Gene Information

Name : cysB (J451_05510)
Accession : YP_008222483.1
Strain : Mannheimia haemolytica D174
Genome accession: NC_021739
Putative virulence/resistance : Unknown
Product : CysB family transcriptional regulator
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1066810 - 1067793 bp
Length : 984 bp
Strand : -
Note : LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes

DNA sequence : 
ATGAAGCTACAACAGTTACGTTATATCGTTGAAATAGTAAACCAGAACTTGAATATTACCGAGGCCGCAGAGGTGCTTTA
CACTTCTCAACCGGGGATTAGCAAACAAGTTCGTTTGTTGGAAAGTGAGTTGGGAATTAATATTTTTGAGCGTAACGGTA
AGCACGTTAAGGGGCTAACGCCTGCTGGTGAAAAAATTGTGGCGATTGCTCGTGAATTATTGGTAAAAGCCCAGAGCATT
AAATCGGTTGCTGAAGAACAAACTCGACCCAACAAAGGCATCTTACGCATTGCGACCACCAATACCCAAGCCCGTTATAT
GCTACCGAGTGTAATTGAGAAGTTTAAGGCTCGCTATCCTGAAGTAAGTTTGCATTTGCACCAAGGCTCCCCGAATCAAA
TTTATGATGCTTTGGTGGCTGGAGAAGTGGATTTAGCCATTACCACAGAAGCTCAATATTTATTTGATGAAGCGGTTTTA
TTGCCGTGTTATTGGTGGAATCGTTCAGTTATTGTCAAACCAGAGCATCCTCTTGCGGCTTTTGTGAACCAAAGTAAAAA
TTTGACTGTCGAACAATTAGGTAGATATGATTTGATAACCTATACTTTTGGTTTTACAGGGCAATCGGATTTAGATCATG
CCTTCAATAAGGAAGGTATTTTGCCTAATATCGTATTTACGGCGACAGATGCTGATGTAATCAAAACTTATGTACGCTTA
GGCTTAGGGGTTGGTATTATGGCATCAATGGCACATACGGAAACGGATAAAGACTTAGTCGCTATCAATGCAAGTCACCT
GTTTCAACCGAGTATGACGCAAATCGCCTTTAAACGAGGAACTTTTCTTCGTAACTATATGTATGATTTTATTAATTATT
TTTCGCCACATTTAACACGGGTACAAGTGGAGAAAGCGGAACAATTACGAGATAACAATGCAATTTCAAGGTTGTTCGAA
AGTATATCTTTAGAGGAGAAATAG

Protein sequence : 
MKLQQLRYIVEIVNQNLNITEAAEVLYTSQPGISKQVRLLESELGINIFERNGKHVKGLTPAGEKIVAIARELLVKAQSI
KSVAEEQTRPNKGILRIATTNTQARYMLPSVIEKFKARYPEVSLHLHQGSPNQIYDALVAGEVDLAITTEAQYLFDEAVL
LPCYWWNRSVIVKPEHPLAAFVNQSKNLTVEQLGRYDLITYTFGFTGQSDLDHAFNKEGILPNIVFTATDADVIKTYVRL
GLGVGIMASMAHTETDKDLVAINASHLFQPSMTQIAFKRGTFLRNYMYDFINYFSPHLTRVQVEKAEQLRDNNAISRLFE
SISLEEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cbl YP_853089.1 transcriptional regulator Cbl Not tested PAI IV APEC-O1 Protein 2e-54 41