Gene Information

Name : Aaci_2352 (Aaci_2352)
Accession : YP_003185748.1
Strain : Alicyclobacillus acidocaldarius DSM 446
Genome accession: NC_013205
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 2416685 - 2418103 bp
Length : 1419 bp
Strand : -
Note : KEGG: vco:VC0395_A0037 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence : 
ATGCGAAAGACGAAGATTGTGGCCACCATCGGGCCTGCGAGCGAATCGCTCGACATGTTGACCAAGCTGATTGAGGCCGG
TTTGGATGTCGCCCGACTCAACTTCTCCCACGGTACATACGAAGAACACGCGGAGCGCATCCGGCGCATTCGCGAGGCGT
CGGCCCGCGTGGGCAAGCACGTCGGCATCATGCTTGACATCAAGGGACCGAAAATTCGAACGGGCAAGATCCAAGGCGGC
CAGGTGGAGCTGAAGGACGGGGACGAGATCGTCCTCACCATTGATCCGGTGGAGTACGGCACGAAGGAGCGCGTGTGGGT
CTCCTACGAAGGGCTCGTGGAAGACGTGTATCCCGGCGCGCCAATTCGCATCGACGACGGGCTCATTGGACTCGAGGTCA
TCCAGGTCAAGGGCCACGACATTTACTGCCGCGTCACCAACGGCGGCGTGCTGAAGGACAACAAGGGCATCAACGTCCCG
GGCGTGACGCTCAGGATTCCGGGCGTCACCGAGAAGGACAAGGCGGACATCCGCTTCGGCATTGAGCACGGCGTCGACAT
GATCGCGGCGTCGTTCGTGCGCAAGGCGGCGGACGTGCTCGAGGTGCGCCGAATTCTGGAGGAGCACAATTATCAGGCGG
ACATCATCTCGAAGATCGAGACGCGCGAGGGGCTGGATCGGCTCGACGAGATCGCGCAGGTGTCGGACGGCATGATGGTG
GCCCGCGGCGATCTCGGCGTGGAGATCCCGACGGAAGAGGTGCCGCTCGCGCAGAAGCGGATTATCTCCATCTGCAACCG
GTACGGCAAGCCGGTCATCACGGCGACGCAGATGCTCGATTCGATGCAGCGCAATCCGCGGCCCACGCGCGCCGAGGCGA
GCGACGTGGCGAACGCCATCTTCGACGGCACGGACGCCATCATGCTCTCGGGCGAAACAGCGGCGGGGCGGTATCCGCTG
GAATCCGTGCGGACGATGGCGCAGATCGCGGAGCGGGCCGAGGCCGCCATCGCGCACGACGAGGTGGCGTACCGGCACCG
CACGGAGGTCACGCACACCGTGTCCGACTCGCTCGCGCACGCCGTGCGCACGCTCGCGGCCGATCTCGACGTGATCTCCA
TCATCACGGCGACGACGTCCGGGCACACCGCCCGCTGTGTGTCCAAGCACCGGCCCATGACGCCCATCATCGCGGTCACG
CCGTTCGATCACGTCGCGCGGCGCCTGACGCTCTACTGGGGCGTCCTTCCCGTCGTCGTCCCGGACATCGCGGGCACGAC
GGACGAGTTGCTCGCGAGTTCCGTTCAAGGGGCGCTCTCGACTGGCTATGTGCACAAGGGCGATCGCGTCATCATCATGG
GCGGCATTCCCGCGGGCACGGCGGGCACGACGAACTTCATGAAGGTGCACACGGTCTGA

Protein sequence : 
MRKTKIVATIGPASESLDMLTKLIEAGLDVARLNFSHGTYEEHAERIRRIREASARVGKHVGIMLDIKGPKIRTGKIQGG
QVELKDGDEIVLTIDPVEYGTKERVWVSYEGLVEDVYPGAPIRIDDGLIGLEVIQVKGHDIYCRVTNGGVLKDNKGINVP
GVTLRIPGVTEKDKADIRFGIEHGVDMIAASFVRKAADVLEVRRILEEHNYQADIISKIETREGLDRLDEIAQVSDGMMV
ARGDLGVEIPTEEVPLAQKRIISICNRYGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGRYPL
ESVRTMAQIAERAEAAIAHDEVAYRHRTEVTHTVSDSLAHAVRTLAADLDVISIITATTSGHTARCVSKHRPMTPIIAVT
PFDHVARRLTLYWGVLPVVVPDIAGTTDELLASSVQGALSTGYVHKGDRVIIMGGIPAGTAGTTNFMKVHTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-90 48
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-90 48
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-90 48
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-90 48
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 5e-59 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Aaci_2352 YP_003185748.1 pyruvate kinase VFG0479 Protein 7e-91 48