Gene Information

Name : cysB (KPN_01271)
Accession : YP_001334934.1
Strain : Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Genome accession: NC_009648
Putative virulence/resistance : Unknown
Product : transcriptional regulator CysB
Function : -
COG functional category : K : Transcription
COG ID : COG0583
EC number : -
Position : 1426985 - 1427959 bp
Length : 975 bp
Strand : +
Note : LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes

DNA sequence : 
ATGAAACTACAACAGCTTCGCTACATCGTTGAGGTGGTTAACCATAACCTGAATGTTTCATCCACCGCCGAAGGGCTCTA
TACCTCCCAGCCGGGTATCAGTAAGCAGGTCCGCATGCTGGAGGATGAGCTGGGCATTCAGATCTTTGCCCGCAGCGGTA
AACACTTAACCCAGGTGACGCCGGCCGGGCAGGAGATCATCCGCATCGCCCGCGAAGTGCTGTCGAAAGTCGATGCCATC
AAATCTGTCGCCGGAGAGCATACCTGGCCTGACAAAGGGTCTCTTTACGTCGCCACCACCCATACCCAGGCGCGCTATGC
GTTACCGGGAGTGATCAAGGGGTTTATTGAACGCTACCCGCGGGTGTCGCTGCATATGCATCAGGGCTCGCCGACTCAGA
TTGCGGAGGCTGTGTCGAAAGGCAATGCCGATTTCGCCATCGCCACCGAGGCGCTACATCTGTATGACGATCTGGTGATG
CTGCCATGCTATCACTGGAACCGGTCGATTGTAGTGACCCCCGAGCATCCTCTGGCCACCAAGGGCTCGGTGTCCATAGA
GGAACTGGCCCAGTATCCATTGGTAACCTATACCTTTGGTTTTACCGGCCGCTCCGAACTGGATACCGCGTTTAACCGTG
CGGGCCTGACGCCGCGCATTGTTTTTACCGCCACCGATGCCGACGTCATCAAAACCTATGTTCGCCTGGGGCTGGGGGTA
GGGGTAATCGCCAGCATGGCGGTGGATCCGGTCTCTGACCCGGATCTGGTGAAGCTGGATGCGAACGGTATTTTCAGCCA
CAGCACCACTAAGATAGGTTTCCGCCGTAGCACCTTCTTACGAAGCTACATGTATGATTTTATTCAACGTTTTGCTCCCC
ATTTGACCAGGGACGTGGTAGATACCGCGGTGGCTTTACGCTCGAATGAAGATATTGAAGCGATGTTCAAAGATATAAAA
CTTCCGGAAAAATAA

Protein sequence : 
MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDELGIQIFARSGKHLTQVTPAGQEIIRIAREVLSKVDAI
KSVAGEHTWPDKGSLYVATTHTQARYALPGVIKGFIERYPRVSLHMHQGSPTQIAEAVSKGNADFAIATEALHLYDDLVM
LPCYHWNRSIVVTPEHPLATKGSVSIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTPRIVFTATDADVIKTYVRLGLGV
GVIASMAVDPVSDPDLVKLDANGIFSHSTTKIGFRRSTFLRSYMYDFIQRFAPHLTRDVVDTAVALRSNEDIEAMFKDIK
LPEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cbl YP_853089.1 transcriptional regulator Cbl Not tested PAI IV APEC-O1 Protein 1e-58 41