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Name : APP7_1008 (APP7_1008) Accession : YP_001968802.1 Strain : Actinobacillus pleuropneumoniae AP76 Genome accession: NC_010939 Putative virulence/resistance : Virulence Product : RTX-II toxin determinant A Function : - COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism COG ID : COG2931 EC number : - Position : 1123178 - 1126048 bp Length : 2871 bp Strand : - Note : - DNA sequence : ATGTCAAAAATCACTTTGTCATCATTAAAATCGTCCTTACAACAAGGATTGAAAAATGGGAAAAACAAGTTAAATCAAGC AGGTACAACACTGAAGAATGGTTTAACTCAAACTGGTCATTCTCTACAGAATGGGGCTAAAAAATTAATCTTATATATTC CTCAAGGCTATGATTCGGGTCAAGGAAATGGAGTTCAAGATTTAGTTAAAGCTGCTAATGATTTAGGTATTGAAGTATGG CGAGAAGAACGCAGCAATTTGGACATTGCAAAAACTAGCTTTGATACAACTCAGAAAATTTTAGGTTTTACTGATAGAGG AATTGTATTATTTGCACCTCAGCTAGATAATTTATTAAAGAAGAATCCTAAAATTGGCAATACATTAGGAAGTGCTTCTA GCATCTCACAAAATATAGGTAAAGCCAATACTGTATTAGGTGGTATTCAATCTATTTTAGGATCTGTTTTATCTGGAGTA AATCTGAATGAATTACTTCAAAATAAAGATCCTAATCAATTAGAACTTGCAAAAGCAGGGCTAGAACTGACTAATGAATT AGTTGGTAATATTGCTAGCTCGGTGCAAACTGTAGATGCATTTGCAGAACAAATATCTAAACTAGGTTCACATTTACAGA ATGTGAAAGGATTAGGAGGATTGAGTAATAAATTACAAAATCTACCAGATCTAGGAAAAGCAAGTTTAGGTTTGGACATT ATCTCTGGTTTACTTTCTGGAGCATCTGCAGGTCTCATTTTAGCAGATAAAGAGGCTTCAACAGAAAAGAAAGCTGCCGC AGGTGTAGAATTTGCTAACCAAATTATAGGTAATGTAACAAAAGCGGTCTCATCTTACATTCTTGCCCAACGAGTCGCTT CAGGTTTGTCTTCAACTGGTCCTGTCGCTGCATTAATCGCATCTACAGTTGCACTAGCTGTTAGCCCTCTTTCATTCTTA AATGTAGCTGATAAGTTTAAACAAGCTGATTTAATCAAATCATATTCTGAACGCTTCCAAAAATTAGGATATGATGGAGA TCGTTTATTAGCTGATTTTCACCGTGAGACAGGAACTATTGATGCTTCTGTAACAACAATTAACACTGCTTTAGCAGCTA TCTCCGGTGGAGTTGGAGCTGCAAGCGCGGGTTCTCTAGTCGGAGCTCCAGTTGCGTTACTCGTTGCTGGTGTTACGGGA CTTATTACAACTATTCTAGAATATTCTAAACAAGCCATGTTTGAACATGTTGCAAATAAGGTTCATGACAGAATAGTTGA ATGGGAGAAAAAACATAATAAAAACTATTTTGAGCAAGGTTATGATTCTCGTCATTTAGCTGATTTACAAGACAATATGA AGTTTCTTATCAATTTAAATAAAGAACTTCAGGCTGAACGCGTAGTAGCTATTACCCAACAAAGATGGGATAACCAAATT GGAGACCTAGCGGCAATTAGCCGTAGAACGGATAAAATTTCCAGTGGAAAAGCTTATGTGGATGCTTTTGAGGAGGGGCA ACACCAGTCCTACGATTCATCCGTACAGCTAGATAACAAAAACGGTATTATTAATATTAGTAATACAAATAGAAAGACAC AAAGTGTTTTATTCAGAACTCCATTACTAACTCCAGGTGAAGAGAATCGGGAACGTATTCAGGAAGGTAAAAATTCTTAT ATTACAAAATTACATATACAAAGAGTTGACAGTTGGACTGTAACAGATGGTGATGCTAGCTCAAGCGTAGATTTCACTAA TGTAGTACAACGAATCGCTGTGAAATTTGATGATGCAGGTAACATTATCGAATCTAAAGATACTAAAATTATCGCAAATT TAGGTGCTGGTAACGATAATGTATTTGTTGGGTCAAGTACTACCGTTATTGATGGCGGGGACGGACATGATCGAGTTCAC TACAGTAGAGGAGAATATGGCGCATTAGTTATTGATGCTACAGCCGAGACAGAAAAAGGCTCATATTCAGTAAAACGCTA TGTCGGAGACAGTAAAGCATTACATGAAACAATTGCCACCCACCAAACAAATGTTGGTAATCGTGAAGAAAAAATTGAAT ATCGTCGTGAAGATGATCGTTTTCATACTGGTTATACTGTGACGGACTCACTCAAATCAGTTGAAGAGATCATTGGTTCA CAATTTAATGATATTTTCAAAGGAAGCCAATTTGATGATGTGTTCCATGGTGGTAATGGTGTAGACACTATTGATGGTAA CGATGGTGACGATCATTTATTTGGTGGCGCAGGCGATGATGTTATCGATGGAGGAAACGGTAACAATTTCCTTGTTGGAG GAACCGGTAATGATATTATCTCGGGAGGTAAAGATAATGATATTTATGTCCATAAAACAGGCGATGGAAATGATTCTATT ACAGACTCTGGCGGACAAGATAAACTGGCATTTTCGGATGTAAATCTTAAAGACCTCACCTTTAAGAAAGTAGATTCTTC TCTCGAAATCATTAATCAAAAAGGAGAAAAAGTTCGTATTGGGAATTGGTTCTTAGAAGATGATTTGGCTAGTACAGTTG CTAACTATAAAGCTACGAATGACCGAAAAATTGAGGAAATTATTGGTAAAGGAGGAGAACGTATTACATCAGAACAAGTT GATAAACTGATTAAGGAGGGTAACAATCAAATCTCTGCAGAAGCATTATCCAAAGTTGTGAATGATTACAATACGAGTAA AGATAGACAGAACGTATCTAATAGCTTAGCAAAATTGATTTCTTCAGTCGGGAGCTTTACGTCTTCCTCAGACTTTAGGA ATAATTTAGGAACATATGTTCCTTCATCAATAGATGTCTCGAATAATATTCAATTAGCTAGAGCCGCTTAA Protein sequence : MSKITLSSLKSSLQQGLKNGKNKLNQAGTTLKNGLTQTGHSLQNGAKKLILYIPQGYDSGQGNGVQDLVKAANDLGIEVW REERSNLDIAKTSFDTTQKILGFTDRGIVLFAPQLDNLLKKNPKIGNTLGSASSISQNIGKANTVLGGIQSILGSVLSGV NLNELLQNKDPNQLELAKAGLELTNELVGNIASSVQTVDAFAEQISKLGSHLQNVKGLGGLSNKLQNLPDLGKASLGLDI ISGLLSGASAGLILADKEASTEKKAAAGVEFANQIIGNVTKAVSSYILAQRVASGLSSTGPVAALIASTVALAVSPLSFL NVADKFKQADLIKSYSERFQKLGYDGDRLLADFHRETGTIDASVTTINTALAAISGGVGAASAGSLVGAPVALLVAGVTG LITTILEYSKQAMFEHVANKVHDRIVEWEKKHNKNYFEQGYDSRHLADLQDNMKFLINLNKELQAERVVAITQQRWDNQI GDLAAISRRTDKISSGKAYVDAFEEGQHQSYDSSVQLDNKNGIINISNTNRKTQSVLFRTPLLTPGEENRERIQEGKNSY ITKLHIQRVDSWTVTDGDASSSVDFTNVVQRIAVKFDDAGNIIESKDTKIIANLGAGNDNVFVGSSTTVIDGGDGHDRVH YSRGEYGALVIDATAETEKGSYSVKRYVGDSKALHETIATHQTNVGNREEKIEYRREDDRFHTGYTVTDSLKSVEEIIGS QFNDIFKGSQFDDVFHGGNGVDTIDGNDGDDHLFGGAGDDVIDGGNGNNFLVGGTGNDIISGGKDNDIYVHKTGDGNDSI TDSGGQDKLAFSDVNLKDLTFKKVDSSLEIINQKGEKVRIGNWFLEDDLASTVANYKATNDRKIEEIIGKGGERITSEQV DKLIKEGNNQISAEALSKVVNDYNTSKDRQNVSNSLAKLISSVGSFTSSSDFRNNLGTYVPSSIDVSNNIQLARAA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hlyA | NP_755445.1 | hemolysin A | Virulence | PAI I CFT073 | Protein | 2e-149 | 49 |
| hlyA | CAD33759.1 | hemolysin A | Virulence | PAI I 536 | Protein | 1e-146 | 49 |
| hlyA | CAD42039.1 | HlyA protein | Virulence | PAI II 536 | Protein | 5e-148 | 48 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| APP7_1008 | YP_001968802.1 | RTX-II toxin determinant A | VFG0906 | Protein | 8e-150 | 49 |
| APP7_1008 | YP_001968802.1 | RTX-II toxin determinant A | VFG1500 | Protein | 6e-147 | 49 |
| APP7_1008 | YP_001968802.1 | RTX-II toxin determinant A | VFG1558 | Protein | 3e-148 | 48 |
| APP7_1008 | YP_001968802.1 | RTX-II toxin determinant A | VFG0840 | Protein | 5e-146 | 45 |
