGCTCGTCGG
CAAGGTCGCGAACGGCGGTCCGAAGAAGCTCGCGAAGGGCACGAAGATCGACCAGGCGTACCTGGAGGATCTCGACCACT
ACCACTGGTTCGACATCCGCCTCGCGGACGACGAAGCGGCCGTGCAGCTCGAAGCGATCAAGAACTCGATCGAAGAGAAG
CGCCACCAGTTCGACCTCGCGTTCGAAGAGAAGCGCAAGAAGCTCACGCAAGGCGACGAACTGCCGCCGGGCGTGCTGAA
GATGGTCAAGGTGTACCTCGCGGTGAAGCGCCGCCTACAGCCTGGCGACAAGATGGCGGGCCGTCACGGTAACAAGGGTG
TCGTGTCGAAGATCGTTCCGGTCGAAGACATGCCGTACATGGCCGACGGCCGTCCGGCCGACGTCGTGCTGAATCCGCTC
GGCGTGCCGTCGCGGATGAACGTGGGGCAGGTCCTGGAAGTGCACCTCGGCTGGGCCGCGAAGGGCCTCGGCTGGCGTAT
CGGCGAGATGCTCGCGCGTCAGACGAAGATCGAAGAGCTGCGTGTGTTCCTGACGAAGATCTACAACGAGTCGGGCCGTG
CGGAAGACCTCGAGAGCTTCAGCGACGACGAAATCCTCGAACTCGCGAAGAATCTGCGCGAAGGCGTGCCGTTCGCGACG
CCGGTGTTCGACGGCGCGACCGAGGAAGAAATGTCGAAGATGCTCGACCTCGCGTTCCCGGACGACATCGCCGAACAGCT
CGACATGAATCCGTCGAAGAACCAGGTGCGCCTGTACGACGGCCGCACGGGCGAGCCGTTCGAGCGCCGCGTGACGGTGG
GCTACATGCACTACCTGAAGCTGCACCACTTGGTCGACGACAAGATGCACGCGCGTTCGACGGGCCCGTACTCGCTCGTC
ACGCAGCAGCCGCTCGGCGGCAAGGCGCAGTTCGGCGGCCAGCGCTTCGGTGAAATGGAAGTGTGGGCGCTCGAAGCGTA
TGGCGCTTCGTACGTGCTGCAGGAAATGCTGACGGTGAAGTCGGACGACGTGACCGGCCGGACCAAGGTTTATGAAAACC
TGGTCAAGGGCGACCATGTCATCGACGCCGGCATGCCCGAGTCGTTCAACGTGTTGGTGAAGGAAATCCGGTCGCTCGGT
ATCGACATCGACCTGGACCGGAACTAA

Protein sequence : 
MQYSFTEKKRIRKSFAKRSIVHQVPFLLATQLESFSTFLQADVPTAQRKSEGLQAAFTSVFPIVSHNGFARLEFVSYALS
SPAFNIKECQQRGLTYCSALRAKVRLVLLDKESPSKPVVKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGV
FFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDVLYFRVDRRRKMPVTILLKAIGLTPEQILANFFVFDNFTLMDE
GAQMEFVPERLRGEVARFDITDREGKVIVQKDKRINAKHIRDLEAAKTKYISVPEDYLLGRVLAKNVVDGDTGEVIANAN
DEITEGVLEKLREAKIKEIQTLYTNDLDQGPYISSTLRVDETVDKTAARIAIYRMMRPGEPPTEEAVEALFNRLFYSEDA
YDLSKVGRMKFNRRVGRDEITGPMTLQDDDILATIKILVELRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERA
VKERLGQAESENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTH
YGRVCPIETPEGPNIGLINSLALYAHLNEYGFLETPYRKVVDSKVTDQIDYLSAIEEGRYMIAQANAAIGDDGALVDELV
SSREAGETMMVTPDRIQYMDVAPSQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPVVGTGIERTVAVDSGT
TVQALRGGVVDYVDAGRIVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPIVKMGDKVSRGDVLADGASTDLGEL
ALGQNMLIAFMPWNGYNFEDSILISERVVADDRYTSIHIEELNVVARDTKLGPEEITRDISNLAEVQLGRLDESGIVYIG
AEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGIQRDKRAQQIIDDELK
RYRLDLNDQLRIVEGDAFQRLARMLVGKVANGGPKKLAKGTKIDQAYLEDLDHYHWFDIRLADDEAAVQLEAIKNSIEEK
RHQFDLAFEEKRKKLTQGDELPPGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPVEDMPYMADGRPADVVLNPL
GVPSRMNVGQVLEVHLGWAAKGLGWRIGEMLARQTKIEELRVFLTKIYNESGRAEDLESFSDDEILELAKNLREGVPFAT
PVFDGATEEEMSKMLDLAFPDDIAEQLDMNPSKNQVRLYDGRTGEPFERRVTVGYMHYLKLHHLVDDKMHARSTGPYSLV
TQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVTGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLG
IDIDLDRN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00346 YP_008207811.1 DNA-directed RNA polymerase, beta subunit/140 kD subunit Not tested AbaR25 Protein 0.0 66
BJAB0868_00350 YP_008211676.1 DNA-directed RNA polymerase, beta subunit/140 kD subunit Not tested AbaR26 Protein 0.0 66

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta CP002695.1.gene18.p0 Protein 0.0 82
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_008702.1.4609796. Protein 0.0 77
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_011035.1.6448762. Protein 0.0 74
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_002516.2.881699.p Protein 0.0 68
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta CP000675.2.gene392.p Protein 0.0 67
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta CP000034.1.gene3741. Protein 0.0 66
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta CP001918.1.gene250.p Protein 0.0 66
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta CP001138.1.gene4362. Protein 0.0 66
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_002695.1.914942.p Protein 0.0 66
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_009085.4918494.p0 Protein 0.0 66
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta CP000647.1.gene4402. Protein 0.0 66
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_010410.6003841.p0 Protein 0.0 66
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_011586.7046027.p0 Protein 0.0 66
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_010400.5987325.p0 Protein 0.0 66
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_010611.6233925.p0 Protein 0.0 66
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_011595.7060572.p0 Protein 0.0 66
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta CP004022.1.gene2794. Protein 0.0 65
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta CP001581.1.gene3846. Protein 0.0 46
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta AM180355.1.gene120.p Protein 0.0 46
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_009632.5315067.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_009782.5559150.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_002758.1120515.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_002953.2862188.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_002952.2860169.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_007793.3914836.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_003923.1002608.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_013450.8613267.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_009641.5330265.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_002951.3236234.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_010079.5776819.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_009487.5169226.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_007622.3792928.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_002745.1123305.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_007795.3920377.p0 Protein 0.0 45
rpoB YP_001082981.1 DNA-directed RNA polymerase subunit beta NC_012469.1.7686402. Protein 2e-177 43