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Name : lysS (Kole_2033) Accession : YP_002941715.1 Strain : Kosmotoga olearia TBF 19.5.1 Genome accession: NC_012785 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : - Position : 2159459 - 2160973 bp Length : 1515 bp Strand : + Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGAACGAACAAATAAGACAACATAAACTCAATGAGATAGAGGAACTTCGTTCCATGGGGATAGAACCGTATCCTCATCA TTTCGAAAAGACCCATAGTACCAGTGATATCCGCAAAGAATATGATATGCTTCAGCCATCGGAAACCAAAGAAGATACAA CCATTTCAGTTGCAGGAAGAGTGATGGCTCTCAGGCATCATGGTAAATCATCGTTCTTTGTCTTGAAGGATAGCGATGGA AGAATACAAGCATATATCAGAAAAGATTCCGTTGGCGACGAAGCATTCAAACTTTTCAAGAAATATGTCAGTATCGGAGA TTTTGTTGGTGTAAAAGGGTTCCCGTTTAAAACCCACACAGGTGAACTGTCTATTTTTGTTAAGGATTTCAAGCTCCTGT CCAAAGCTATAAGAACGATGCCTGAAAAATGGCATGGAATAAAGGACAAGGAAATAATTTATAGGCAGAGATACGTGGAA ATGATTGCCAGCGATGACGCCATTAAAAGATTCAAGATCAGATTCGAGCTCCTAAGACGTGTTAGAGAGTTTCTTAATGC AAGGGGTTTTATAGAAGTAGAAACGCCGATCCTTCATTCTGTCACCGGTGGAGCTTCCGCAAGACCATTTGTGACCCATA TCAACGTTTTTGATTCGGATATGTACCTGAGAATCGCTGAGGAGCTATATCTCAAAAGATATCTAGTGGGCGGATTTGAG AAGATATATGAAATTGGAAAGAATTTCAGGAACGAGGGAATGTCTTATAAGCATCATCCGGAGTTTGTCATGATGGAACT ATATCAGGCTTATGCCGACTACAACGATATTATGGACCTTACCGAGGATCTTATAAGCACCGTCGTAGAGCAGCTCACAG GTTCCACGAAGATCGTTTATCAGGGTAAGGAAATAGATTTTGCCAAACCATGGCTGCGTATCAAGATGGCTGATTTCATC AAAGAAAAGCTCGGAGTTGATATACTTGAAGATTCCGATGAAAGGTTAATTGAGGTTCTTGAGAAACATAACAGTGTTCC TGAGATCAAAGAAAGAGGCCATCTCATAGAAAAGTTATGGGATCTTGTTGAGGATGATATTGTACAACCTACCTTTGTTG TTGAACATCCTGTCATCATTTCTCCACTTGCGAAGGTCCACAGAGAAGATCCGAGGGTAACAGAAAGGTTTGAATTAATT ATAAATGGCATGGAATGTGCGAACGCCTTTAGTGAACTCAATGACCCAATCGAACAGTACAGGAGATTCCTCCATCAGGC TGGATTAAGAGAAGCCGGTGATGCCGAAGCACAAATGATGGATCGTGATTTCATACGCGCTTTGGAATATGGCATGCCCC CAACTGGAGGTCTTGGGATTGGTTGGGACAGGATTCTCATGTTCGTTACCGATTCTCCCACCATACGCGATGTGATTCCC TTCCCGCTGGTAAGGCCGTTGAGTTTTGAAGAAGAGGAGAAAATTGTTACCGATGCAGAGGAAGAGGAAAGCTGA Protein sequence : MNEQIRQHKLNEIEELRSMGIEPYPHHFEKTHSTSDIRKEYDMLQPSETKEDTTISVAGRVMALRHHGKSSFFVLKDSDG RIQAYIRKDSVGDEAFKLFKKYVSIGDFVGVKGFPFKTHTGELSIFVKDFKLLSKAIRTMPEKWHGIKDKEIIYRQRYVE MIASDDAIKRFKIRFELLRRVREFLNARGFIEVETPILHSVTGGASARPFVTHINVFDSDMYLRIAEELYLKRYLVGGFE KIYEIGKNFRNEGMSYKHHPEFVMMELYQAYADYNDIMDLTEDLISTVVEQLTGSTKIVYQGKEIDFAKPWLRIKMADFI KEKLGVDILEDSDERLIEVLEKHNSVPEIKERGHLIEKLWDLVEDDIVQPTFVVEHPVIISPLAKVHREDPRVTERFELI INGMECANAFSELNDPIEQYRRFLHQAGLREAGDAEAQMMDRDFIRALEYGMPPTGGLGIGWDRILMFVTDSPTIRDVIP FPLVRPLSFEEEEKIVTDAEEEES |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 1e-92 | 45 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | YP_002941715.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 8e-93 | 45 |
