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Name : rpoB (FTW_0234) Accession : YP_001121321.1 Strain : Francisella tularensis WY96-3418 Genome accession: NC_009257 Putative virulence/resistance : Unknown Product : DNA-directed RNA polymerase subunit beta Function : - COG functional category : K : Transcription COG ID : COG0085 EC number : 2.7.7.6 Position : 239374 - 243450 bp Length : 4077 bp Strand : + Note : DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme DNA sequence : ATGTCTTACTCATACGCTGAGAAAAAAAGAATTCGTAAAGAGTTTGGGGTTCTTCCTCATATCTTAGATGTACCATATTT GCTTTCTATTCAAACAGAGTCATACAAAAAATTCTTGACTGCAGATGCAGCAAAAGGAAGACTTCACTCTGGACTTGAAA TAGTTTTAAAACAGTCTTTTCCTGTTGAGAGTAAAAATGGTCAATATGAACTTCACTATGTTGATTATCAAATTGGTGAG CCTACTTTTGATGAAACTGAATGTCAGGTTCGTGGTGCTACTTATGATGCACCATTAAATGTGAAGTTAAGATTAGTTGT ATATAATAAAGATGCTCTTCCAAATGAGAAAATTGTCGAGGACATTAGAGAAGAGTATGTGTACATGGGCGATATTCCGC TAATGACAACTAATGGTACTTTTATCATTAATGGGACAGAAAGAGTAGTAGTCTCTCAGTTGCATAGATCACCAGGGGTG TTCTTTAGTAAGGATGACTCTGAGGAAGGAGCATTCTCAGCACGTATTATCCCATATAGAGGCTCATGGCTTGATTTTGA ATTTGACTCAAAAGGTATTATATGGGCTAGGATTGATAGAAAAAGAAAATTCTGTGCTACAGTTATTTTAAAAGCTCTTG GTTATACTCAAGAGCAAATATTAGAGAATTTTTCTGAGAGTAAGACTATTACTTTTAATAGTAAAGGTTTTGCTCTTAGA CTTGATAACCTTTCAAATATGAAAGGTGAGCTGCTTAAGTTTGACATTGTAGATGCTCAAGATAATGTTATTGTTAAAAA GAATAAAAAATTAACTTCAAGAGATGTTAAGAAAATTAAAGATGCAGGCGTTGACTCTGTAGCTATTGATTTTGATTTGG TCAGCACTCTTAGAGTTGCAAAAGATATCGTTAATGAAGCAACAGGTGAAGTGATAGCTTATGCTAATGACGATGTTACA GAAAGTTTATTAGAGTCATGCGTAGAAGTTGGCATGCTTGAATTAGAAGTTATTGATTTTATAACTACTGAAAGAGGTAG GTATATATCTGATACTTTAAAATATGATCTTACAAGAAATACTGATGAGGCACTTGTCGAGATATATAAGGTATTACGAC CAGGTGATCCTCCTGCAGCAGCTTCAGTTAAAGCATTATTTGAAGGTTTATTCTTTATTGAAAGTAGATATAGCCTTTCT GATATTGGTAGAATGAAGCTAAATGCTAGATTGGGTTCGGATAAGGTATCTAAAGATATCTATACTTTAGAAAATAGTGA TATAGTTGGCGTAATTGAAGAGCTTATAAATATCCGTGATGGTAAAGGTAAAGTTGATGATATTGATCATTTAGGTAACA GACGTGTACGTTCTGTTGGCGAGATGGTTGAGAATCAGTTTAGAATAGGCCTCTACCGTGTAGAGAAAGGTATTCGTGAA AGTATGTCTTTAGTACATAAAGATAAGCTTATGCCAAAAGATATCGTTAACTCGAAGCCAATCACAGCAGCAATTAAAGA ATTCTTTACTTCTGGAGCGTTATCACAATTTATGGATCAAGATAACCCATTGTCAGAAGTTACACATAAGCGTAGAATAT CTGCATTAGGTCCAGGTGGTTTATCACGTGATAGAGCAGGTTTTGAAGTACGTGATGTTCATGCAACACACTATGGTAGA TTATGTCCAATTGAGACTCCAGAAGGTCCAAATATTGGTCTAATTAACTCATTAGCAAGTTATGCTCGTGTTAATGATTA TGGTTTCTTAGAAGCACCATATCGAAAAGTTGTTGATGGTAAGGTTACAGATGAAATTGAATACTTATCTGCTATCGATG AAGATAATTATGTAATTGCTCAAGCATCAACTAAACTTGATGAAAATAACCATTTTGTTGAAGATCTTATTCAATGTCGT TCTGGTGGTGAGGCAATATTTACTGAGTCAAGTAGAGTTCAGTATATGGATGTTTCTGCTAAACAGATGGTTTCAGCAGC TGCGGCACTAATTCCTTTCCTTGAGCATGATGATGCTAACAGGGTATTGATGGGTGCAAACATGCAACGTCAAGCGGTAC CGACTCTTAAATCTGAGAAGCCTTTAGTCGGTACAGGTATGGAGAAGATTGTTGCTAGAGATTCTGGTAATTGTATTATC GCAAGAAATGCTGGTGAAGTGGCTGAAGTTGATTCTAACAGAATCGTTATTAAAGTAGATACTGAAAAATCACAAACTAG TAATTTGGTTGATATTTATAGTTTAACTAAATTTAAACGCTCAAACAAAAATACTTGTATTAACCAGCGTCCAATAGTAA ATGTGGGTGATAAAGTAGAAGCTGGTGATATTTTAGCGGATGGTTTTGCAACTGATTTTGGTGAATTGTCACTAGGGCAT AACTTGATGGTTGCTTTTATGCCATGGAATGGTTATAACTTTGAGGATTCGATCTTACTATCTGAAAGAATAGTAAAAGA TGATAAGTATACTAGTATCCATATTGAAGAGTTCACATGTGTGGCTCGTGATACTAAGCTTGGTCCTGAAGAGATAACTG CAGATATTCCAAATGTTAGTGAGTCTAGTTTGGCAAAACTTGATGAATCAGGTATCGTCCATATTGGCGCTAATGTCGAA GCAGGCGATATTTTGGTAGCTAAGATTACTCCAAAAGCTGAGCAACAACTAACTCCTGAAGAGAGACTACTTAGAGCAAT CTTTAATGAAAAAGCATCAAATGTTGCTGATAGTTCATTAAGAATGCCAAGTGGTACTTCTGGTACGGTTATTAATGTTC AAGTATTTGAGAATGACAAAGGTGGTAAAAGTAAGCGAGCTCTTAAGATTGAAAAAGAACTGATCGATAAAGCTCGTAAG GATTTTGATGAGGAGTTTGCAGTAATTGAATCTGTAGTTAAATCATCAATTGAGCAAGAAGTTGTTGGTGCAAAAATCCA AAAAGCAAAAGGTCTTAAAAAAGGTGCTATCCTTACAAAAGAATTTTTAGCAACACTACCTTTCTCTAAATGGCTAGAAA TTTCTTTTGAGGATGAGAAACTTGAAGAGAAAGTTCAAAACGCTAGAGAGTATTATGAGGAAGCTAAAATTGCTATAGAT GCTAAATTTGAAGCTAAGAAAAAATCTATTACTCAGAGTAATGAGCTATCTCCAGGTGTGCTTAAGACTGTTAAAGTTTT TGTTGCGATTAAAAAGCGTATCCAGCCAGGTGATAAGATGGCTGGTCGTCATGGTAACAAAGGTGTGGTTTCACGCGTAT TACCAGTTGAAGATATGCCATATATGGAAGATGGTACTCCTGTAGACGTTTGTCTAAATCCTTTAGGTATCCCATCACGT ATGAACATTGGGCAGATTTTAGAAGCACACTTAGGATTGGCTTCATATGGTTTAGGTAAAAAAATCGAAAAAACTTTAGA GAAAACTAGAAAAGCAGCTGAACTAAGAAAGACTTTAGAAGAAGTATATAATAGCGTTGGCGATAAGAAAGTTAATCTTG AGGCTTTAAATGACGAAGAGATACTAACTCTTTGTGACAACCTAAAAGGTGGAGTACCAATCGCTACACCAGTATTTGAT GGTGCTAAAGAAGAAGATATTAAATCACTACTGAAAATAGGCGGCTTTGCAACTAATGGTCAGATGAAGCTTTTTGATGG TCGTACTGGTAAGCCTTTTGATAGACATGTAACTGTTGGTTATATGTATATGCTAAAACTAGATCACTTAGTAGATGATA AGATGCATGCAAGATCGACTGGCTCATATAGTCTAGTTACGCAGCAACCATTAGGTGGTAAAGCACAGTTTGGTGGACAA AGATTCGGTGAGATGGAAGTTTGGGCATTACAAGCATATGGTGCTGCTTATACATTAAGAGAGATGCTAACAGTTAAGTC AGATGACATAGCAGGTAGATCTAAAATGTATAAGAATATAGTTGATGGTAAGTTGACTATGAATGTAGATGTTCCAGAAT CATTCAATGTTTTAAGAAATGAAGTTAGAGCATTGGGTATAGATATGGATTTTGACTATTCATCTGAGGAAGAATAA Protein sequence : MSYSYAEKKRIRKEFGVLPHILDVPYLLSIQTESYKKFLTADAAKGRLHSGLEIVLKQSFPVESKNGQYELHYVDYQIGE PTFDETECQVRGATYDAPLNVKLRLVVYNKDALPNEKIVEDIREEYVYMGDIPLMTTNGTFIINGTERVVVSQLHRSPGV FFSKDDSEEGAFSARIIPYRGSWLDFEFDSKGIIWARIDRKRKFCATVILKALGYTQEQILENFSESKTITFNSKGFALR LDNLSNMKGELLKFDIVDAQDNVIVKKNKKLTSRDVKKIKDAGVDSVAIDFDLVSTLRVAKDIVNEATGEVIAYANDDVT ESLLESCVEVGMLELEVIDFITTERGRYISDTLKYDLTRNTDEALVEIYKVLRPGDPPAAASVKALFEGLFFIESRYSLS DIGRMKLNARLGSDKVSKDIYTLENSDIVGVIEELINIRDGKGKVDDIDHLGNRRVRSVGEMVENQFRIGLYRVEKGIRE SMSLVHKDKLMPKDIVNSKPITAAIKEFFTSGALSQFMDQDNPLSEVTHKRRISALGPGGLSRDRAGFEVRDVHATHYGR LCPIETPEGPNIGLINSLASYARVNDYGFLEAPYRKVVDGKVTDEIEYLSAIDEDNYVIAQASTKLDENNHFVEDLIQCR SGGEAIFTESSRVQYMDVSAKQMVSAAAALIPFLEHDDANRVLMGANMQRQAVPTLKSEKPLVGTGMEKIVARDSGNCII ARNAGEVAEVDSNRIVIKVDTEKSQTSNLVDIYSLTKFKRSNKNTCINQRPIVNVGDKVEAGDILADGFATDFGELSLGH NLMVAFMPWNGYNFEDSILLSERIVKDDKYTSIHIEEFTCVARDTKLGPEEITADIPNVSESSLAKLDESGIVHIGANVE AGDILVAKITPKAEQQLTPEERLLRAIFNEKASNVADSSLRMPSGTSGTVINVQVFENDKGGKSKRALKIEKELIDKARK DFDEEFAVIESVVKSSIEQEVVGAKIQKAKGLKKGAILTKEFLATLPFSKWLEISFEDEKLEEKVQNAREYYEEAKIAID AKFEAKKKSITQSNELSPGVLKTVKVFVAIKKRIQPGDKMAGRHGNKGVVSRVLPVEDMPYMEDGTPVDVCLNPLGIPSR MNIGQILEAHLGLASYGLGKKIEKTLEKTRKAAELRKTLEEVYNSVGDKKVNLEALNDEEILTLCDNLKGGVPIATPVFD GAKEEDIKSLLKIGGFATNGQMKLFDGRTGKPFDRHVTVGYMYMLKLDHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQ RFGEMEVWALQAYGAAYTLREMLTVKSDDIAGRSKMYKNIVDGKLTMNVDVPESFNVLRNEVRALGIDMDFDYSSEEE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| BJAB07104_00346 | YP_008207811.1 | DNA-directed RNA polymerase, beta subunit/140 kD subunit | Not tested | AbaR25 | Protein | 0.0 | 58 |
| BJAB0868_00350 | YP_008211676.1 | DNA-directed RNA polymerase, beta subunit/140 kD subunit | Not tested | AbaR26 | Protein | 0.0 | 58 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | CP001138.1.gene4362. | Protein | 0.0 | 60 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | NC_002695.1.914942.p | Protein | 0.0 | 60 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | CP000034.1.gene3741. | Protein | 0.0 | 60 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | CP000647.1.gene4402. | Protein | 0.0 | 60 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | NC_002516.2.881699.p | Protein | 0.0 | 60 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | CP001918.1.gene250.p | Protein | 0.0 | 59 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | CP000675.2.gene392.p | Protein | 0.0 | 59 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | CP004022.1.gene2794. | Protein | 0.0 | 58 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | NC_009085.4918494.p0 | Protein | 0.0 | 58 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | NC_010611.6233925.p0 | Protein | 0.0 | 58 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | NC_011595.7060572.p0 | Protein | 0.0 | 58 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | NC_010410.6003841.p0 | Protein | 0.0 | 58 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | NC_011586.7046027.p0 | Protein | 0.0 | 58 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | NC_010400.5987325.p0 | Protein | 0.0 | 58 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | CP002695.1.gene18.p0 | Protein | 0.0 | 56 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | NC_008702.1.4609796. | Protein | 0.0 | 56 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | NC_011035.1.6448762. | Protein | 0.0 | 56 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | AE016830.1.gene3155. | Protein | 0.0 | 44 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | CP003583.1.gene2745. | Protein | 0.0 | 44 |
| rpoB | YP_001121321.1 | DNA-directed RNA polymerase subunit beta | NC_012469.1.7686402. | Protein | 0.0 | 42 |
