Gene Information

Name : Msil_0189 (Msil_0189)
Accession : YP_002360532.1
Strain : Methylocella silvestris BL2
Genome accession: NC_011666
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 194126 - 194821 bp
Length : 696 bp
Strand : +
Note : PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bid:Bind_2236 two component transcriptional regulator, winged helix family

DNA sequence : 
ATGATGCCGTCCATGCGCATTCTCATCGTCGAAGATGATTCGGAAGCGGCCAATTACATGGCCAAGGCGTTCCGTGAGGC
GGGACATGTCGCCGACCATGTCGGCGACGGTCTCGAAGGCTACGCCCGGGCCCGCGAAGAGGATTACGACGTCCTCATCG
TCGACCGCATGTTGCCGAAGCTCGACGGCCTGTCGCTGATCGGCGGGTTGCGGGCGCAGAAAGTCGAAACGCCGGTGCTG
ATCCTTTCGGCGCTGGGGCAGGTCGACGACCGCGTCAAGGGCCTCAGGGCAGGGGGCGACGACTATCTCTCAAAGCCCTA
CGCCTTCGCCGAACTTCTCGCCCGCGTCGAAATCCTGGCCCGGCGCAAGCAGAATGGGACGGGTGAAGAGACCGTCTATC
GCGTCGGCGGTCTCGAGCTTGACCGGCTGGCGCATAAGGTTGCGCGCGAAGGCAAGGAGATCCAGTTGCAGCCGCGCGAG
TTCCGGCTGCTCGAATATCTGATGCGGCATGCGGGGCAGGTGGTGACGCGCACCATGCTTTTGGAGAATGTCTGGGACTA
TCATTTCGACCCCCAGACCAATGTCATCGACGTCCATATCTCCCGCCTGCGCAGCAAGATCGACAAGGGCTTTGAACCGC
CCCTTCTGCAGACCATTCGCGGCGCGGGATATATGATCCGTGACGGCTCTCGCTAA

Protein sequence : 
MMPSMRILIVEDDSEAANYMAKAFREAGHVADHVGDGLEGYARAREEDYDVLIVDRMLPKLDGLSLIGGLRAQKVETPVL
ILSALGQVDDRVKGLRAGGDDYLSKPYAFAELLARVEILARRKQNGTGEETVYRVGGLELDRLAHKVAREGKEIQLQPRE
FRLLEYLMRHAGQVVTRTMLLENVWDYHFDPQTNVIDVHISRLRSKIDKGFEPPLLQTIRGAGYMIRDGSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-39 43
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-38 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Msil_0189 YP_002360532.1 winged helix family two component transcriptional regulator BAC0111 Protein 2e-53 48
Msil_0189 YP_002360532.1 winged helix family two component transcriptional regulator BAC0197 Protein 1e-45 48
Msil_0189 YP_002360532.1 winged helix family two component transcriptional regulator BAC0125 Protein 2e-47 47
Msil_0189 YP_002360532.1 winged helix family two component transcriptional regulator BAC0347 Protein 2e-48 47
Msil_0189 YP_002360532.1 winged helix family two component transcriptional regulator BAC0083 Protein 2e-47 47
Msil_0189 YP_002360532.1 winged helix family two component transcriptional regulator BAC0308 Protein 2e-45 46
Msil_0189 YP_002360532.1 winged helix family two component transcriptional regulator BAC0638 Protein 5e-40 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Msil_0189 YP_002360532.1 winged helix family two component transcriptional regulator VFG0596 Protein 4e-40 43
Msil_0189 YP_002360532.1 winged helix family two component transcriptional regulator VFG1389 Protein 5e-36 43