Gene Information

Name : y2307 (y2307)
Accession : NP_669615.1
Strain : Yersinia pestis KIM
Genome accession: NC_004088
Putative virulence/resistance : Virulence
Product : two-component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2542389 - 2543081 bp
Length : 693 bp
Strand : +
Note : residues 1 to 228 of 230 are 53.27 pct identical to residues 1 to 227 of 227 from E. coli K12 : B0571; residues 1 to 224 of 230 are 66.51 pct identical to residues 1 to 223 of 229 from GenPept : >gb|AAG04826.1|AE004573_5 (AE004573) probable two-component

DNA sequence : 
ATGCGGCTATTGTTGGTAGAAGATGAGGAGAAGACATCTTCGTATATCAATCGCGCCCTCAGCGAGTTGGGCTTTACCGT
CGATGTAGCGGCCACCGGGATCGACGGATTATATCTGGCTCTTGAGTATGATTACGATACGATTGTGCTCGATGTCATGT
TGCCCGGCATGGATGGTTACAGCGTTCTCGAAGGCCTACGCGCCAGCAAACAAACTCCGGTTCTGATGTTATCCGCCCGT
GGCTCGGTTGATGAACGAGTTAAGGGCCTGCGTCACGGTGCCGACGATTATTTGCCTAAGCCTTTTTCGCTGATTGAACT
GGTTGCGCGTATCCAGGCGTTGTTGAGGCGGCGTCCCAGTGATGGTGTAGATGTCAGCCAATTGCACATTAATGATCTAC
ATCTCGACCTGCTGGCAAGGCGTGTCACGCGAGCCGGTGAACGTCTTGAACTCACCGCCAAAGAGTTCGCCCTGTTAAGC
CTGTTAGCCAGACATCAGGGGGAAATTCTGTCAAAAATGATGATTGCAGAGCAGGTCTGGGACATGAATTTTGACAGCGA
TGCTAATGTCGTTGAGGTGGCGATAAAACGCCTGCGGGCGAAAATAGATACGCCCTACCCGGTCAAACTGCTGCATACAG
TGCGAGGCATGGGGTATGTCCTTGAAACTCGCCCCGATCGCCAGACTAAATAG

Protein sequence : 
MRLLLVEDEEKTSSYINRALSELGFTVDVAATGIDGLYLALEYDYDTIVLDVMLPGMDGYSVLEGLRASKQTPVLMLSAR
GSVDERVKGLRHGADDYLPKPFSLIELVARIQALLRRRPSDGVDVSQLHINDLHLDLLARRVTRAGERLELTAKEFALLS
LLARHQGEILSKMMIAEQVWDMNFDSDANVVEVAIKRLRAKIDTPYPVKLLHTVRGMGYVLETRPDRQTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 8e-54 50
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 1e-52 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
y2307 NP_669615.1 two-component transcriptional regulator BAC0083 Protein 2e-62 61
y2307 NP_669615.1 two-component transcriptional regulator BAC0197 Protein 4e-60 58
y2307 NP_669615.1 two-component transcriptional regulator BAC0638 Protein 7e-53 57
y2307 NP_669615.1 two-component transcriptional regulator BAC0125 Protein 8e-61 56
y2307 NP_669615.1 two-component transcriptional regulator BAC0111 Protein 1e-59 53
y2307 NP_669615.1 two-component transcriptional regulator BAC0347 Protein 1e-52 51
y2307 NP_669615.1 two-component transcriptional regulator BAC0308 Protein 3e-52 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
y2307 NP_669615.1 two-component transcriptional regulator VFG0596 Protein 3e-54 50
y2307 NP_669615.1 two-component transcriptional regulator VFG1389 Protein 2e-38 48
y2307 NP_669615.1 two-component transcriptional regulator VFG1390 Protein 3e-40 44
y2307 NP_669615.1 two-component transcriptional regulator VFG1386 Protein 5e-35 43