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Name : ASU2_01880 (ASU2_01880) Accession : YP_006816757.1 Strain : Actinobacillus suis H91-0380 Genome accession: NC_018690 Putative virulence/resistance : Virulence Product : RTX-II toxin determinant A Function : - COG functional category : - COG ID : - EC number : - Position : 417162 - 420032 bp Length : 2871 bp Strand : + Note : COG2931 RTX toxins and related Ca2+-binding proteins DNA sequence : ATGTCAAAAATCACTTTGTCATCATTAAAATCGTCCTTACAACAAGGATTGAAAAATGGGAAAAACAAGTTAAATCAAGC AGGTACAACACTGAAGAATGGTTTAACTCAAACTGGTCATTCTCTACAGAATGGGGCTAAAAAATTAATCTTATATATTC CTCAAGGCTATGATTCGGGTCAAGGAAATGGAATTCAAGATTTAGTTAAAGCTGCTAATGATTTAGGTATTGAAGTATGG CGAGAAGAACGCAGCAATTTGGACATTGCAAAAACTAGCTTTGATACAACTCAGAAAATTCTAGGTTTTACTGATAGAGG AATTGTATTATTTGCACCTCAGCTAGATAATTTATTAAAGAAGAATCCTAAAATTGGCAATACATTAGGAAGTGCTTCTA GCATCTCACAAAATATAGGTAAAGCCAATACTGTATTAGGTGGTATTCAATCTATTTTAGGATCTGTTTTATCTGGAGTA AATCTGAATGAATTACTTCAAAATAAAGATCCTAATCAATTAGAACTTGCAAAAGCAGGGCTAGAACTGACTAATGAATT AGTTGGTAATATTGCTAGCTCGGTGCAAACTGTAGATGCATTTGCAGAACAAATATCTAAACTAGGTTCACATTTACAGA ATGTGAAAGGATTAGGAGGATTGAGTAATAAATTACAAAATCTACCAGATCTAGGAAAAGCAAGTTTAGGTTTGGACATT ATCTCTGGTTTACTTTCTGGAGCATCTGCAGGTCTCATTTTAGCAGATAAAAAGGCTTCAACAGAAAAGAAAGCTGCCGC AGGTGTAGAATTTGCTAACCAAATTATAGGTAATGTAACAAAAGCGGTCTCATCTTACATTCTTGCCCAACGAGTCGCTT CAGGTTTGTCTTCAACTGGTCCTGTCGCTGCATTAATCGCATCTACAGTTGCACTAGCTGTTAGCCCTCTTTCATTCTTA AATGTAGCTGATAAGTTTAAACAAGCTGATTTAATCAAATCATATTCTGAACGCTTCCAAAAATTAGGATATGATGGAGA TCGTTTATTAGCTGATTTTCACCGTGAGACAGGAACTATTGATGCTTCTGTAACAACAATTAACACTGCTTTAGCAGCTA TCTCCGGTGGAGTTGGAGCTGCAAGCGCGGGTTCTCTAGTCGGAGCTCCAGTTGCGTTACTCGTTGCTGGTGTTACGGGA CTTATTACAACTATTCTAGAATATTCTAAACAAGCCATGTTTGAACATGTTGCAAATAAGGTTCATGACAGAATAGTTGA ATGGGAGAAAAAACATAATAAAAACTATTTTGAGCAAGGTTATGATTCTCGTCATTTAGCTGATTTACAAGACAATATGA AGTTTCTTATCAATTTAAATAAAGAACTTCAGGCTGAACGCGTAGTAGCTATTACCCAACAAAGATGGGATAACCAAATT GGAGACCTAGCGGCAATTAGCCGTAGAACGGATAAAATTTCCAGTGGAAAAGCTTATGTGGATGCTTTTGAGGAGGGGCA ACACCAGTCCTACGATTCATCCGTACAGCTAGATAACAAAAACGGTATTATTAATATTAGTAATACAAATAGAAAGACAC AAAGTGTTTTATTCAGAACTCCATTACTAACTCCAGGTGAAGAGAATCGGGAACGTATTCAGGAAGGTAAAAATTCTTAT ATTACAAAATTACATATACAAAGAGTTGACAGTTGGACTGTAACAGATGGTGATGCTAGCTCAAGCGTAGATTTCACTAA TGTAGTACAACGAATCGCTGTGAAATTTGATGATGCAGGTAACATTATCGAATCTAAAGATACTAAAATTATCGCAAATT TAGGTGCTGGTAACGATAATGTATTTGTTGGGTCAAGTACTACCGTTATTGATGGCGGGGACGGACATGATCGAGTTCAC TACAGTAGAGGAGAATATGGCGCATTAGTTATTGATGCTACAGCCGAGACAGAAAAAGGCTCATATTCAGTAAAACGCTA TGTCGGAGACAGTAAAGCATTACATGAAACAATTGCCACCCACCAAACAAATGTTGGTAATCGTGAAGAAAAAATTGAAT ATCGTCGTGAAGATGATCGTTTTCATACTGGTTATACTGTGACGGACTCACTCAAATCAGTTGAAGAGATCATTGGTTCA CAATTTAATGATATTTTCAAAGGAAGCCAATTTGATGATGTGTTCCATGGTGGTAATGGTGTAGACACTATTGATGGTAA CGATGGTGACGATCATTTATTTGGTGGCGCAGGCGATGATGTTATCGATGGAGGAAACGGTAACAATTTCCTTGTTGGAG GAACCGGTAATGATATTATCTCGGGAGGTAAAGATAATGATATTTATGTCCATAAAACAGGCGATGGAAATGATTCTATT ACAGACTCTGGCGGACAAGATAAACTGGCATTTTCGGATGTAAATCTTAAAGACCTCACCTTTAAGAAAGTAGATTCTTC TCTCGAAATCATTAATCAAAAAGGAGAAAAAGTTCGTATTGGGAATTGGTTCTTAGAAGATGATTTGGCTAGCACAGTTG CTAACTATAAAGCTACGAATGACCGAAAAATTGAGGAAATTATTGGTAAAGGAGGAGAACGTATTACATCAGAACAAGTT GATAAACTGATTAAGGAGGGTAACAATCAAATCTCTGCAGAAGCATTATCCAAAGTTGTGAATGATTACAATACGAGTAA AGATAGACAGAACGTATCTAATAGCTTAGCAAAATTGATTTCTTCAGTCGGGAGCTTTACGTCTTCCTCAGACTTTAGGA ATAATTTAGGAACATATGTTCCTTCATCAATAGATGTCTCGAATAATATTCAATTAGCTAGAGCCGCTTAA Protein sequence : MSKITLSSLKSSLQQGLKNGKNKLNQAGTTLKNGLTQTGHSLQNGAKKLILYIPQGYDSGQGNGIQDLVKAANDLGIEVW REERSNLDIAKTSFDTTQKILGFTDRGIVLFAPQLDNLLKKNPKIGNTLGSASSISQNIGKANTVLGGIQSILGSVLSGV NLNELLQNKDPNQLELAKAGLELTNELVGNIASSVQTVDAFAEQISKLGSHLQNVKGLGGLSNKLQNLPDLGKASLGLDI ISGLLSGASAGLILADKKASTEKKAAAGVEFANQIIGNVTKAVSSYILAQRVASGLSSTGPVAALIASTVALAVSPLSFL NVADKFKQADLIKSYSERFQKLGYDGDRLLADFHRETGTIDASVTTINTALAAISGGVGAASAGSLVGAPVALLVAGVTG LITTILEYSKQAMFEHVANKVHDRIVEWEKKHNKNYFEQGYDSRHLADLQDNMKFLINLNKELQAERVVAITQQRWDNQI GDLAAISRRTDKISSGKAYVDAFEEGQHQSYDSSVQLDNKNGIINISNTNRKTQSVLFRTPLLTPGEENRERIQEGKNSY ITKLHIQRVDSWTVTDGDASSSVDFTNVVQRIAVKFDDAGNIIESKDTKIIANLGAGNDNVFVGSSTTVIDGGDGHDRVH YSRGEYGALVIDATAETEKGSYSVKRYVGDSKALHETIATHQTNVGNREEKIEYRREDDRFHTGYTVTDSLKSVEEIIGS QFNDIFKGSQFDDVFHGGNGVDTIDGNDGDDHLFGGAGDDVIDGGNGNNFLVGGTGNDIISGGKDNDIYVHKTGDGNDSI TDSGGQDKLAFSDVNLKDLTFKKVDSSLEIINQKGEKVRIGNWFLEDDLASTVANYKATNDRKIEEIIGKGGERITSEQV DKLIKEGNNQISAEALSKVVNDYNTSKDRQNVSNSLAKLISSVGSFTSSSDFRNNLGTYVPSSIDVSNNIQLARAA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hlyA | NP_755445.1 | hemolysin A | Virulence | PAI I CFT073 | Protein | 4e-149 | 49 |
| hlyA | CAD33759.1 | hemolysin A | Virulence | PAI I 536 | Protein | 2e-146 | 49 |
| hlyA | CAD42039.1 | HlyA protein | Virulence | PAI II 536 | Protein | 1e-147 | 48 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ASU2_01880 | YP_006816757.1 | RTX-II toxin determinant A | VFG1500 | Protein | 1e-146 | 49 |
| ASU2_01880 | YP_006816757.1 | RTX-II toxin determinant A | VFG0906 | Protein | 2e-149 | 49 |
| ASU2_01880 | YP_006816757.1 | RTX-II toxin determinant A | VFG1558 | Protein | 6e-148 | 48 |
| ASU2_01880 | YP_006816757.1 | RTX-II toxin determinant A | VFG0840 | Protein | 1e-145 | 45 |
