Gene Information

Name : rpoB (Coch_0426)
Accession : YP_003140550.1
Strain : Capnocytophaga ochracea DSM 7271
Genome accession: NC_013162
Putative virulence/resistance : Unknown
Product : DNA-directed RNA polymerase subunit beta
Function : -
COG functional category : K : Transcription
COG ID : COG0085
EC number : -
Position : 535179 - 538988 bp
Length : 3810 bp
Strand : +
Note : DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme

DNA sequence : 
ATGCTTACGAATCAAACCGCAAGAGTGAATTTTGCTTCCGTGAAACACGTTCCTGAATACCCTGACTTCTTGGATATTCA
AATCAAATCGTTTCAAGAGTTCTTTCAGATGGAGACCAAATCGGAAGACCGAGTGCACGAGGGATTGTATCATACCTTTA
AAGAGAACTTTCCTATATCGGACACTCGCAACCAATTCGTATTGGAGTTTCTCGACTATTTCGTAGACCCTCCTCGCTAC
ACTATCCAAGAATGTATAGAACGCGGTCTTACTTATAGTGTGCCTCTGAAAGCCCGATTAAAGCTTTATTGTACTGACCC
CGAGCACGAAGATTTTGAAACTATCGTACAAGACGTTTATTTGGGCACAATCCCTTATATGACAGCAAGCGGAACATTCG
TTATCAACGGAGCTGAGCGTGTAGTAGTATCGCAGTTACACCGTTCACCAGGGGTATTCTTCGGTCAGTCGTTTCACGCT
AATGGTACTAAACTCTACTCTGCACGTATTATTCCTTTCAAAGGTTCGTGGATTGAGTTTGCTACCGATATCAACAACGT
GATGTATGCCTATATCGACCGTAAGAAAAAACTCCCTGTTACAACACTCTTCCGTGCGATTGGGTTTGAACGTGATAAAG
ATATATTGGAAATATTCGACCTTGCAGAAGAAATAAAGGTTTCTAAAACAGGACTTAAAAAATACATCGGTCGTCGTTTG
GCTGCCCGTGTGCTCAACACTTGGCACGAAGACTTCGTAGACGAAGATACCGGAGAGGTAGTATCTATCGAGCGTAATGA
GATTATCCTCGACCGCGATACTGTACTCGACGAAGATAACATTCAAGAAATCTTAGAAGCTGATGTAAAGACCATTCTTC
TTCACAAAGAAGATAGTCAGGCTACCGACTATACCATTATCCACAATACTTTACAAAAAGACCCTACCAACTCTGAGAAG
GAAGCAGTGGAACACATTTACCGACAGTTGCGTAATGCTGAACCGCCCGATGAGGAAACTGCTCGCGGTATTATCGACAA
GTTGTTCTTCTCAGACCAACGTTACAATTTGGGAGACGTAGGGCGTTACCGTATCAACAAAAAATTGGGATTGGATACCC
CTATGGAAAAGCAAGTGCTTACCAAAGAGGATATCATTACCATTGTAAAATATTTGATTGAGCTCATCAACTCTAAAGCA
GAGGTAGATGATATCGACCACTTGTCTAACCGCCGTGTGCGCACAGTAGGAGAGCAATTGGCAGCTCAGTTTGGCGTAGG
TCTTTCTCGTATGTCGCGCACTATCCGTGAACGTATGAACGTACGTGACAACGAGGTATTTACTCCTATCGATTTGATCA
ATGCGAAGACCCTTTCTTCTGTAATTAACTCGTTCTTTGGTACAAACCAATTATCTCAGTTTATGGATCAAACGAATCCT
TTGGCTGAGATTACTCACAAACGCCGTTTGTCCGCCTTAGGGCCTGGAGGTTTGTCGCGTGAGCGTGCGGGCTTTGAGGT
GCGAGACGTACACTATACTCACTACGGACGTTTGTGCCCTATTGAAACCCCAGAAGGGCCGAATATCGGTTTGATATCTT
CGTTGGCGGTATTCTCGAAGGTAAACGGTATGGGCTTTATAGAAACCCCTTATCACAAAGTTACTAATGGGAAGGTAGAT
CTTAAAGATATGACCTACCTCACTGCCGAAGACGAAGAAGGACTCAAAATTGGTATGGCTAATATCGCATTAGACGATAA
AGCTAATATCACTGAAGAAAAAGTGGTTGTAAAAGAAGATGGTGACTTCCCTGTAATTGAACCTAACGAAGTACAATATA
TAGACGTTGCTCCTAACCAAATCGCTTCTATTTCGGCTTCCCTTATTCCGTTCTTGGAACACGACGACGCGAACCGTGCG
TTAATGGGCTCGAATATGATGCGTCAGGCAGTACCTTTGTTAAGACCTGAAGCGCCTATCGTAGGAACAGGTTTGGAACG
CCGTGTAGCTTCAGATGCCCGTGTGCTTATGAACGCAGAGGGTGATGGTACTGTTGATTATGTAGATGCTGATAAAATCA
TTATCACTTATGACCGTACTGATGAACAAAAATTGGTAAGCTTTGATGCTGATGAAACAGTATATAACCTTATCAAATTC
CAAAAAACAAACCAAGGCACTTGTATCAACTTAAAACCGATAGTTGAAAAAGGTGAGAGAGTGAAAAAAGGTCAGGTGTT
GTGTGAAGGTTATGCTACTGAAAACGGAGAGTTAGCACTCGGTCGTAATATGAAGGTAGCGTTTATGCCTTGGAAAGGTT
ATAACTTTGAGGACGCGATTGTGATTTCGGAACGCGCTGTACGCGAGGATTTATTCACTTCTATCCACATTGATGAATAC
GCTTTGGAAGTACGTGATACTAAATTGGGAGCTGAAGAGCTTACTAATGATATCCCGAACGTATCGGAAGATGCGACCAA
AGATTTGGACGAATACGGTATGATTCGCATTGGAGCAGAAGTACGCCCAGGTGATATTCTTATCGGTAAGATTACTCCTA
AAGGAGAATCAGACCCTACCCCTGAAGAGAAACTCCTCCGTGCTATCTTTGGTGATAAAGCAGGTGATGTGAAAGACGCT
TCTCTAAAAGCTTCACCTTCACTTTACGGGGTGGTTATCGACAAGAAATTGTTTTCACGTGCAGTAAAAGACAAACGCAA
ACGCAGTAAAGATAAAGAAGATGTAGCACAATTAGAAGCTAATTACAACGCTAAGTTTGAAACTCTTCGCTCTAAATTAT
TGGAAAAACTATATAGTTTGGTGGCTGAAAAGACTTCGGAAGGAGTAGTAAACGACCTCGGTGAAGAAATTGTGCCTAAA
GGTAAGAAATATACTAAGAAAGTGCTTGAAGGTATTGAGGATTATGCTCACCTTACTTCTGCAGGTTGGACTGACGATAA
GCACATCAACGGTCTTATAGATGACCTTTTGCACAACTATCGCATTCGTGAAAATGACCTACAAGGAGGATTACGTCGCG
ATAAATTTACCATTGCTGTGGGTGACGAATTACCTGCAGGTATTCTAAAATTAGCTAAAATTTACGTGGCTAAGAAACGT
AAGCTAAAAGTAGGGGATAAGATGGCAGGTCGACACGGTAACAAGGGTATCGTAGCACGTATCGTTCGCGATGAGGATAT
GCCATTCCTTGAAGACGGAACTCCGGTAGACATCGTGTTGAACCCTCTTGGGGTACCTTCACGTATGAACATCGGTCAGA
TATACGAAACTGTATTGGGTTGGGCAGGACAAAAGCTCGGCAAGAAGTTTGCAACTCCTATCTTCGATGGAGCATCGCTT
GAGCAAATTAATGAGCTTACCGATGAAGCAGGCGTACCGCGTTTCGGTCATACTTATCTATACGATGGTGGTACCGGTGA
ACGTTTTGACCAAAAAGCCACTGTAGGGGTGATTTATATGATCAAACTCGGACATATGATTGACGATAAGATGCACGCTC
GTTCTATCGGTCCGTACTCACTTATCACCCAACAGCCATTGGGAGGTAAAGCCCAATTTGGTGGACAGCGTTTTGGAGAG
ATGGAGGTATGGGCATTGGAGGCTTATGGAGCATCTAGTACCTTACGCGAAATCTTAACTGTAAAATCTGACGACGTAGT
AGGTCGTGCCAAAACTTACGAAGCGATTGTAAAAGGTGAGACAATGCCAGAACCAGGATTGCCAGAATCTTTCAACGTAT
TGATGCACGAGCTCAAAGGTCTTGGATTGGATATCAGACTTGAAGAATAA

Protein sequence : 
MLTNQTARVNFASVKHVPEYPDFLDIQIKSFQEFFQMETKSEDRVHEGLYHTFKENFPISDTRNQFVLEFLDYFVDPPRY
TIQECIERGLTYSVPLKARLKLYCTDPEHEDFETIVQDVYLGTIPYMTASGTFVINGAERVVVSQLHRSPGVFFGQSFHA
NGTKLYSARIIPFKGSWIEFATDINNVMYAYIDRKKKLPVTTLFRAIGFERDKDILEIFDLAEEIKVSKTGLKKYIGRRL
AARVLNTWHEDFVDEDTGEVVSIERNEIILDRDTVLDEDNIQEILEADVKTILLHKEDSQATDYTIIHNTLQKDPTNSEK
EAVEHIYRQLRNAEPPDEETARGIIDKLFFSDQRYNLGDVGRYRINKKLGLDTPMEKQVLTKEDIITIVKYLIELINSKA
EVDDIDHLSNRRVRTVGEQLAAQFGVGLSRMSRTIRERMNVRDNEVFTPIDLINAKTLSSVINSFFGTNQLSQFMDQTNP
LAEITHKRRLSALGPGGLSRERAGFEVRDVHYTHYGRLCPIETPEGPNIGLISSLAVFSKVNGMGFIETPYHKVTNGKVD
LKDMTYLTAEDEEGLKIGMANIALDDKANITEEKVVVKEDGDFPVIEPNEVQYIDVAPNQIASISASLIPFLEHDDANRA
LMGSNMMRQAVPLLRPEAPIVGTGLERRVASDARVLMNAEGDGTVDYVDADKIIITYDRTDEQKLVSFDADETVYNLIKF
QKTNQGTCINLKPIVEKGERVKKGQVLCEGYATENGELALGRNMKVAFMPWKGYNFEDAIVISERAVREDLFTSIHIDEY
ALEVRDTKLGAEELTNDIPNVSEDATKDLDEYGMIRIGAEVRPGDILIGKITPKGESDPTPEEKLLRAIFGDKAGDVKDA
SLKASPSLYGVVIDKKLFSRAVKDKRKRSKDKEDVAQLEANYNAKFETLRSKLLEKLYSLVAEKTSEGVVNDLGEEIVPK
GKKYTKKVLEGIEDYAHLTSAGWTDDKHINGLIDDLLHNYRIRENDLQGGLRRDKFTIAVGDELPAGILKLAKIYVAKKR
KLKVGDKMAGRHGNKGIVARIVRDEDMPFLEDGTPVDIVLNPLGVPSRMNIGQIYETVLGWAGQKLGKKFATPIFDGASL
EQINELTDEAGVPRFGHTYLYDGGTGERFDQKATVGVIYMIKLGHMIDDKMHARSIGPYSLITQQPLGGKAQFGGQRFGE
MEVWALEAYGASSTLREILTVKSDDVVGRAKTYEAIVKGETMPEPGLPESFNVLMHELKGLGLDIRLEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00346 YP_008207811.1 DNA-directed RNA polymerase, beta subunit/140 kD subunit Not tested AbaR25 Protein 0.0 46
BJAB0868_00350 YP_008211676.1 DNA-directed RNA polymerase, beta subunit/140 kD subunit Not tested AbaR26 Protein 0.0 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_009085.4918494.p0 Protein 0.0 46
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_010400.5987325.p0 Protein 0.0 46
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_010611.6233925.p0 Protein 0.0 46
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_011595.7060572.p0 Protein 0.0 46
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_010410.6003841.p0 Protein 0.0 46
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_011586.7046027.p0 Protein 0.0 46
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta CP000675.2.gene392.p Protein 0.0 46
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta CP002695.1.gene18.p0 Protein 0.0 46
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_002516.2.881699.p Protein 0.0 45
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_002695.1.914942.p Protein 0.0 45
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta CP001138.1.gene4362. Protein 0.0 45
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta CP000034.1.gene3741. Protein 0.0 45
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta CP001918.1.gene250.p Protein 0.0 45
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta CP004022.1.gene2794. Protein 0.0 45
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_008702.1.4609796. Protein 0.0 45
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta CP000647.1.gene4402. Protein 0.0 45
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_011035.1.6448762. Protein 0.0 44
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_009641.5330265.p0 Protein 4e-175 43
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_010079.5776819.p0 Protein 4e-175 43
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_002952.2860169.p0 Protein 5e-175 43
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_007622.3792928.p0 Protein 4e-175 43
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_002745.1123305.p0 Protein 4e-175 43
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_007795.3920377.p0 Protein 4e-175 43
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_009632.5315067.p0 Protein 4e-175 43
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_009782.5559150.p0 Protein 4e-175 43
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_002951.3236234.p0 Protein 7e-175 43
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_002953.2862188.p0 Protein 4e-175 43
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_013450.8613267.p0 Protein 4e-175 43
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_007793.3914836.p0 Protein 4e-175 43
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_003923.1002608.p0 Protein 4e-175 43
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_002758.1120515.p0 Protein 4e-174 42
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_009487.5169226.p0 Protein 6e-174 42
rpoB YP_003140550.1 DNA-directed RNA polymerase subunit beta NC_012469.1.7686402. Protein 2e-168 42