Gene Information

Name : safC (SPA2462)
Accession : YP_151652.1
Strain : Salmonella enterica ATCC 9150
Genome accession: NC_006511
Putative virulence/resistance : Virulence
Product : outer-membrane fimbrial usher protein
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 2559697 - 2562207 bp
Length : 2511 bp
Strand : -
Note : similar to Salmonella typhi CT18 outer-membrane fimbrial usher protein

DNA sequence :
ATGAAGTTCAAACAACCTGCCTTGCTACTGTTTATCGCGGGAGTGGTTCACTGCGCAAATGCGCACGCTTACACATTCGA
TGCATCAATGTTGGGCGATGCAGCGAAAGGGGTTGATATGTCGCTCTTTAACCAGGGGGTACAACAGCCAGGGACTTATC
GAGTGGACGTAATGGTGAATGGTAAACGTGTCGACACCCGTGATGTGGTGTTCAAATTAGAAAAGGATGGGCAAGGAACG
CCTTTTCTGGCTTCTTGTTTGACGGTCAGTCAGCTTTCACGCTACGGCGTAAAAACGGAAGATTACCCTCAGTTGTGGAA
AGCAGCAAAGCCCCCAGATGAGTGTGCGGATCTGACCGCCATTCCACAGGCTAAAGCGGTACTGGATATCAATAATCAGC
AACTGCAACTGAGTATTCCGCAGTTGGCGTTGCGTCCGGAATTTAAGGGGATCGCTCCTGAAGATATCTGGGATGATGGT
ATTCCGGCGTTTCTGATGAACTACAGTGCGAGGACAACGCAGACGGATTACAAAATGGATATGGAGAGGCGTGACAACTC
TTCCTGGGTACAACTGCAACCGGGAATCAATATAGGTGCGTGGCGTGTCCGCAATGCGACCAGCTGGCAGCGGAGTAGTC
AACTGTCGGGGAAGTGGCAGGCAGCATATACCTATGCTGAGCGTGGACTGTACTCACTAAAAAGTCGTCTGACTCTGGGG
CAAAAGACTTCGCAGGGGGAGATATTTGATAGTGTGCCATTTACCGGTGTGATGTTGGCATCGGATGACAACATGGTGCC
CTACAGTGAGCGGCAGTTTGCTCCGGTAGTGCGTGGGATTGCCCGCACGCAGGCTCGGGTGGAGGTCAAACAGAATGGTT
ACACCATTTACAACACCACCGTGGCGCCCGGACCGTTTGCACTGCGGGATCTGTCGGTAACAGACAGTAGTGGTGATCTG
CATGTCACCGTGTGGGAGGCCGATGGCAGTACACAAATGTTTGTGGTGCCGTATCAGACCCCGGCGATAGCACTGCACCA
GGGATATTTGAAGTACAGCCTGTTGGCGGGCCGATACCGATCGTCAGACTCTGCAACGGATAAGGCGCAGATCGCGCAGG
CTACGTTGATGTATGGTCTGCCGTGGAATCTCACTGCATATGGCGGTATACAGAGTGCAACGCACTATCAAGCTGCATCG
CTTGGTTTGGGGGCATCTCTCGGGCGGTGGGGGAGTTTATCTGTCGATGGAAGCGACACACACAGTCAGCGTCAGGGGGA
AGCGGTACAGCAAGGAGCCTCCTGGCGACTGCGTTACAGCAACCAGCTGACTGCGACGGGAACAAATTTTTCTCTGACGA
GATGGCAGTATGCCTCGCAGGGCTATAACACCCTATCCGATGTGCTCGACAGTTATCGACATGATGGCAACCGTCTATGG
TCGTGGCGGGAAAATTTGCAGCCGAGCTCGCGTACCATCCTGATGTTGAGTCAGTCATGGGGGAGGCATTTGGGCAATCT
GAGTTTAACCGGTTCCCGTACCGACTGGCGTAATCGCCCCGGTCATGATGACAGCTACGGACTGAGTTGGGGAACCTCTA
TTGGAGGGGGCTCGCTGTCATTGAACTGGAATCAAAACAGAACGTTGTGGCGCAATGGCGCGCACAGTAAAGAGAACATA
ACCAGCCTGTGGTTCAGTATGTCATTAAGCCGCTGGACGGGGAATAATGTAAGTGCCAGTTGGCAGATGACTTCACCATC
ACACGGTGGTCAGATGCAACAAGTGGGGGGCAACGGAGAGGCATTCAGTCAGCAACTGGATTGGGAGGTGCGTCAGAGTT
ACCGTGCCGATGCCCCGCCAGGTGGTGGTAATAACAGCGCATTGCACTTGGCATGGAATGGGGGTTACGGCCTGTTAGGT
GGTGACTATAGCTACAGCCGGGCGATGCGCCAGATGGGAGTCAATATCGCGGGAGGTATAGTTATCCACCATCATGGTGT
GACGCTGGGGCAACCTTTGCAAGGCTCAGTGGCGCTGGTTGAAGCGCCAGGGGCCTCGGGGGTGCCAGTTGGCGGCTGGC
CTGGCGTTAAGACGGATTTTCGTGGCGACACCACAGTGGGCAACCTGAACGTCTATCAGGAGAATACAGTCAGCCTCGAT
CCGTCGCGACTACCGGATGACGCAGAGGTCACACAAACCGATGTGCGCGTGGTGCCAACCGAAGGGGCGGTGGTGGAAGC
GAAGTTTCACACTCGCATCGGGGCCAGGGCACTGATGACGCTGAAACGGGAAGATGGTAGCGCCATTCCTTTCGGGGCGC
AGGTTACAGTCAATGGACAGGATGGCAGTGCTGCTCTGGTGGATACTGATAGCCAGGTTTATCTCACTGGTCTGGCGGAT
AAGGGCGAACTGACGGTGAAATGGGGAGCACAGCAATGTCGGGTTAACTACCAGCTACCTGCCCACAAGGGAATCGCGGG
CTTGTATCAAATGAGCGGTCTCTGCAGATAG

Protein sequence :
MKFKQPALLLFIAGVVHCANAHAYTFDASMLGDAAKGVDMSLFNQGVQQPGTYRVDVMVNGKRVDTRDVVFKLEKDGQGT
PFLASCLTVSQLSRYGVKTEDYPQLWKAAKPPDECADLTAIPQAKAVLDINNQQLQLSIPQLALRPEFKGIAPEDIWDDG
IPAFLMNYSARTTQTDYKMDMERRDNSSWVQLQPGINIGAWRVRNATSWQRSSQLSGKWQAAYTYAERGLYSLKSRLTLG
QKTSQGEIFDSVPFTGVMLASDDNMVPYSERQFAPVVRGIARTQARVEVKQNGYTIYNTTVAPGPFALRDLSVTDSSGDL
HVTVWEADGSTQMFVVPYQTPAIALHQGYLKYSLLAGRYRSSDSATDKAQIAQATLMYGLPWNLTAYGGIQSATHYQAAS
LGLGASLGRWGSLSVDGSDTHSQRQGEAVQQGASWRLRYSNQLTATGTNFSLTRWQYASQGYNTLSDVLDSYRHDGNRLW
SWRENLQPSSRTILMLSQSWGRHLGNLSLTGSRTDWRNRPGHDDSYGLSWGTSIGGGSLSLNWNQNRTLWRNGAHSKENI
TSLWFSMSLSRWTGNNVSASWQMTSPSHGGQMQQVGGNGEAFSQQLDWEVRQSYRADAPPGGGNNSALHLAWNGGYGLLG
GDYSYSRAMRQMGVNIAGGIVIHHHGVTLGQPLQGSVALVEAPGASGVPVGGWPGVKTDFRGDTTVGNLNVYQENTVSLD
PSRLPDDAEVTQTDVRVVPTEGAVVEAKFHTRIGARALMTLKREDGSAIPFGAQVTVNGQDGSAALVDTDSQVYLTGLAD
KGELTVKWGAQQCRVNYQLPAHKGIAGLYQMSGLCR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
safC NP_454907.1 outer-membrane fimbrial usher protein Not tested SPI-6 Protein 0.0 98
afaC AAD44022.2 AfaC Virulence PAI-I AL862 Protein 0.0 50
afaC ADD91743.1 putative AfaC-VIII usher protein Not tested PAI-I AL862 Protein 0.0 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
safC YP_151652.1 outer-membrane fimbrial usher protein VFG0944 Protein 0.0 50
safC YP_151652.1 outer-membrane fimbrial usher protein VFG0853 Protein 0.0 49
safC YP_151652.1 outer-membrane fimbrial usher protein VFG0849 Protein 1e-172 45
safC YP_151652.1 outer-membrane fimbrial usher protein VFG0857 Protein 1e-173 45
safC YP_151652.1 outer-membrane fimbrial usher protein VFG0419 Protein 5e-169 44