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Name : iscS (RAF_ORF0676) Accession : YP_002845311.1 Strain : Rickettsia africae ESF-5 Genome accession: NC_012633 Putative virulence/resistance : Unknown Product : cysteine desulfurase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG1104 EC number : 4.4.1.- Position : 707564 - 708796 bp Length : 1233 bp Strand : + Note : catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis DNA sequence : ATGAACCCACAATTAAACAATTTAACCTTACCGATATATATGGATTATCAGGCGACGACTCCAATAGATCCAAGAGTAAT GGAGGCAATGTTGCCTTATTTTACTACCAAGTTCGGCAATCCTCATTCACGCAGCCATTCTTTCGGTTGGGAGGCAGAAA ACGCCGTTGAAGAAGCAAGGAGTATGGTAGCAAAGTTAATAGGAGCGGATACTAAAGAAATTATTTTCACTTCCGGTGCA ACTGAGTCTAACAATCTTGCAATAAAGGGAATAGCAAAATTTTACAGCAATAAAAAGAATCATATTATTACCGTAGTCAG TGAACATAAATGCGTACTTGATGCTTGCAGGCATTTAGAGCAAGAAGGTATAAAAATCACATACTTACCGATTAAGCCAA ATGGAATAATCGATTTAGAAACTCTAAAAAATGCCATTACCGATCAGACTATGTTAGTTTCAGTTATGGTGGTTAATAAT GAAATAGGTGTTGTTCAGCCTTTAAAGGAAATCGGGCAAATTTGCCGTGAAAAGGGCGTTTTTTTTCATTCCGATATTGC TCAAGGTTTTGGTAAAATTCCAATTGATGTTAACGCATTTAATATTGATCTTGCCAGTATCTCAGGGCATAAAATTTACG GTCCGAAAGGAATAGGTGCATTATATGTAAGGAAAAAACCTCGTGTGCGTGTTACACCGCTCATAAACGGTGGCGGACAG GAGAGAGGTATACGTTCAGGTACGCTACCGACTCCTTTAATCGTAGGGCTTGGCATGGCTGCTGAAATAGCGTATAGTGA GATGGAAAAAGATACTAAGCACATAAATTACTTATTCGACAGATTTTTAAATAATATACATAAGCGAATTTCAAAAGTTT ATTTAAACGGCGATAAAAATCAAAGATATAAAGGTAATTTAAATTTAAGCTTTGCCGGAGTTGAAGGAGAATCAATGATC CTTGCCATTAAAGATTTAGCGGTTTCCTCCGGTTCTGCTTGTACTTCTGCCTCTTTAGAACCGTCATATGTTTTACGTTC TATGGGAATCGGTGAAGAGCTTGCCCATACTGCAATTAGGTTCGGCATAGGTAGATTTACTACCGAGCAGGAAGTTGACT ACGCAGTAAATTTAATATGCTCAAAAATCGATAAACTAAGGGAATTAAGCCCTCTTTGGGAAATGATGCAAGAGGGAATT GATTTGAAAAAGATTAAATGGGCTGTACATTGA Protein sequence : MNPQLNNLTLPIYMDYQATTPIDPRVMEAMLPYFTTKFGNPHSRSHSFGWEAENAVEEARSMVAKLIGADTKEIIFTSGA TESNNLAIKGIAKFYSNKKNHIITVVSEHKCVLDACRHLEQEGIKITYLPIKPNGIIDLETLKNAITDQTMLVSVMVVNN EIGVVQPLKEIGQICREKGVFFHSDIAQGFGKIPIDVNAFNIDLASISGHKIYGPKGIGALYVRKKPRVRVTPLINGGGQ ERGIRSGTLPTPLIVGLGMAAEIAYSEMEKDTKHINYLFDRFLNNIHKRISKVYLNGDKNQRYKGNLNLSFAGVEGESMI LAIKDLAVSSGSACTSASLEPSYVLRSMGIGEELAHTAIRFGIGRFTTEQEVDYAVNLICSKIDKLRELSPLWEMMQEGI DLKKIKWAVH |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | AAT96060.1 | cysteine desulfurase | Not tested | T-PAI | Protein | 2e-110 | 57 |
