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Name : rpoB (CGSHiGG_05825) Accession : YP_001292459.1 Strain : Haemophilus influenzae PittGG Genome accession: NC_009567 Putative virulence/resistance : Unknown Product : DNA-directed RNA polymerase subunit beta Function : - COG functional category : K : Transcription COG ID : COG0085 EC number : 2.7.7.6 Position : 1058807 - 1062745 bp Length : 3939 bp Strand : - Note : DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme DNA sequence : TTGGATTCTTTTGATAAATTTATTCAAAAAGATCCTGAAGGTCAGCAAGGTTTAGAAGCGGCATTTCGTTCTGTATTCCC TATTGTAAGCAATAATGGCTATACAGAATTACAATATGTAGATTATCGTTTAGAAGAGCCAGAGTTTGATGTACGTGAGT GCCAAATTCGTGGCTCAACTTATGCAGCAGGCTTACGTGTAAAATTACGTTTAGTGAGCTACGATAAAGAATCTTCTTCA CGCGCAGTTAAAGATATTAAAGAAAATGAAGTTTATATGGGGGAAATCCCATTAATGACTGATAACGGTACTTTTGTAAT TAATGGTACCGAGCGTGTTATCGTTTCACAATTACACCGTAGTCCGGGTGTATTCTTCGATTCTGACAAAGGTAAAACCC ATTCTTCAGGTAAAGTGCTTTATAACGCACGCATTATTCCTTACCGTGGTTCTTGGTTAGATTTTGAATTCGATCCAAAA GATAACTTATTTGCGCGCATTGACCGTCGCCGTAAATTACCAGCAACAATCATTCTTCGTGCATTAGGCTACACCACTGA AGAAATTTTAAACTTATTCTTTGATAAAATTACCTTTGAAATCGCTGGCGATAAATTGTTAATGACTTTAGTGCCAGAAC GTTTACGTGGTGAAACGGCTTCTTTTGATATTGAAGCAAATGGCAAAGTGTATGTTGAACGTGGTCGTCGCATCACTGCT CGTCACATTAAAGCATTAGAAAAAGATAATATCTCACAAGTGGTTGTGCCTTCTGAATATATTTTAGGTAAAGTTGCGTC GAAAGATTATGTTGATTTAGAGTCTGGCGAAATTATTTGTCCTGCAAATGGTGAAATTTCGTTAGAAACCCTCGCAAAAT TAGCACAAGCTGGTTACACCACGATCGAAACTTTATTTACTAATGATTTAGATTACGGTCCATATATTTCTGAAACGCTA CGTGTCGATCCAACTTATGACAAAATCAGTGCGCTTTACGAAATTTATCGTATGATGCGTCCGGGCGAGCCACCAACACC AGAATCTTCAGAAGCGTTATTCAATAATTTATTCTTCTCTGCAGAACGTTATGATTTATCTACAGTAGGTCGTATGAAGT TCAACCGTTCTTTAGCTTTTCCAGAAGGGGAAGGTGCGGGTATTTTAAGCAATGAAGATATTATTGCGGTAATGCGTAAA TTGATCGACATCCGTAATGGTCGTGGCGAAGTAGACGATATTGACCATTTGGGTAACCGTCGTATCCGTAGCGTGGGCGA AATGGCTGAAAACCAATTCCGTATCGGTTTAGTGCGTGTTGAAAGAGCGGTCAAAGAACGTCTATCTTTAGGCGATTTAG ATGCGATCACGCCACAAGACTTAATTAACCCGAAACCGATTTCTGCGGCAGTAAAAGAATTCTTTGGTTCTTCACAGCTT TCGCAATTTATGGATCAAAACAACCCATTGTCAGAAGTGACACACAAACGTCGTATTTCTGCATTAGGTCCAGGCGGTTT AACGCGTGAGCGTGCAGGCTTTGAAGTGCGTGACGTACATAATACTCACTATGGTCGTTTATGTCCGATTGAAACCCCTG AAGGTCCAAACATCGGTTTGATCAACTCACTTTCTGCTTTTGCACGTACTAATGATTATGGTTTCTTAGAAACACCATAT CGTAAAGTGGTTGATGGTCAAGTTACTGAAGAAATTGAATACTTATCTGTAATTGATGAAGCAAACTACATCATTGCACA GGCAAACTCAAACTTAGACGAAAATAACCGTTTTACTGATGCTTTCGTTACTGCTCGTGGTGAACGTGGTGAATCTGGTT TATATAAACCTGAAGATATTCACTATATGGATGTTTCGACACAACAAGTGGTATCTGTTGCGGCTGCATTAATTCCATTC CTTGAGCATGACGATGCGAACCGTGCGTTGATGGGTGCGAACATGCAACGTCAAGCAGTTCCAACATTACGTGCGGATAA ACCATTAGTTGGTACAGGTATGGAAAAACCAATCGCACTTGACTCAGGTGTTGCGGTTGTTGCAAAACGTGGTGGTACCG TTCAGTACGTTGATGCGTCTCGTATTGTGATTAAAGTAAATGAAGATGAGACTATTGCAGGTGAAGCTGGTATTGATATT TATAATTTAATTAAATACACCCGCTCTAACCAAAATACTTGTATTAACCAAATTCCTTGTGTGAATTTAGGCGATCCAAT TAATCGTGGCGAAGTATTAGCAGATGGTCCTTCAACTGATTTAGGGGAACTTGCATTAGGTCAAAATATTCGCGTAGCGT TCATGCCTTGGAACGGCTATAACTTTGAAGACTCAATGTTAGTTTCTGAACGTGTTGTTCAACAAGACCGTTTCACTACG ATCCATATTCAAGAATTATCTTGTGTTGCGCGTGATACTAAGTTAGGTGCAGAAGAAATTACTGCGGATATTCCAAACGT AGGTGAATCAGCGTTAAGCAAACTTGATGAATCTGGTATCGTTTATGTCGGTGCTGAGGTTAAAGGTGGCGACATCTTAG TAGGTAAAGTAACCCCTAAAGGCGAAACTCAATTAACCCCAGAAGAAAAATTGTTACGTGCAATCTTTGGGGAAAAAGCT TCCGATGTGAAAGATTCTTCATTACGCGTGCCAAATGGTACATCAGGTACGGTTATTGATGTTCAAGTCTTCACTCGTGA TGGCGTAGAAAAAGATAAACGTGCATTAGAAATCGAAGAAATGCAACTTCGTGAAGCGAAAAAAGATTTAACTGAAGAGT TAGAGATTTTAGAAGCTGGTTTATTTGCTCGTGTGCGTAATCTTCTTATTTCTAGTGGTGCGGATGCAGCACAATTAGAT AAAGTAGATCGCACTAAATGGTTAGAACAAACCATTGCAGATGAAGAAAAACAAAACCAATTAGAACAGCTTGCTGAGCA ATACGAAGAACTTCGTAAAGAGTTTGAACATAAACTTGAAGTGAAACGTAAGAAAATCATTAAAGGCGATGATCTTGCAC CGGGCGTATTAAAAGTTGTGAAAGTTTACCTTGCAGTGAAACGTCAAATCCAGCCGGGGGATAAAATGGCGGGTCGTCAC GGTAACAAAGGTGTTATCTCGAAAATTAACCCAGTTGAAGATATGCCATACGATGAAAATGGTCAGCCAGTTGAAATCGT ATTAAACCCACTGGGCGTACCGTCTCGTATGAACATCGGTCAGATCCTTGAAACTCACTTAGGTTTAGCTGCAAAAGGTA TTGGTGATCAAATCAATGCAATGCTTAAACAAAAACAAGAAGTGGAAAAATTACGTAGCTATATCCAAAAAGCATACGAT TTATTAGGTAATGGTTCACAAAAAGTGGATTTAAGCACTTTTACTGATGAAGAAGTATTGCGTTTAGCGGGAAATTTACG TAAAGGCTTACCAGTTGCAACGCCAGTGTTCGATGGTGCAGACGAAGCGGAAATCAAAGAACTATTAAAACTTGGTGGAT TACCAACTTCAGGTCAAATAACCCTTTACGATGGTCGTACTGGCGAGAAATTTGAACGTCCAGTAACCGTGGGTTATATG TATATGCTCAAATTGAACCACTTAGTTGATGATAAAATGCACGCTCGTTCAACAGGTTCTTATAGCCTTGTTACACAACA GCCATTGGGTGGTAAAGCACAATTTGGTGGTCAGCGTTTCGGTGAGATGGAGGTTTGGGCACTTGAAGCATATGGTGCAG CCTACACCTTACAAGAAATGCTAACTGTGAAATCCGATGATGTGAATGGTCGTACGAAGATGTATAAAAATATCGTAAGT GGCAACCAACATATGGAGCCAGGCACACCGGAATCTTTCAACGTAATTATGAAAGAAATCCGCTCACTTGGTTTAAATAT CGAGTTAGACGAAGAGTAA Protein sequence : MDSFDKFIQKDPEGQQGLEAAFRSVFPIVSNNGYTELQYVDYRLEEPEFDVRECQIRGSTYAAGLRVKLRLVSYDKESSS RAVKDIKENEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPK DNLFARIDRRRKLPATIILRALGYTTEEILNLFFDKITFEIAGDKLLMTLVPERLRGETASFDIEANGKVYVERGRRITA RHIKALEKDNISQVVVPSEYILGKVASKDYVDLESGEIICPANGEISLETLAKLAQAGYTTIETLFTNDLDYGPYISETL RVDPTYDKISALYEIYRMMRPGEPPTPESSEALFNNLFFSAERYDLSTVGRMKFNRSLAFPEGEGAGILSNEDIIAVMRK LIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLSLGDLDAITPQDLINPKPISAAVKEFFGSSQL SQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHNTHYGRLCPIETPEGPNIGLINSLSAFARTNDYGFLETPY RKVVDGQVTEEIEYLSVIDEANYIIAQANSNLDENNRFTDAFVTARGERGESGLYKPEDIHYMDVSTQQVVSVAAALIPF LEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAVVAKRGGTVQYVDASRIVIKVNEDETIAGEAGIDI YNLIKYTRSNQNTCINQIPCVNLGDPINRGEVLADGPSTDLGELALGQNIRVAFMPWNGYNFEDSMLVSERVVQQDRFTT IHIQELSCVARDTKLGAEEITADIPNVGESALSKLDESGIVYVGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKA SDVKDSSLRVPNGTSGTVIDVQVFTRDGVEKDKRALEIEEMQLREAKKDLTEELEILEAGLFARVRNLLISSGADAAQLD KVDRTKWLEQTIADEEKQNQLEQLAEQYEELRKEFEHKLEVKRKKIIKGDDLAPGVLKVVKVYLAVKRQIQPGDKMAGRH GNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGLAAKGIGDQINAMLKQKQEVEKLRSYIQKAYD LLGNGSQKVDLSTFTDEEVLRLAGNLRKGLPVATPVFDGADEAEIKELLKLGGLPTSGQITLYDGRTGEKFERPVTVGYM YMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVS GNQHMEPGTPESFNVIMKEIRSLGLNIELDEE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| BJAB07104_00346 | YP_008207811.1 | DNA-directed RNA polymerase, beta subunit/140 kD subunit | Not tested | AbaR25 | Protein | 0.0 | 69 |
| BJAB0868_00350 | YP_008211676.1 | DNA-directed RNA polymerase, beta subunit/140 kD subunit | Not tested | AbaR26 | Protein | 0.0 | 69 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | CP000034.1.gene3741. | Protein | 0.0 | 84 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | CP001138.1.gene4362. | Protein | 0.0 | 84 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | CP001918.1.gene250.p | Protein | 0.0 | 84 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | CP000647.1.gene4402. | Protein | 0.0 | 84 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | CP004022.1.gene2794. | Protein | 0.0 | 83 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | NC_002695.1.914942.p | Protein | 0.0 | 83 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | NC_002516.2.881699.p | Protein | 0.0 | 70 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | NC_009085.4918494.p0 | Protein | 0.0 | 69 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | NC_010410.6003841.p0 | Protein | 0.0 | 69 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | NC_011586.7046027.p0 | Protein | 0.0 | 69 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | NC_010400.5987325.p0 | Protein | 0.0 | 69 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | NC_010611.6233925.p0 | Protein | 0.0 | 69 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | NC_011595.7060572.p0 | Protein | 0.0 | 69 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | CP000675.2.gene392.p | Protein | 0.0 | 68 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | NC_008702.1.4609796. | Protein | 0.0 | 64 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | NC_011035.1.6448762. | Protein | 0.0 | 63 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | CP002695.1.gene18.p0 | Protein | 0.0 | 63 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | CP003583.1.gene2745. | Protein | 0.0 | 47 |
| rpoB | YP_001292459.1 | DNA-directed RNA polymerase subunit beta | AE016830.1.gene3155. | Protein | 2e-180 | 47 |
