Gene Information

Name : Closa_1722 (Closa_1722)
Accession : YP_003821941.1
Strain : Clostridium saccharolyticum WM1
Genome accession: NC_014376
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 1838603 - 1840090 bp
Length : 1488 bp
Strand : +
Note : PFAM: Aldehyde Dehydrogenase; KEGG: dds:Ddes_1981 aldehyde dehydrogenase

DNA sequence :
TTGCAGAATGTAGAGCTTCTAAAGAAATATCAGTTATTCATAGGCGGGCAATGGAAGGATGCTTCCGATGGAAAAACATT
TCCGACAATCTGCCCGGCCGATGGGAGGGTGCTGACTGAGTGCGCTGAGGCAACAAAGGATGACGTGGATGAGGCGGTCC
GGGAAGCATGGAAGGCATTTGAAACCTGGAAGAATGTACCGGTAAACCAGAGAGCTGCCATTCTGAATAAGATTGCGGAT
ATCATAGATGCGAATAAGGAACATCTTGCCATGGTGGAAACCCTGGACAACGGGAAACCCATAAGGGAAACCTTGACGGT
GGATATACCTCTTGGTGCCCAGCATTTCCGCTATTTTGCAGGCTGTATTATGGCGGAAGAGGGCAGTGCCAGTATACTGG
GAGAAAATATCTTAAGTCTGATCCTGAAAGAACCGATCGGCGTGGTTGGGCAGATCGTTCCCTGGAATTTCCCATTCCTG
ATGGCAGCCTGGAAGCTGGCACCGGTACTGGCAAGCGGCTGCTGTTCCGTCTTTAAGACCTCCAGCACCACTTCTCTCAG
CGTTCTGGAACTGGCAAGGCTAATCCAGGATGTGATCCCGGCCGGGGTGTTTAATGTGATTACCGGAGCGGGTTCCAAGT
CCGGGCAATATATGTTGGAACATGAAGGATTCCGGAAGCTTGCATTTACCGGCTCAACGGAAGTCGGAAAGAACGTGGCC
CTAGCAGCAGCGGAAAAGCTGATTCCGGCTACTTTGGAGCTGGGCGGCAAATCGGCTAATATTTACTTTGAGGACTGTGA
TTGGGAGATGGCCATGGATGGCTTACAGCTGGGGATTCTCTTTAACCAGGGCCAGGTATGCTGTGCGGGTTCCAGGGTCT
TTGTGCAGGAAAGCATTTACGATAAGTTTGTGGAAGAAGCGGTTAAACGGTTTAACCAGGTAAAGGTCGGTCTTCCGTGG
GATGAACATACCCAGATGGGAAGTCAGATCAGCAAAGGGCATATGAAGGATATTTTAAGCTACATAGAGATTGGAAAATC
AGAAGGAGCGGCAGTGCTTTGCGGCGGAGAGCAGATTCTGGAGGACGGACTGGAAAACGGAGCATTTTTAAGGCCTACGC
TCCTTGGCAATGTGACAAATGACATGAGGGTGGCACAAGAAGAGATCTTCGGACCTGTGGCATGTATCATTAAGTTTAAG
ACAGAGGATGAGGCCGTGGCTATGGCCAATGACAGCCAGTACGGACTGGGTGGAGCAGTATGGACCAGAGACATCAATCG
GGCAATACGGGTTGCCAGAGCGGTGGAGACCGGACGTATGTGGGTTAATACCTATAATTCCATTCCTGAGGGAGCTCCTT
TCGGGGGATACAAGACTTCGGGAATCGGCCGTGAGACACATAAGGTCATTCTGGAACACTACACCCAGACAAAGAATATC
ATGATCAATTTAACTGAATCTCCTTCCGGTTTTTATCCGGTTAAATAA

Protein sequence :
MQNVELLKKYQLFIGGQWKDASDGKTFPTICPADGRVLTECAEATKDDVDEAVREAWKAFETWKNVPVNQRAAILNKIAD
IIDANKEHLAMVETLDNGKPIRETLTVDIPLGAQHFRYFAGCIMAEEGSASILGENILSLILKEPIGVVGQIVPWNFPFL
MAAWKLAPVLASGCCSVFKTSSTTSLSVLELARLIQDVIPAGVFNVITGAGSKSGQYMLEHEGFRKLAFTGSTEVGKNVA
LAAAEKLIPATLELGGKSANIYFEDCDWEMAMDGLQLGILFNQGQVCCAGSRVFVQESIYDKFVEEAVKRFNQVKVGLPW
DEHTQMGSQISKGHMKDILSYIEIGKSEGAAVLCGGEQILEDGLENGAFLRPTLLGNVTNDMRVAQEEIFGPVACIIKFK
TEDEAVAMANDSQYGLGGAVWTRDINRAIRVARAVETGRMWVNTYNSIPEGAPFGGYKTSGIGRETHKVILEHYTQTKNI
MINLTESPSGFYPVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-106 50
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 9e-111 50
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 9e-111 50
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 9e-111 50
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-110 50
hpaE AAO17179.1 HpaE Not tested tcd island Protein 9e-81 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Closa_1722 YP_003821941.1 aldehyde dehydrogenase VFG0082 Protein 1e-106 50