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Name : rpoB (Amuc_1041) Accession : YP_001877648.1 Strain : Akkermansia muciniphila ATCC BAA-835 Genome accession: NC_010655 Putative virulence/resistance : Unknown Product : DNA-directed RNA polymerase subunit beta Function : - COG functional category : K : Transcription COG ID : COG0085 EC number : - Position : 1242515 - 1246453 bp Length : 3939 bp Strand : - Note : DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme DNA sequence : ATGTCAAAGCGACTCTACTTCGGGAATATCAAGGAAGTCATCGAACCTCCGAACCTTATTGAGATTCAACTTCAATCATA CTTCGATTTTCTACAACAGGACACGCCGGCCGCGGCCAGGAAAAACATCGGGTTACAAGGCGTTCTGAAGGAAATCTTTC CTATCAAGAGCTATGACGAAAACATTGAGCTCGACTTCGTCTCCTATGACATTGAACAGCCGAAGATGAGCGATTACGAG GCCATCCGCGCGGGGGAAACCTACAGCGCCGCCCTTCAGGTCACCTTCAAGCTCAAATCCGACAACGAGTCCAAGGAAGA AACGGTCTATATGGGAGAACTCCCTATGATGACCAACCGCGGCACCTTTGTCATTAACGGCGCCGAACGCGTCATTGTGT CCCAGCTGCACCGTTCCCCGGGCATTTGCTTTGAAAGCGCCCAGCATCTGAACGGAAAACTGCTCCACTCCTTCCGCATC ATCCCGGACCGGGGCTCCTGGCTGGAGGTCCAGTTTGACACCAACGACCTGCTTTACGTTTACCTTGACCGCCGCCGCCG CCGCCGCAAATTCCTTGCGACGACGTTTATGCGCTACCTGGGCTTCAAAACGGACCGTGACATCGTCAGCCAGTTCTACA ACATCCGCACGCTTCCCCTGAGCGAAGACATGACGGAAGAAGATCTGCACAACCTTGTGGCTGTGGACACGATCAAGGAC AAGGACCTGGTTCTTGCCAAGGCTTTCGAACAGCTCAATATGGGTGTGGTTCGCCAGCTCCTCCAGTTCGGCATCAAGAA AATCGACGTCATTGACCAGAGCGAGGACGACGTGCTGATCAAAACCCTGAAGAAGGATCCCGCTCACGACGAAGAATCCG CCCTCAAGGAAATCTACAAACGCCTGCGTCCCGGAGATCCCGCTACTGCCGCTCAGGCACGCACCCTGCTTAAGAGGCTT TTTGACGATCCCAAGAAATACGACCTCACCCGCGTGGGGCGCTACAAAATCAACCAGAAACTCGGGCTGGACACCAGCCT GGACCAGCGCCTGATGACGGCGGAAGATTTCCTGGCCGCCCTCAAATACCTCCTGCGCCTCAAGAAGGGCGAAGGCATGG TGGACGACATCGACCACCTGGGCAGCCGCCGCGTACGTGCCGTAGGCGAACTCATGGCCAATCAATGCCGCGTAGGCCTT GCCCGCACCGAGCGCTTGGTCAAGGAACGCATGACCCTCATTGACCAGAACATTGAAGGCGTCACGCCCAGCAAACTCAT CAATCCGAAGGCCCTCAGCGCCGTCGTGCGCGACTTCTTCGGCCGCTCCCAGCTCTCCCAATTCATGGACCAGATCAACC CCCTCGCGGAATTGACGCACAAGCGCCGTCTTTCCGCCCTGGGGCCCGGCGGCCTGAACCGTGACCGGGCCGGATTTGAA GTCCGGGACGTACACCCCTCCCACTACGGGCGCATTTGCCCCATTGAAACGCCGGAAGGTCCCAACATCGGCCTGATCAA CTCCATGTGTACCTACGCCCGCATCAATGAATTCGGATTCATTGAAACACCTTACCGCAAGGTGGAAAACGGCAGGGTCA CCAATACCATCGAATACGTCACCGCCGATCAGGAAGAAGGCTATCTCATCGCCCAGGCCAATAACCCGCTGGACGAACAG GGCAACTTCACGACCTCCCGCGTAACCGCCCGTGAAAAAGGCGAATTCATCGAAGTGGATCCGGCAGACGTGCATTACAT GGACGTTTCTCCCAAGCAGCTCGTTTCTATCGCCGCCGGTCTTATCCCCTTCCTGGAACATGACGACGCCAACCGCGCCC TGATGGGCTCCAACATGCAGCGCCAGGGCGTGCCTCTGATGGTAGCGGAATCTCCATACGTGGGAACCGGCATCGAAGGA AAGTGCGCCAGGGACTCCCGTTCCGTCGTTCTGGCGGAAGCGGACGGCATCGTGGCCTCCGCCACGGCTGAAGTCATTAT CACCACGAAAGACGGGGAACTGCCCGTGCGTCCGGAAGTATTCCTGTCCGATCCCGACAGTGTGCGCACGGACCGCGACA ATGGCGTTTACGTCTATCCCCTGCGCAAGTTCATGCGTTCCAATGCTGGAACCTGCATCAACCAGCGTCCGATCGTGCGC CGCGGCGACAAAATCAAAACCGGCGACGTGCTGGCGGACGGCCCGAACACGGACCAGGGCGAACTGGCCCTCGGCCGCAA TGTTCTGGTGGCCTATATGCCGTGGAACGGTTACAACTTCGAAGACGCTATTGTCATCTCCGAAAAAACCGTGAAGGAAG ACACCTTCACTTCCATTCATATCTCCGAGTTTGAAGTTCAGGCCCGTGACACCAAGCTGGGTCCGGAAGAAATCACCCGT GATATCCCGAACGCCGGTGATGAAGCCCTGAAAAACCTGGATCATGACGGCGTCATCCGCATCGGCGCGGAAGTGAAGCC CGGCGACATCCTCGTCGGCAAAATCACCCCCAAATCGGAAACGGAACTGGCTCCGGAAGAACGTCTCCTCCGCGCCATTT TCGGTGAAAAGGCCGCAGAAGTGAAAGATACCTCACTCCGTGTCCCCTCCGGCTGCACCGGCATCGTGATGGATGTGCGC ATTTCTTCCACAGGCTCCGGCCACCACCGCGGCGACCTCGTCGTAGACAGCGCGGAAAAGAAAAAGCAGTTCAAGAAAAT CAACGACGAACATAAAAAGAAGAAGGAGCAGCTCATTGACCAGTTGACCAAGAAGCTCTCCGATATTCTTCTGGGTGAAA AAATCCCGCTGGACGTCGTCAATGAACAGACCGGTGAAATCATCATCCCGGCCAACAGGAAAATCACCAAGACCCTGTTG CGTAAACTGGCCCTGGTTCACGACCACATCGAAATCGAACCCAGCCCGATTCGCAACAAGATTCTGGAAATCATCACTTC GTTTGAAGGCCGCTTTACGGAACTGGATGACGAACGGGAACACAGGCTGGATCAGATGGAATCCGGGGACGAATCCGAAC CCGGCGGACTGAAGGAAGTTAAAGTATATATCGCCGCCAAGCGCAAGCTCGGCGTGGGTGACAAGATGGCCGGTCGCCAC GGCAACAAAGGCGTCGTTGCCAAAATCGTCCCGGAACAGGATATGCCCTTCCTCGCGGACGGTACTCCGGTGGATATCGT TCTGAACCCCTTGGGCGTGCCTTCCCGAATGAATGTGGGGCAGGTGCTTGAAGCCCACCTCGGCATCGCTGCCAGGGCCC TTGGCTTCAAGGTGGCTACCCCGGTGTTCGACGGGATCAGTGAAGAAACCATCTGGAATTACATGTCCGAAGCCAAGAAG GTGGACGGTTTCACCTGGATCGGTGACGGCAAGGACGGCACCGTGGGAGGGAAGAGTACCCTTTATGACGGCCTGACCGG CGAACCTTTCCATAACCCGGTGGTGGTAGGCCAGACCTACATGCTCAAACTGAACCACCTGGTGGCGGACAAGATTCACG CCCGCGCCGTGGGTCCGTACAGCCTGGTCACGCAGCAGCCTCTGGGCGGCAAGGCCCAATACGGCGGTCAGCGTTTCGGG GAAATGGAAGTGTGGGCACTGGAAGCCTATGGCGCCGCCTATACCCTCCAGGAACTTCTCACCGTCAAGTCCGACGACGT TCAGGGCCGTACCCGCATTTACGAATCCATCGTGAAGGGGGATAATACCCTGGAAGCCGGAACTCCGGAATCTTTCAACG TTCTGATGAAGGAAATGCAGTCCCTGGGGCTGAACGTACGCCCCGGCAGCAAGGATGAACAACCCTCCCTGCAACTCGGC GGCACGGATCTCACTCCCGTGGACGGCATGACGGAAGGCTTTGACAGCGACGACATGGCCGGCCTGGCGGACGTCGACTT CTCCGACCTCAAATTCTAA Protein sequence : MSKRLYFGNIKEVIEPPNLIEIQLQSYFDFLQQDTPAAARKNIGLQGVLKEIFPIKSYDENIELDFVSYDIEQPKMSDYE AIRAGETYSAALQVTFKLKSDNESKEETVYMGELPMMTNRGTFVINGAERVIVSQLHRSPGICFESAQHLNGKLLHSFRI IPDRGSWLEVQFDTNDLLYVYLDRRRRRRKFLATTFMRYLGFKTDRDIVSQFYNIRTLPLSEDMTEEDLHNLVAVDTIKD KDLVLAKAFEQLNMGVVRQLLQFGIKKIDVIDQSEDDVLIKTLKKDPAHDEESALKEIYKRLRPGDPATAAQARTLLKRL FDDPKKYDLTRVGRYKINQKLGLDTSLDQRLMTAEDFLAALKYLLRLKKGEGMVDDIDHLGSRRVRAVGELMANQCRVGL ARTERLVKERMTLIDQNIEGVTPSKLINPKALSAVVRDFFGRSQLSQFMDQINPLAELTHKRRLSALGPGGLNRDRAGFE VRDVHPSHYGRICPIETPEGPNIGLINSMCTYARINEFGFIETPYRKVENGRVTNTIEYVTADQEEGYLIAQANNPLDEQ GNFTTSRVTAREKGEFIEVDPADVHYMDVSPKQLVSIAAGLIPFLEHDDANRALMGSNMQRQGVPLMVAESPYVGTGIEG KCARDSRSVVLAEADGIVASATAEVIITTKDGELPVRPEVFLSDPDSVRTDRDNGVYVYPLRKFMRSNAGTCINQRPIVR RGDKIKTGDVLADGPNTDQGELALGRNVLVAYMPWNGYNFEDAIVISEKTVKEDTFTSIHISEFEVQARDTKLGPEEITR DIPNAGDEALKNLDHDGVIRIGAEVKPGDILVGKITPKSETELAPEERLLRAIFGEKAAEVKDTSLRVPSGCTGIVMDVR ISSTGSGHHRGDLVVDSAEKKKQFKKINDEHKKKKEQLIDQLTKKLSDILLGEKIPLDVVNEQTGEIIIPANRKITKTLL RKLALVHDHIEIEPSPIRNKILEIITSFEGRFTELDDEREHRLDQMESGDESEPGGLKEVKVYIAAKRKLGVGDKMAGRH GNKGVVAKIVPEQDMPFLADGTPVDIVLNPLGVPSRMNVGQVLEAHLGIAARALGFKVATPVFDGISEETIWNYMSEAKK VDGFTWIGDGKDGTVGGKSTLYDGLTGEPFHNPVVVGQTYMLKLNHLVADKIHARAVGPYSLVTQQPLGGKAQYGGQRFG EMEVWALEAYGAAYTLQELLTVKSDDVQGRTRIYESIVKGDNTLEAGTPESFNVLMKEMQSLGLNVRPGSKDEQPSLQLG GTDLTPVDGMTEGFDSDDMAGLADVDFSDLKF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| BJAB07104_00346 | YP_008207811.1 | DNA-directed RNA polymerase, beta subunit/140 kD subunit | Not tested | AbaR25 | Protein | 0.0 | 50 |
| BJAB0868_00350 | YP_008211676.1 | DNA-directed RNA polymerase, beta subunit/140 kD subunit | Not tested | AbaR26 | Protein | 0.0 | 50 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | NC_009085.4918494.p0 | Protein | 0.0 | 50 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | NC_010410.6003841.p0 | Protein | 0.0 | 50 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | NC_011586.7046027.p0 | Protein | 0.0 | 50 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | NC_010400.5987325.p0 | Protein | 0.0 | 50 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | NC_010611.6233925.p0 | Protein | 0.0 | 50 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | NC_011595.7060572.p0 | Protein | 0.0 | 50 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | NC_008702.1.4609796. | Protein | 0.0 | 49 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | CP000034.1.gene3741. | Protein | 0.0 | 49 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | CP004022.1.gene2794. | Protein | 0.0 | 49 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | NC_002695.1.914942.p | Protein | 0.0 | 49 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | CP001918.1.gene250.p | Protein | 0.0 | 49 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | CP000647.1.gene4402. | Protein | 0.0 | 49 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | CP000675.2.gene392.p | Protein | 0.0 | 48 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | CP001138.1.gene4362. | Protein | 0.0 | 48 |
| rpoB | YP_001877648.1 | DNA-directed RNA polymerase subunit beta | NC_002516.2.881699.p | Protein | 0.0 | 46 |
