Gene Information

Name : aldB (TepiRe1_0142)
Accession : YP_007270807.1
Strain : Tepidanaerobacter acetatoxydans Re1
Genome accession: NC_019954
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase B
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.22
Position : 148886 - 150361 bp
Length : 1476 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7768815; Product type e : enzyme

DNA sequence :
TTGAATAAACCTATTGACAAAAATTATCAATTGTTAATTGGAGGTCGATGGGTGGATGCAAAGGATGGGGAGACGTTTGA
GACTAACAACCCGGCAAATGGCGAGCTGTTAGCAACTTGTGCCAATGCCGGTAAGGAAGATGTGGATGAAGCAGTTAAAG
CTGCATGGAAGGCATTTGAAACGTGGAAAGATGTTAGTGCACAAGAAAAATCAGGAATATTACTTAAAATAGCCGATCTG
ATTGATGAAAATGCTGAAAAACTTGCTATGATTGAAACTCTCGACAACGGTAAACCCATTCGAGAAACACGAAACATTGA
TGTGCCGCTAAGTTCTGATCATTTTCGGTATTTTGCCGGAGCTATCAGGGCTGAAGAAGGCCAAGCCGTAATGATTGACA
AGAACACCTTAAGCATTATCTTAAGAGAGCCGATTGGAGTTGTCGGCCAGATAATTCCATGGAACTTCCCGCTGCTGATG
GCGGCATGGAAGTTGGCACCAGCATTGGCTGCAGGATGTACGGTTGTTATTAAGCCGTCGTCTTCAACACCTTTGAGCAT
TTTAGAATTAGGTAAATTGATCAATGATGTTCTTCCCCCGGGAGTTGTGAACATCGTAACTGGCAGCGGAGCCACCACAG
GAAATTATATGTTGGAACATCCGGGATTTAGAAAACTTGCCTTTACAGGTTCAACCGAAGTAGGCTACAGTATAGCCGAG
GCGGCAGCTAAAAAGTTGATTCCGTCAACACTAGAGCTTGGTGGAAAATCCGCAAATATTTATTTCCCAGACTGCCCATG
GGAGAAGGCTATAGAAGGGGTGCAACTGGGCATCTTGTTCAATCAAGGGCAAGTTTGCTGCGCAGGCTCCAGGGTATTTG
TGCATGAAGATATTTATGAAGAATTCCTTGCAGAATGTGTTGAAGCCTTTAAGAAAATCAAGGTTGGTTTGCCATGGGAA
GAAGATACTATTATGGGAACGCAGATTAATGAAGGTCAGTTGAAAAAGATTTTAAACTATATTGAAATTGGAAAACAAGA
AGGGGCAAGACTTGCCTGCGGCGGTTCTCGCATCACTGAAAATGGCTTAGATAAAGGATGCTTTATGCAGCCTACGATTT
TTGCCGATGTTGATAACAAAATGAGGATTGCTCAAGAAGAGATTTTTGGGCCGGTAGCATGTTTCTTGAAGTTTAAGGAT
GAAGAAGAAGTAATAAAAATGGCAAATGACAGCGAATACGGATTGGGCGGCGCTGTGTGGACTAAGGATATAAACAGGGC
GCTTAAAGTTGCAAGAGGAATAGAGACAGGCCGTATGTGGATAAATGATTATAACAACCTGCCTGCTCATACTCCCTTCG
GAGGCTATAAGAAATCCGGAATTGGCCGCGAAACTCACCATATGATGCTTGACCATTATACTCAGAAGAAGAATATAATG
ATAAGTATGAATGAAAATAAGGCTGGCTTATACTAA

Protein sequence :
MNKPIDKNYQLLIGGRWVDAKDGETFETNNPANGELLATCANAGKEDVDEAVKAAWKAFETWKDVSAQEKSGILLKIADL
IDENAEKLAMIETLDNGKPIRETRNIDVPLSSDHFRYFAGAIRAEEGQAVMIDKNTLSIILREPIGVVGQIIPWNFPLLM
AAWKLAPALAAGCTVVIKPSSSTPLSILELGKLINDVLPPGVVNIVTGSGATTGNYMLEHPGFRKLAFTGSTEVGYSIAE
AAAKKLIPSTLELGGKSANIYFPDCPWEKAIEGVQLGILFNQGQVCCAGSRVFVHEDIYEEFLAECVEAFKKIKVGLPWE
EDTIMGTQINEGQLKKILNYIEIGKQEGARLACGGSRITENGLDKGCFMQPTIFADVDNKMRIAQEEIFGPVACFLKFKD
EEEVIKMANDSEYGLGGAVWTKDINRALKVARGIETGRMWINDYNNLPAHTPFGGYKKSGIGRETHHMMLDHYTQKKNIM
ISMNENKAGLY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-102 54
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-106 54
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-106 54
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-106 54
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-105 54
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-76 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldB YP_007270807.1 aldehyde dehydrogenase B VFG0082 Protein 1e-102 54