Gene Information

Name : rpoB (SGRA_2310)
Accession : YP_005322623.1
Strain : Saprospira grandis Lewin
Genome accession: NC_016940
Putative virulence/resistance : Unknown
Product : DNA-directed RNA polymerase subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.6
Position : 2344125 - 2347955 bp
Length : 3831 bp
Strand : +
Note : COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit

DNA sequence : 
ATGGCAAAAAGTACAACTCTTACTCCCAAAAGACCAGAACGCTTTAGTTTCGGTAAAATCCAACACGATAACCACTATCC
GGATTTTCTCGAAATTCAAGTTAAGTCTTTTGAGGAGTTTTTTCAGTTAGAGACCACCCCTGAAAGTCGCTTCAATGAGG
GACTCTATCAGGTGTTCCAAGAAAATTTTCCAATCACTGATGCCCGCAACATCTTTGTCCTGGAATTCCTTAACTATTTT
ATCGACCCTCCTCGCTATACTATCGATGAATGTATGGAGAGAGGGCTTACCTATAGCGTCCCACTCAAAGCAAAACTTCG
CCTGTCTTGTAATGATGAAGAGCATGTCGACTTTGAGCAAACTGTACAAGATGTATTCTTAGGCAATATCCCTTATATGA
CGCCTAAAGGTACATTCGTAATCAATGGCGCCGAACGTGTAATCGTTTCTCAACTGCACCGCTCTCCCGGTGTATTTTTT
GGCCAAAGCCGCCACCCTAACGGTACCAAAATCTACTCTGCCCGTGTTATCCCTTTCAAAGGAGCTTGGATGGAGTTTGC
TACCGATATTAACTCGGTGATGTATGCCTACATCGACCGCAAAAAGAAGTTTCCCGTTACTACGCTCCTCCGTGCCATCG
GATACGACGGAGACCGCGATATCCTTGGCCTATTCGGCCTCGCCGATGAAGTGGAAGCTACGCAGGAAGCCCTTGAACAA
CACCTAGGCCGTAAACTCGCCGCCCGCGTTCTCCGCTCTTGGGTAGAGGACTTTGTCGATGAGGATACCGGTGAGGTGGT
GTCTATCGAACGTAATGAGGTGATCCTCGAACGTGACGTAATCCTTGATGAAGATAATATTCAAGAGGTGATCGATATCG
GAGTAGATAAGGTGATCCTCCAAAGAGAAAATGTAGAAGATGATTATAGCATTATCTACAATACACTCCAAAAGGATACT
TCTAACTCTGAAATCGAAGCCGTTCAACATATCTATCGCCAATTGCGTGGATCTGATCCACCCGATGACGAAACCGCTCG
CGGTATTATCGATAAACTCTTCTTCTCCGATAAGCGCTATAGCCTCGGTGAAGTCGGCCGATATAAAATTAACCGCAAAC
TAGAACTCGACGAAAGTAACGATACTTCTGTCCTTACTAAAGAGGATATTATCGCTATCGTTAAGTATCTAGTCAAATTG
ATTAACCAAAAAGCTGAGATCGATGATATCGACCACCTCAGCAACCGCCGTGTCCGTACCGTTGGCGAACAACTCTATGC
CCAGTTTGGCGTAGGCCTAGCCCGTATGGCCCGCACGATCCGCGAAAGAATGAATGTTCGCGATAATGAAGTGTTTACTC
CCGTAGACCTCATCAACGCAAGAACACTCTCTTCTGTGATCAACTCTTTCTTTGGTACTAGCCAACTTTCTCAGTTCCTC
GACCAAACTAACCCGCTCTCAGAAATTACACACAAACGTAGAATTTCTGCTCTCGGTCCAGGTGGTCTCTCTAGAGAAAG
AGCAGGCTTTGAGGTGCGTGACGTTCACTATTCTCACTATGGCCGCCTTTGTACTATCGAAACTCCTGAAGGTCCCAATA
TTGGTCTTATCTCTACACTCTGTGTACACGCTAAGATTAATAAAATGGGCTTTATCGAAACCCCCTACCGTAGCGTAACT
AAAGGAGGTAAGGTCGATCTCAAAAATGATCCCGTCTATCTCTCCGCAGAAGAAGAGGATTTTAAAACGATCGCTCAGGC
TAATACCACCCTTAGCAAAAAAGGCGTTTTCGATACCGATCGCGTGAAGTGCCGTAACCATGGCGACTTTCCCGTTCTCG
ATCCTTCTGACGACGAAATCGAATTCATCGATATCGCTCCTAACCAAATTGTAGGGGTCTCTGCCTCTATGATTCCTTTC
CTCTCTCATGATGATGCAAACCGTGCACTCATGGGCTCTAACATGCAGCGCCAAGCTGTACCCCTTCTTCGCCCTTCTGC
CCCTACCGTGGGTACCGGCCTAGAAGCTAAAGTAGCCCAAGATTCTCGTATGCTAATCAACGCAGAAGGATCTGGTGTGG
TCGAATATGTAGATGCTCGCAAAATCGTTATCCGATACGATAGAACCGATGAGCAACGCCTCACTTCTTTCGATGACGAT
TTGACAACCTATAACTTGGTGAAGTTCCGCAGAACTAACCAAAGTACTTGTATCAATATCAAACCTATCGTCCGCAAAGG
CGAAAAGGTCCATAAAGGCAAAATCCTCTGTGAAGGTTATGCTACCGATAATGGCGAACTCGCCCTCGGTCAAAACCTTA
AGGTGGCCTTTATGCCCTGGAAAGGGTACAACTTTGAGGATGCAATCGTGCTTTCTCAACGTGTAGTCCGTGAAGATATC
TTTACTTCTCTTCATATCGAGGAGTTCGAATTAGATGTCCGCGATACTAAACTAGGTGAAGAAGAATTTACCAACGATAT
CCCCAACGTTTCTGAAGAGGCCACTAAAGACTTGGATGAAAACGGTATCGTGCGCACCGGCGCATGGGTCCGCGATGGCG
ATATTATTATCGGTAAAATTACGCCCAAAGGCGAATCTGATCCTACCCCAGAAGAAAAGTTGCTCCGCGCAATTTTTGGC
GACAAGGCCGGAGATGTAAAAGATGCCTCTCTCAAAATGTCTCCCTCTGCTAAAGGGGTGATCATTGGCTCTCGCCTTTT
TGTCCGCGCCAAAAAGGATAAGGTCCAAAAGGCTAAAGACAAGCAAATGCTCGATAAATTAGAGCAGGAGCATAGCCAAG
AGATTAAAGAGCATACTCAAGTTCTCGTCGAGAAGTTGATGCAGGTCCTCGAAGGCCAAAATTCTGCCGGTGTCCGTAGT
ATCTATGCCGAATTGCTTATCCCCCAAGGTGCACCCTTTACTCAAAGAGCGCTTAAGGATATCGATTATAGCGCCGTAGA
TTACTCGAACTGGACAGAAGACGAGACCGTAAACAAACAGGTCCGCACCCTCTTGCACAATTATACCATTAAGCTTAATA
AAAAGATTAGTGTGTATAAGCGTAAGAAGTTTGCCATCAATATCGGTGACGAACTACCCGCCGGTGTCCTCAAATTGGCC
AAAGTATATATGGCCAAAAAGCGTAAGCTGAAAGTAGGGGATAAGTTGGCCGGTCGTCACGGTAACAAAGGTATTGTGGC
CCGCATCGTTCGCGATGAAGATATGCCTTTCCTCGAAGATGGAACACCTATGGACATCGTCCTTAACCCCCTAGGGGTAC
CCTCTCGTATGAACCTCGGACAGATCTTTGAAACTGTTCTGGGTTGGGCGGGCGAAAAACTCAATATGACTTTCGCTACT
CCCGTATTCGATGAGGCTAAGGTGCACCAAATTGAGGAATACGTACAAAAAGCTGGCTTGCCTAGCTATGGCGAAACTTA
TCTCTATGACGGAGAAACTGGCGACCGCTTCCACCAAAAAGCAACTGTCGGGGTGATCTACATGTTGAAACTCTCTCACA
TGGTAGACGATAAGATGCACGCCCGTTCTATCGGTCCTTACTCACTCATTACGCAGCAGCCCCTCGGTGGTAAAGCCCAG
TTTGGTGGTCAGCGTTTTGGTGAAATGGAGGTTTGGGCCCTAGAAGCATTCGGTGCCTCGCATATCCTACAAGAAATCTT
GACGATCAAATCTGACGATATTATCGGACGCGCCAAAGCTTACGAAACGATCGTTAAAGGCGATAACTTACCTACTCCCG
GTATTCCGGAATCATTCAATGTACTGGTACACGAACTTAGAGGTTTGGCCCTAGAAGTCAAGTTTGACTAA

Protein sequence : 
MAKSTTLTPKRPERFSFGKIQHDNHYPDFLEIQVKSFEEFFQLETTPESRFNEGLYQVFQENFPITDARNIFVLEFLNYF
IDPPRYTIDECMERGLTYSVPLKAKLRLSCNDEEHVDFEQTVQDVFLGNIPYMTPKGTFVINGAERVIVSQLHRSPGVFF
GQSRHPNGTKIYSARVIPFKGAWMEFATDINSVMYAYIDRKKKFPVTTLLRAIGYDGDRDILGLFGLADEVEATQEALEQ
HLGRKLAARVLRSWVEDFVDEDTGEVVSIERNEVILERDVILDEDNIQEVIDIGVDKVILQRENVEDDYSIIYNTLQKDT
SNSEIEAVQHIYRQLRGSDPPDDETARGIIDKLFFSDKRYSLGEVGRYKINRKLELDESNDTSVLTKEDIIAIVKYLVKL
INQKAEIDDIDHLSNRRVRTVGEQLYAQFGVGLARMARTIRERMNVRDNEVFTPVDLINARTLSSVINSFFGTSQLSQFL
DQTNPLSEITHKRRISALGPGGLSRERAGFEVRDVHYSHYGRLCTIETPEGPNIGLISTLCVHAKINKMGFIETPYRSVT
KGGKVDLKNDPVYLSAEEEDFKTIAQANTTLSKKGVFDTDRVKCRNHGDFPVLDPSDDEIEFIDIAPNQIVGVSASMIPF
LSHDDANRALMGSNMQRQAVPLLRPSAPTVGTGLEAKVAQDSRMLINAEGSGVVEYVDARKIVIRYDRTDEQRLTSFDDD
LTTYNLVKFRRTNQSTCINIKPIVRKGEKVHKGKILCEGYATDNGELALGQNLKVAFMPWKGYNFEDAIVLSQRVVREDI
FTSLHIEEFELDVRDTKLGEEEFTNDIPNVSEEATKDLDENGIVRTGAWVRDGDIIIGKITPKGESDPTPEEKLLRAIFG
DKAGDVKDASLKMSPSAKGVIIGSRLFVRAKKDKVQKAKDKQMLDKLEQEHSQEIKEHTQVLVEKLMQVLEGQNSAGVRS
IYAELLIPQGAPFTQRALKDIDYSAVDYSNWTEDETVNKQVRTLLHNYTIKLNKKISVYKRKKFAINIGDELPAGVLKLA
KVYMAKKRKLKVGDKLAGRHGNKGIVARIVRDEDMPFLEDGTPMDIVLNPLGVPSRMNLGQIFETVLGWAGEKLNMTFAT
PVFDEAKVHQIEEYVQKAGLPSYGETYLYDGETGDRFHQKATVGVIYMLKLSHMVDDKMHARSIGPYSLITQQPLGGKAQ
FGGQRFGEMEVWALEAFGASHILQEILTIKSDDIIGRAKAYETIVKGDNLPTPGIPESFNVLVHELRGLALEVKFD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00346 YP_008207811.1 DNA-directed RNA polymerase, beta subunit/140 kD subunit Not tested AbaR25 Protein 0.0 44
BJAB0868_00350 YP_008211676.1 DNA-directed RNA polymerase, beta subunit/140 kD subunit Not tested AbaR26 Protein 0.0 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta CP001918.1.gene250.p Protein 0.0 45
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_002695.1.914942.p Protein 0.0 45
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta CP001138.1.gene4362. Protein 0.0 45
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta CP000034.1.gene3741. Protein 0.0 45
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta CP000647.1.gene4402. Protein 0.0 45
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta CP004022.1.gene2794. Protein 0.0 44
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_002516.2.881699.p Protein 0.0 44
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_009085.4918494.p0 Protein 0.0 44
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta CP002695.1.gene18.p0 Protein 0.0 44
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_010410.6003841.p0 Protein 0.0 44
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_011586.7046027.p0 Protein 0.0 44
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_010400.5987325.p0 Protein 0.0 44
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_010611.6233925.p0 Protein 0.0 44
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_011595.7060572.p0 Protein 0.0 44
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_008702.1.4609796. Protein 0.0 44
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_011035.1.6448762. Protein 0.0 43
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta CP000675.2.gene392.p Protein 0.0 42
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_009782.5559150.p0 Protein 1e-165 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_002951.3236234.p0 Protein 2e-165 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_002953.2862188.p0 Protein 1e-165 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_013450.8613267.p0 Protein 1e-165 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_007793.3914836.p0 Protein 1e-165 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_003923.1002608.p0 Protein 1e-165 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_009641.5330265.p0 Protein 1e-165 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_009487.5169226.p0 Protein 1e-164 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_010079.5776819.p0 Protein 1e-165 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_002952.2860169.p0 Protein 2e-165 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_007622.3792928.p0 Protein 1e-165 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_002745.1123305.p0 Protein 1e-165 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_007795.3920377.p0 Protein 1e-165 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_009632.5315067.p0 Protein 1e-165 41
rpoB YP_005322623.1 DNA-directed RNA polymerase subunit beta NC_002758.1120515.p0 Protein 1e-164 41