Gene Information

Name : yedW (SDY_1039)
Accession : YP_402695.2
Strain : Shigella dysenteriae Sd197
Genome accession: NC_007606
Putative virulence/resistance : Virulence
Product : transcriptional regulatory protein YedW
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 981069 - 981719 bp
Length : 651 bp
Strand : +
Note : induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistanc

DNA sequence : 
ATGAAGATTTTACTTATTGAAGATAATCAAAGGACCCAGGAGTGGGTAACGCAGGGGCTTTCCGAAGCGGGTTATGTCAT
TGATGCCGTTTCTGATGGCAGAGATGGGCTTTATCTTGCGCTGAAGGATGATTATGCATTGATCATTCTGGATATTATGC
TTCCGGGTATGGATGGCTGGCAGATCTTACAAACGTTAAGAACGGCAAAGCAAACCCCTGTTATTTGCCTTACTGCAAGG
GATTCTGTCGATGACAGAGTCAGAGGGCTGGACAGTGGAGCAAATGATTATCTGGTAAAACCTTTTTCATTTTCTGAGTT
GCTGGCAAGGGTTCGGGCACAATTAAGGCAACATCACGCTTTGAATTCAACATTAGAAATCAGCGGCTTAAGAATGGACT
CTGTTAGTCAAAGTGTGAGCAGGGACAATATCAGTATTACACTGACGCGCAAGGAGTTTCAGTTACTTTGGCTACTGGCC
TCCAGAGCTGGCGAAATTATACCCAGAACGGTTATTGCGAGTGAAATTTGGGGAATCAACTTTGATAGTGATACCAATAC
GGTGGATGTCGCCATTCGCAGGCTCCGCGCAAAAGTTGATGATCCTTTTCCGGTGATGCTTCCAATTAGTAGAACATGTG
TTTTTCAATAA

Protein sequence : 
MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQILQTLRTAKQTPVICLTAR
DSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQHHALNSTLEISGLRMDSVSQSVSRDNISITLTRKEFQLLWLLA
SRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPVMLPISRTCVFQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 3e-75 76
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-74 74

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yedW YP_402695.2 transcriptional regulatory protein YedW BAC0125 Protein 2e-53 55
yedW YP_402695.2 transcriptional regulatory protein YedW BAC0197 Protein 2e-51 54
yedW YP_402695.2 transcriptional regulatory protein YedW BAC0083 Protein 4e-51 53
yedW YP_402695.2 transcriptional regulatory protein YedW BAC0308 Protein 2e-48 50
yedW YP_402695.2 transcriptional regulatory protein YedW BAC0638 Protein 2e-45 50
yedW YP_402695.2 transcriptional regulatory protein YedW BAC0111 Protein 1e-51 49
yedW YP_402695.2 transcriptional regulatory protein YedW BAC0347 Protein 1e-46 48
yedW YP_402695.2 transcriptional regulatory protein YedW NC_002951.3238224.p0 Protein 8e-35 41
yedW YP_402695.2 transcriptional regulatory protein YedW NC_007793.3914065.p0 Protein 8e-35 41
yedW YP_402695.2 transcriptional regulatory protein YedW NC_002758.1121390.p0 Protein 8e-35 41
yedW YP_402695.2 transcriptional regulatory protein YedW NC_010079.5776364.p0 Protein 8e-35 41
yedW YP_402695.2 transcriptional regulatory protein YedW NC_002952.2859858.p0 Protein 8e-35 41
yedW YP_402695.2 transcriptional regulatory protein YedW NC_007622.3794948.p0 Protein 8e-35 41
yedW YP_402695.2 transcriptional regulatory protein YedW NC_003923.1003417.p0 Protein 8e-35 41
yedW YP_402695.2 transcriptional regulatory protein YedW NC_013450.8614146.p0 Protein 8e-35 41
yedW YP_402695.2 transcriptional regulatory protein YedW BAC0487 Protein 6e-26 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yedW YP_402695.2 transcriptional regulatory protein YedW VFG0596 Protein 1e-75 76