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Name : apxIIA (APJL_0967) Accession : YP_001651969.1 Strain : Actinobacillus pleuropneumoniae JL03 Genome accession: NC_010278 Putative virulence/resistance : Virulence Product : hemolysin A Function : - COG functional category : P : Inorganic ion transport and metabolism COG ID : COG3487 EC number : - Position : 1059850 - 1062720 bp Length : 2871 bp Strand : - Note : - DNA sequence : ATGTCAAAAATCACTTTGTCATCATTAAAATCGTCCTTACAACAAGGATTGAAAAATGGGAAAAACAAGTTAAATCAAGC AGGTACAACACTGAAGAATGGTTTAACTCAAACTGGTCATTCTCTACAGAATGGGGCTAAAAAATTAATCTTATATATTC CTCAAGGCTATGATTCGGGTCAAGGAAATGGAGTTCAAGATTTAGTTAAAGCTGCTAATGATTTAGGTATTGAAGTATGG CGAGAAGAACGCAGCAATTTGGACATTGCAAAAACTAGCTTTGATACAACTCAGAAAATTCTAGGTTTTACTGATAGAGG AATTGTATTATTTGCACCTCAGCTAGATAATTTATTAAAGAAGAATCCTAAAATTGGCAATACATTAGGAAGTGCTTCTA GCATCTCACAAAATATAGGTAAAGCCAATACTGTATTAGGTAGTATTCAATCTATTTTAGGATCTGTTTTATCTGGAGTA AATCTGAATGAATTACTTCAAAATAAAGATCCTAATCAATTAGAACTTGCAAAAGCAGGGCTAGAACTGACTAATGAATT AGTTGGTAATATTGCTAGCTCGGTGCAAACTGTAGATGCATTTGCAGAACAAATATCTAAACTAGGTTCACATTTACAGA ATGTGAAAGGATTAGGAGGATTGAGTAATAAATTACAAAATCTACCAGATCTAGGAAAAGCAAGTTTAGGTTTGGACATT ATCTCTGGTTTACTTTCTGGAGCATCTGCAGGTCTCATTTTAGCAGATAAAGAGGCTTCAACAGAAAAGAAAGCTGCCGC AGGTGTAGAATTTGCTAACCAAATTATAGGTAATGTAACAAAAGCGGTCTCATCTTACATTCTTGCCCAACGAGTCGCTT CAGGTTTGTCTTCAACTGGTCCTGTCGCTGCATTAATCGCATCTACAGTTGCACTAGCTGTTAGCCCTCTTTCATTCTTA AATGTAGCTGATAAGTTTAAACAAGCTGATTTAATCAAATCATATTCTGAACGCTTCCAAAAATTAGGATATGATGGAGA TCGTTTATTAGCTGATTTTCACCGTGAGACAGGAACTATTGATGCTTCTGTAACAACAATTAACACTGCTTTAGCAGCTA TCTCCGGTGGAGTTGGAGCTGCAAGCGCGGGTTCTCTAGTCGGAGCTCCAGTTGCGTTACTCGTTGCTGGTGTTACGGGA CTTATTACAACTATTCTAGAATATTCTAAACAAGCCATGTTTGAACATGTTGCAAATAAGGTTCATGACAGAATAGTTGA ATGGGAGAAAAAACATAATAAAAACTATTTTGAGCAAGGTTATGATTCTCGTCATTTAGCTGATTTACAAGACAATATGA AGTTTCTTATCAATTTAAATAAAGAACTTCAGGCTGAACGCGTAGTAGCTATTACCCAACAAAGATGGGATAACCAAATT GGAGACCTAGCGGCAATTAGCCGTAGAACGGATAAAATTTCCAGTGGAAAAGCTTATGTGGATGCTTTTGAGGAGGGGCA ACACCAGTCCTACGATTCATCCGTACAGCTAGATAACAAAAACGGTATTATTAATATTAGTAATACAAATAGAAAGACAC AAAGTGTTTTATTCAGAACTCCATTACTAACTCCAGGTGAAGAGAATCGGGAACGTATTCAGGAAGGTAAAAATTCTTAT ATTACAAAATTACATATACAAAGAGTTGACAGTTGGACTGTAACAGATGGTGATGCTAGCTCAAGCGTAGATTTCACTAA TGTAGTACAACGAATCGCTGTGAAATTTGATGATGCAGGTAACATTATCGAATCTAAAGATACTAAAATTATCGCAAATT TAGGTGCTGGTAACGATAATGTATTTGTTGGGTCAAGTACTACCGTTATTGATGGCGGGGACGGACATGATCGAGTTCAC TACAGTAGAGGAGAATATGGCGCATTAGTTATTGATGCTACAGCCGAGACAGAAAAAGGCTCATATTCAGTAAAACGCTA TGTCGGAGACAGTAAAGCATTACATGAAACAATTGCCACCCACCAAACAAATGTTGGTAATCGTGAAGAAAAAATTGAAT ATCGTCGTGAAGATGATCGTTTTCATACTGGTTATACTGTGACGGACTCACTCAAATCAGTTGAAGAGATCATTGGTTCA CAATTTAATGATATTTTCAAAGGAAGCCAATTTGATGATGTGTTCCATGGTGGTAATGGTGTAGACACTATTGATGGTAA CGATGGTGACGATCATTTATTTGGTGGCGCAGGCGATGATGTTATCGATGGAGGAAACGGTAACAATTTCCTTGTTGGAG GAACCGGTAATGATATTATCTCGGGAGGTAAAGATAATGATATTTATGTCCATAAAACAGGCGATGGAAATGATTCTATT ACAGACTCTGGCGGACAAGATAAACTGGCATTTTCGGATGTAAATCTTAAAGACCTCACCTTTAAGAAAGTAGATTCTTC TCTCGAAATCATTAATCAAAAAGGAGAAAAAGTTCGTATTGGGAATTGGTTCTTAGAAGATGATTTGGCTAGCACAGTTG CTAACTATAAAGCTACGAATGACCGAAAAATTGAGGAAATTATTGGTAAAGGAGGAGAACGTATTACATCAGAACAAGTT GATAAACTGATTAAGGAGGGTAACAATCAAATCTCTGCAGAAGCATTATCCAAAGTTGTGAATGATTACAATACGAGTAA AGATAGACAGAACGTATCTAATAGCTTAGCAAAATTGATTTCTTCAGTCGGGAGCTTTACGTCTTCCTCAGACTTTAGGA ATAATTTAGGAACATATGTTCCTTCATCAATAGATGTCTCGAATAATATTCAATTAGCTAGAGCCGCTTAA Protein sequence : MSKITLSSLKSSLQQGLKNGKNKLNQAGTTLKNGLTQTGHSLQNGAKKLILYIPQGYDSGQGNGVQDLVKAANDLGIEVW REERSNLDIAKTSFDTTQKILGFTDRGIVLFAPQLDNLLKKNPKIGNTLGSASSISQNIGKANTVLGSIQSILGSVLSGV NLNELLQNKDPNQLELAKAGLELTNELVGNIASSVQTVDAFAEQISKLGSHLQNVKGLGGLSNKLQNLPDLGKASLGLDI ISGLLSGASAGLILADKEASTEKKAAAGVEFANQIIGNVTKAVSSYILAQRVASGLSSTGPVAALIASTVALAVSPLSFL NVADKFKQADLIKSYSERFQKLGYDGDRLLADFHRETGTIDASVTTINTALAAISGGVGAASAGSLVGAPVALLVAGVTG LITTILEYSKQAMFEHVANKVHDRIVEWEKKHNKNYFEQGYDSRHLADLQDNMKFLINLNKELQAERVVAITQQRWDNQI GDLAAISRRTDKISSGKAYVDAFEEGQHQSYDSSVQLDNKNGIINISNTNRKTQSVLFRTPLLTPGEENRERIQEGKNSY ITKLHIQRVDSWTVTDGDASSSVDFTNVVQRIAVKFDDAGNIIESKDTKIIANLGAGNDNVFVGSSTTVIDGGDGHDRVH YSRGEYGALVIDATAETEKGSYSVKRYVGDSKALHETIATHQTNVGNREEKIEYRREDDRFHTGYTVTDSLKSVEEIIGS QFNDIFKGSQFDDVFHGGNGVDTIDGNDGDDHLFGGAGDDVIDGGNGNNFLVGGTGNDIISGGKDNDIYVHKTGDGNDSI TDSGGQDKLAFSDVNLKDLTFKKVDSSLEIINQKGEKVRIGNWFLEDDLASTVANYKATNDRKIEEIIGKGGERITSEQV DKLIKEGNNQISAEALSKVVNDYNTSKDRQNVSNSLAKLISSVGSFTSSSDFRNNLGTYVPSSIDVSNNIQLARAA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hlyA | NP_755445.1 | hemolysin A | Virulence | PAI I CFT073 | Protein | 7e-150 | 49 |
| hlyA | CAD33759.1 | hemolysin A | Virulence | PAI I 536 | Protein | 6e-147 | 49 |
| hlyA | CAD42039.1 | HlyA protein | Virulence | PAI II 536 | Protein | 3e-148 | 48 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| apxIIA | YP_001651969.1 | hemolysin A | VFG1500 | Protein | 4e-147 | 49 |
| apxIIA | YP_001651969.1 | hemolysin A | VFG0906 | Protein | 3e-150 | 49 |
| apxIIA | YP_001651969.1 | hemolysin A | VFG1558 | Protein | 2e-148 | 48 |
| apxIIA | YP_001651969.1 | hemolysin A | VFG0840 | Protein | 4e-146 | 45 |
