Gene Information

Name : APECO78_06430 (APECO78_06430)
Accession : YP_007380463.1
Strain : Escherichia coli APEC O78
Genome accession: NC_020163
Putative virulence/resistance : Virulence
Product : DNA-binding transcriptional activator CusR
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1316042 - 1316725 bp
Length : 684 bp
Strand : -
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence : 
ATGAAACTGTTGATTGTCGAAGATGAAAAGAAAACCGGAGAATACTTGACCAAAGGGTTAACCGAAGCCGGTTTTGTGGT
CGATTTGGCCGACAACGGGTTGAATGGCTACCATCTGGCGATGACCGGTGATTATGATCTGATAATCCTCGATATTATGC
TGCCGGACGTGAACGGCTGGGATATCGTGCGCATGTTGCGTTCCGCCAATAAAGGGATGCCGATTCTGTTGCTTACCGCG
CTTGGCACCATTGAACATCGCGTCAAGGGGCTGGAGTTGGGGGCGGATGACTATCTGGTGAAGCCGTTCGCTTTTGCTGA
ACTGCTGGCGCGGGTGCGCACTCTCCTGCGGCGCGGGGCGGCGATGATTATCGAAAGTCAGTTTCAGGTTGCCGATCTGA
TGGTCGATCTCGTCAGCCGCAAAGTCACCCGCAGCGGCACGCGCATCACTCTGACCAGTAAAGAGTTTACTCTGCTGGAG
TTTTTCCTCCGCCATCAGGGCGAAGTGCTGCCCCGCTCGCTTATCGCCTCGCAGGTGTGGGACATGAATTTCGACAGCGA
CACTAACGCCATTGATGTAGCGGTGAAGCGGCTGCGCGGCAAAATCGACAACGACTTTGAGCCGAAGCTAATTCAGACCG
TGCGCGGCGTGGGCTACATGCTTGAGGTGCCGGATGGTCAGTAA

Protein sequence : 
MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTA
LGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRRGAAMIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVGYMLEVPDGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 4e-56 53
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 7e-56 52

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR BAC0111 Protein 1e-103 99
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR BAC0347 Protein 7e-88 83
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR BAC0083 Protein 8e-71 62
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR BAC0638 Protein 3e-63 62
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR BAC0308 Protein 7e-64 60
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR BAC0197 Protein 6e-64 59
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR BAC0125 Protein 3e-64 56
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR AE000516.2.gene3505. Protein 2e-27 42
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR NC_002951.3238224.p0 Protein 8e-35 41
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR NC_007793.3914065.p0 Protein 8e-35 41
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR NC_002758.1121390.p0 Protein 8e-35 41
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR NC_010079.5776364.p0 Protein 8e-35 41
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR NC_002952.2859858.p0 Protein 8e-35 41
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR NC_007622.3794948.p0 Protein 8e-35 41
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR NC_003923.1003417.p0 Protein 8e-35 41
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR NC_013450.8614146.p0 Protein 8e-35 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR VFG0596 Protein 2e-56 53
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR VFG1390 Protein 3e-43 43
APECO78_06430 YP_007380463.1 DNA-binding transcriptional activator CusR VFG1389 Protein 7e-34 41