Gene Information

Name : rpoB (Bcenmc03_0319)
Accession : YP_001763621.1
Strain :
Genome accession: NC_010508
Putative virulence/resistance : Unknown
Product : DNA-directed RNA polymerase subunit beta
Function : -
COG functional category : K : Transcription
COG ID : COG0085
EC number : -
Position : 357803 - 361909 bp
Length : 4107 bp
Strand : +
Note : DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme

DNA sequence : 
ATGCAATATTCCTTCACCGAGAAGAAGCGCATTCGCAAGAGTTTCGCGAAGCGCCCCATCGTTCACCAAGTTCCGTTCTT
GCTGGCTACCCAGCTTGAATCATTCAGCACGTTTCTGCAAGCCGATGTGCCCGCGACGCAACGTAAGCCTGAGGGTTTGC
AGGCCGCGTTCACATCGGTATTTCCCATTGTTTCGCACAACGGTTTCGCGCGCCTCGAGTTCGTGAGCTATGCGCTGTCC
TCGCCGGCATTCAACATCAAGGAATGCCAGCAGCGGGGCCTGACGTACTGCTCCGCGCTGCGCGCGAAGGTCCGCCTCGT
CATCCTCGACAAGGAATCGCCGAACAAGCCGGTCGTCAAGGAAGTGAAGGAGCAGGAAGTGTACATGGGCGAAATTCCGC
TCATGACGCCGACGGGCTCGTTCGTCATCAACGGCACCGAGCGTGTCATCGTCTCGCAGCTGCACCGTTCGCCGGGCGTG
TTTTTCGAACACGACAAGGGCAAGACGCACAGCTCGGGCAAGCTGCTGTTCTCGGCACGGATCATTCCGTACCGCGGCTC
GTGGCTCGACTTCGAATTCGATCCGAAGGACATCCTGTACTTCCGCGTCGACCGTCGCCGCAAGATGCCGGTCACGATCC
TGCTGAAGGCCATCGGCCTGACGCCGGAACAGATCCTCGCGAACTTCTTCGTGTTCGACAACTTCACGCTGATGGACGAA
GGCGCGCAACTCGAGTTCGTGCCCGAGCGCCTGCGTGGTGAAGTCGCGCGTTTCGACATCACGGATCGCGACGGCAAGGT
CATCGTCCAGAAGGACAAGCGGATCAACGCGAAGCACATTCGCGACCTCGAAGCCGCGAAGACCAAGTTCATCTCGGTGC
CGGAAGACTATCTGCTCGGCCGCGTGCTGGCGAAGAACGTCGTCGACGGCGATACCGGCGAAGTGATCGCGAGCGCGAAC
GACGAAGTCACGGAAAGCGTGCTCGAGAAGCTGCGCGAAGCGGGCATCAAGGACATCCAGACGCTCTACACGAACGATCT
GGACCAGGGCCCGTACATCTCGTCGACGCTGCGTGTCGACGAAACGACCGACAAGACGGCCGCGCGCATCGCGATCTACC
GCATGATGCGTCCGGGCGAGCCGCCGACCGAAGAAGCGGTCGAGGCCCTGTTCAACCGTCTGTTCTACAGCGAAGAAGCG
TACGACCTGTCGAAGGTCGGCCGCATGAAGTTCAACCGCCGCGTCGGCCGTGACGAGATCGTCGGCCCGATGACGCTGCA
GGACGACGACATCCTCGCGACGATCAAGATCCTCGTCGAGCTGCGCAACGGCAAGGGCGAAGTGGACGACATCGACCACC
TCGGCAACCGTCGCGTGCGTTGCGTCGGCGAACTGGCGGAAAACCAGTTCCGCGCGGGTCTCGTGCGTGTCGAGCGCGCA
GTCAAGGAACGCCTCGGCCAGGCCGAAAGCGAAAACCTGATGCCGCACGACCTGATCAACTCGAAGCCGATTTCGTCGGC
GATCCGCGAGTTCTTCGGTTCGTCGCAGCTGTCGCAGTTCATGGACCAGACCAACCCGCTGTCGGAAATCACGCACAAGC
GCCGTGTTTCCGCACTGGGCCCGGGCGGTCTGACCCGCGAACGCGCAGGCTTCGAAGTCCGCGACGTGCACCCGACCCAC
TACGGCCGCGTGTGCCCGATCGAAACGCCGGAAGGTCCGAACATCGGCCTGATCAACTCGCTCGCACTGTACGCGCACCT
GAACGAGTACGGCTTCCTCGAGACGCCGTACCGCAAGGTCGTGGACAGCAAGGTGACCGACCAGATCGACTACCTGTCGG
CGATCGAGGAAGGCCGCTACATGATCGCCCAGGCGAACGCCGCGATCGACGAGAACGGCCAGCTGATCGACGAACTCGTG
TCGTCGCGTGAAGCCGGCGAAACGATGATGGTCACGCCGGACCGGATCCAGTACATGGACGTCGCGCCGTCGCAGATCGT
GTCGGTGGCAGCCTCGCTGATCCCGTTCCTCGAGCACGATGACGCGAACCGTGCACTGATGGGTTCGAACATGCAGCGTC
AGGCCGTGCCGTGTCTGCGTCCGGAAAAGCCAGTCGTCGGTACGGGCATCGAGCGCACCTGCGCGGTCGACTCGGGTACG
ACGGTCCAGGCGTTCCGCGGCGGTGTGGTCGACTACGTCGACGCAGGTCGTATCGTGATTCGCGTGAACGACGACGAAGC
GGTCGCGGGTGAAGTCGGTGTCGACATCTACAACCTGATCAAGTACACGCGTTCGAACCAGAACACGAACATCAACCAGC
GTCCGATCGTGAAGATGGGCGACAAGGTCTCGCGCGGCGACGTGCTGGCCGACGGCGCCTCGACGGACCTGGGCGAGCTC
GCGCTCGGCCAGAACATGCTGATCGCGTTCATGCCGTGGAACGGCTACAACTTCGAAGATTCGATCCTGATCTCGGAGAA
GGTGGTCGCGGACGATCGCTACACGTCGATCCACATCGAAGAGCTGAACGTCGTTGCACGCGACACGAAGCTCGGGCCGG
AAGAAATCACGCGCGACATCTCGAACCTGGCGGAAGTCCAGCTCGGCCGTCTCGACGAATCGGGCATCGTGTACATCGGT
GCTGAAGTCGAAGCAGGCGACGTGCTGGTCGGCAAGGTCACGCCGAAGGGCGAGACCCAGCTGACGCCGGAAGAGAAGCT
GCTGCGCGCGATCTTCGGCGAGAAGGCTTCGGACGTGAAGGACACGTCGCTGCGCGTGCCGTCGGGCATGAGCGGCACCG
TGATCGACGTCCAGGTGTTCACGCGTGAAGGCATCCAGCGCGACAAGCGTGCGCAACAGATCATCGACGACGAACTGAAG
CGCTACCGTCTCGACCTGAACGACCAGCTGCGCATCGTGGAAGGCGACGCGTTCCAGCGTCTGGCACGCATGCTCGTGGG
CAAGGTCGCGAACGGCGGTCCGAAGAAGCTCGCGAAGGGCACGAAGATCGACCAGGCTTACCTGGAAGACCTCGACCACT
ACCACTGGTTCGACATCCGCCTCGCGGACGACGAAGCAGCGGCGCAGCTCGAAGCGATCAAGAACTCGATCGAAGAGAAG
CGTCACCAGTTCGATCTCGCGTTCGAAGAGAAGCGCAAGAAGCTCACGCAAGGCGACGAACTGCCGCCGGGCGTGCTGAA
GATGGTCAAGGTGTACCTCGCGGTGAAGCGCCGTCTGCAGCCTGGCGACAAGATGGCAGGCCGTCACGGTAACAAGGGTG
TCGTGTCGAAGATCGTCCCGATCGAAGACATGCCGTACATGGCCGACGGCCGTCCGGCAGACGTCGTGCTGAACCCGCTC
GGCGTGCCGTCGCGGATGAACGTGGGTCAGGTTCTGGAAGTGCACCTCGGCTGGGCCGCGAAGGGCCTCGGCTGGCGTAT
CGGCGAAATGCTGCAGCGTCAGGCGAAGATCGAGGAACTGCGCACGTTCCTGACGAAGATCTACAACGAGTCGGGCCGCC
AGGAAGATCTGGAAAGCTTCACCGACGACGAGATCCTCGAACTCGCGAAGAACCTGCGCGAAGGCGTGCCGTTCGCGACG
CCGGTGTTCGACGGTGCGACCGAGGAAGAAATGGGCAAGATGCTCGACCTCGCGTTCCCGGACGACATCGCCGAACAGCT
CGGCATGAACCCGTCGAAGAACCAGGTCCGCCTGTACGACGGCCGCACGGGCGAAATGTTCGAACGTCGCGTGACGCTCG
GCTACATGCACTACCTGAAGCTGCACCACTTGGTCGACGACAAGATGCACGCGCGTTCGACCGGCCCGTACTCGCTCGTC
ACGCAGCAGCCGCTGGGTGGTAAGGCGCAGTTCGGTGGCCAGCGTTTCGGTGAAATGGAAGTGTGGGCGCTCGAAGCGTA
CGGCGCGTCCTACGTGCTGCAGGAAATGCTGACGGTGAAGTCGGACGACGTGACCGGCCGGACGAAGGTGTACGAAAACC
TCGTCAAGGGCGATCACGTGATCGATGCAGGCATGCCGGAATCCTTCAACGTGCTCGTGAAGGAAATCCGCTCGCTCGGT
ATCGATATCGATCTCGACCGCAATTAA

Protein sequence : 
MQYSFTEKKRIRKSFAKRPIVHQVPFLLATQLESFSTFLQADVPATQRKPEGLQAAFTSVFPIVSHNGFARLEFVSYALS
SPAFNIKECQQRGLTYCSALRAKVRLVILDKESPNKPVVKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGV
FFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKAIGLTPEQILANFFVFDNFTLMDE
GAQLEFVPERLRGEVARFDITDRDGKVIVQKDKRINAKHIRDLEAAKTKFISVPEDYLLGRVLAKNVVDGDTGEVIASAN
DEVTESVLEKLREAGIKDIQTLYTNDLDQGPYISSTLRVDETTDKTAARIAIYRMMRPGEPPTEEAVEALFNRLFYSEEA
YDLSKVGRMKFNRRVGRDEIVGPMTLQDDDILATIKILVELRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERA
VKERLGQAESENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTH
YGRVCPIETPEGPNIGLINSLALYAHLNEYGFLETPYRKVVDSKVTDQIDYLSAIEEGRYMIAQANAAIDENGQLIDELV
SSREAGETMMVTPDRIQYMDVAPSQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPVVGTGIERTCAVDSGT
TVQAFRGGVVDYVDAGRIVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPIVKMGDKVSRGDVLADGASTDLGEL
ALGQNMLIAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELNVVARDTKLGPEEITRDISNLAEVQLGRLDESGIVYIG
AEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGIQRDKRAQQIIDDELK
RYRLDLNDQLRIVEGDAFQRLARMLVGKVANGGPKKLAKGTKIDQAYLEDLDHYHWFDIRLADDEAAAQLEAIKNSIEEK
RHQFDLAFEEKRKKLTQGDELPPGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPIEDMPYMADGRPADVVLNPL
GVPSRMNVGQVLEVHLGWAAKGLGWRIGEMLQRQAKIEELRTFLTKIYNESGRQEDLESFTDDEILELAKNLREGVPFAT
PVFDGATEEEMGKMLDLAFPDDIAEQLGMNPSKNQVRLYDGRTGEMFERRVTLGYMHYLKLHHLVDDKMHARSTGPYSLV
TQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVTGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLG
IDIDLDRN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00350 YP_008211676.1 DNA-directed RNA polymerase, beta subunit/140 kD subunit Not tested AbaR26 Protein 0.0 66
BJAB07104_00346 YP_008207811.1 DNA-directed RNA polymerase, beta subunit/140 kD subunit Not tested AbaR25 Protein 0.0 66

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta CP002695.1.gene18.p0 Protein 0.0 82
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_008702.1.4609796. Protein 0.0 77
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_011035.1.6448762. Protein 0.0 74
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_002516.2.881699.p Protein 0.0 68
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta CP001918.1.gene250.p Protein 0.0 66
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta CP001138.1.gene4362. Protein 0.0 66
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_002695.1.914942.p Protein 0.0 66
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta CP000034.1.gene3741. Protein 0.0 66
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_009085.4918494.p0 Protein 0.0 66
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta CP000647.1.gene4402. Protein 0.0 66
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_010611.6233925.p0 Protein 0.0 66
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_011595.7060572.p0 Protein 0.0 66
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_010410.6003841.p0 Protein 0.0 66
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_011586.7046027.p0 Protein 0.0 66
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_010400.5987325.p0 Protein 0.0 66
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta CP000675.2.gene392.p Protein 0.0 66
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta CP004022.1.gene2794. Protein 0.0 65
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta AM180355.1.gene120.p Protein 0.0 46
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_009782.5559150.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_002951.3236234.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_002953.2862188.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_007793.3914836.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_003923.1002608.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_013450.8613267.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_009641.5330265.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_002758.1120515.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_010079.5776819.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_009487.5169226.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_007622.3792928.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_002745.1123305.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_007795.3920377.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_009632.5315067.p0 Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta AE016830.1.gene3155. Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta CP003583.1.gene2745. Protein 0.0 45
rpoB YP_001763621.1 DNA-directed RNA polymerase subunit beta NC_012469.1.7686402. Protein 7e-176 43