Gene Information

Name : Astex_0604 (Astex_0604)
Accession : YP_004086443.1
Strain :
Genome accession: NC_014816
Putative virulence/resistance : Virulence
Product : ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 640512 - 641900 bp
Length : 1389 bp
Strand : -
Note : TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; KEGG: ccs:CCNA_03135 flagellum-specific ATP synthase FliL; SMART: AAA ATPase

DNA sequence : 
TTGAAAACCGGCAATCCGTTAACCTTTCTTAAGGCCCCGTTCACCATAATCGTGGCCATGCAGGACCTTCTCCATACCGC
TCGCAATATCGACCCGATGCAGGTCTATGGCCGTGTGGCTGTGGTCAATGGCTTGCTGATCGAAGCCAAGGGCGGCATGT
CGTTCATGGAGGTCGGCTCGCGCTGCGAGATCATGCGCCGGCACGACACCCCCCTGCCCGTCGAAGTCGTCGGCTTCCGC
GAAGACCGCGCCCTGATGATGCCCTTCGGCCCGGTCGAAGGCGTGGCGCCCGGTGCAGAAATCCGCATCTCCAACGAAGG
GGCGAAGGTCTATCCTTCGACCGCCTGGCTGGGGCGGATTATTGATGCCTTTGGTGATCCCATCGACGGGCTGGGCCCCC
TGCCCAAGGGCGGCATTGGTTATCCGCTGAAAGCCGCACCGCCGCCTGCCCATTCGCGGGCGCGGGTGGGGGAGCGCCTT
GACCTCGGTGTGCGGGCGATGAACGTCTTTACCACCTGCTGCCGCGGGCAGCGTCTGGGGGTGTTCGCCGGTTCCGGCGT
CGGCAAGTCGGTGCTTTTGTCCATGCTGGCGCGCGAAGCGGCCTGTGACGCGGTCGTGGTCGGGCTGATCGGCGAACGCG
GCCGCGAAGTGCGTGAATTTGTCGAAGAGACGTTGGGCGAAGCTGGCATTTCCCGCGCCATCGTCGTCGTCGCCACCTCC
GATGAGCCCGCGCTGAAACGCCGTCAGGCCGCCTATATGACGCTGGCCCTGTCAGAGTTTCTGCGCGATCAGGGGCTTGA
GGTCCTGTGTCTGATGGACTCTGTAACGCGCTTTGCCATGGCCCAGCGCGAGATCGGTCTGGCCACCGGAGAGCCGCCGA
CGACCAAGGGCTATACCCCTACCTGCTTCGCCGAATTGCCCAAGCTGCTGGAGCGCGCTGGCCCCGGCCCGCTGCTGCCC
GACGGGACGCAAACCGGCCCCATCACCGGGCTGTTCACCGTTCTGGTCGATGGCGATGACCACAATGAGCCGATTGCCGA
TGCCGTGCGCGGTATCCTTGACGGCCACATCGTTATGAGCCGTTCGATTGCTGAGCGCGGCCGCTTCCCGGCCATCGACG
TGCTAAAAAGCATCAGCCGCACCATGCCAGGGTGCCAGACGCTCGCCGAACGTGAGGTGGTGCGCAATGCCCGTGCCGTC
ATGTCGGCCTATACGAACATGGAAGAACTGATCCGCATCGGGGCCTATCGCACAGGCGCCGATCCGCTGGTCGATCGGGC
GATTCAGCTCAACCCCAGCATCGAACAATTTCTGTCGCAAAGCCCCGATGAGGCCACAAGTCTTGACGACTCCTTTACCC
TTTTGGGCCAGATTCTCAGCTCTCAATAA

Protein sequence : 
MKTGNPLTFLKAPFTIIVAMQDLLHTARNIDPMQVYGRVAVVNGLLIEAKGGMSFMEVGSRCEIMRRHDTPLPVEVVGFR
EDRALMMPFGPVEGVAPGAEIRISNEGAKVYPSTAWLGRIIDAFGDPIDGLGPLPKGGIGYPLKAAPPPAHSRARVGERL
DLGVRAMNVFTTCCRGQRLGVFAGSGVGKSVLLSMLAREAACDAVVVGLIGERGREVREFVEETLGEAGISRAIVVVATS
DEPALKRRQAAYMTLALSEFLRDQGLEVLCLMDSVTRFAMAQREIGLATGEPPTTKGYTPTCFAELPKLLERAGPGPLLP
DGTQTGPITGLFTVLVDGDDHNEPIADAVRGILDGHIVMSRSIAERGRFPAIDVLKSISRTMPGCQTLAEREVVRNARAV
MSAYTNMEELIRIGAYRTGADPLVDRAIQLNPSIEQFLSQSPDEATSLDDSFTLLGQILSSQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-74 45
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-61 43
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-61 43
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 9e-62 43
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-62 43
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 7e-62 43
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-70 43
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-70 43
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-71 43
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-71 43
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-70 43
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-70 43
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-69 43
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-70 43
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-61 43
escN AAK26715.1 EscN Virulence LEE Protein 3e-61 43
escN AAL57542.1 EscN Virulence LEE Protein 3e-61 43
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-61 43
escN AAC38383.1 EscN Virulence LEE Protein 5e-61 43
escN AAC31513.1 L0034 Virulence LEE Protein 3e-61 43
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-61 43
escN YP_003236088.1 translocator EscN Virulence LEE Protein 6e-61 43
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-61 43
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-61 43
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 9e-70 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-63 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 8e-64 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-64 42
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 6e-68 42
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-59 42
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-60 42
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-60 42
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-61 42
escN YP_003223475.1 translocator EscN Virulence LEE Protein 3e-61 42
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-56 41
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 8e-59 41
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-60 41
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-60 41
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 5e-61 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Astex_0604 YP_004086443.1 ATPase VFG2499 Protein 6e-75 47
Astex_0604 YP_004086443.1 ATPase VFG2331 Protein 8e-72 46
Astex_0604 YP_004086443.1 ATPase VFG1254 Protein 5e-69 46
Astex_0604 YP_004086443.1 ATPase VFG2144 Protein 2e-74 45
Astex_0604 YP_004086443.1 ATPase VFG0048 Protein 7e-74 44
Astex_0604 YP_004086443.1 ATPase VFG0192 Protein 3e-73 44
Astex_0604 YP_004086443.1 ATPase VFG0515 Protein 4e-62 43
Astex_0604 YP_004086443.1 ATPase VFG0390 Protein 5e-73 43
Astex_0604 YP_004086443.1 ATPase VFG0812 Protein 2e-61 43
Astex_0604 YP_004086443.1 ATPase VFG0730 Protein 3e-61 43