Gene Information

Name : safC (t2558)
Accession : NP_806279.1
Strain : Salmonella enterica Ty2
Genome accession: NC_004631
Putative virulence/resistance : Virulence
Product : outer-membrane fimbrial usher protein
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 2634970 - 2637480 bp
Length : 2511 bp
Strand : -
Note : corresponds to STY0336 from Accession AL513382: Salmonella typhi CT18

DNA sequence :
ATGAAGTTCAAACAACCTGCCTTGCTACTGTTTATCGCGGGAGTGGTTCACTGCGCAAATGCGCACACTTACACATTCGA
TGCATCAATGTTGGGCGATGCAGCGAAAGGGGTTGATATGTCGCTCTTTAACCAGGGGGTACAACAGCCAGGGACTTATC
GAGTGGACGTAATGGTGAATGGTAAACGTGTCGACACCCGTGATGTGGTGTTCAAATTAGAAAAGGATGGGCAAGGAACG
CCTTTTCTGGCTTCTTGTTTGACGGTCAGTCAGCTTTCACGCTACGGCGTAAAAACGGAAGATTACCCTCAGTTGTGGAA
AGCAGCAAAGACCCCAGATGAGTGTGCGGATCTGACCGCCATTCCACAGGCTAAAGCGGTACTGGATATCAATAATCAGC
AACTGCAACTGAGTATTCCGCAGTTGGCGTTGCGTCCGGAATTTAAGGGGATCGCTCCAGAAGATCTTTGGGATGATGGT
ATTCCGGCGTTTCTGATGAACTACAGTGCGAGGACAACGCAGACGGATTACAAAATGGATATGGTGGGGCGTGACAACTC
TTCCTGGGTACAACTGCAACCGGGAATCAATATAGGTGCGTGGCGTGTCCGCAATGCGACCAGCTGGCAGCGGAGTAGTC
AACTGTCGGGGAAGTGGCAGGCAGCATATACCTATGCTGAGCGTGGACTGTACTCACTAAAAAGTCGTCTGACTCTGGGG
CAAAAGACTTCGCAGGGGGAGATATTTGATAGTGTGCCATTTACCGGTGTGATGTTGGCATCGGATGACAACATGGTGCC
CTACAGTGAGCGGCAGTTTGCTCCGGTAGTGCGTGGGATTGCCCGCACGCAGGCTCGGGTGGAGGTCAAACAGAATGGTT
ACACCATTTACAACACCACCGTGGCGCCCGGACCGTTTGCACTGCGGGATCTGTCGGTAACAGACAGTAGTGGTGATCTG
CATGTCACCGTGTGGGAGGCCGATGGCAGTACACAAATGTTTGTGGTGCCGTATCAGACCCCGGCGATAGCACTGCACCA
GGGATATTTGAAGTACAGCCTGTTGGCGGGCCGATACCGATCGTCAGACTCTGCAACGGATAAGGCGCAGATCGCGCAGG
CTACGTTGATGTATGGTCTGCCGTGGAATCTCACTGCATATGGCGGTATACAGAGTGCAACGCACTATCAAGCTGCATCG
CTTGGTTTGGGAGGATCTCTCGGGCGGTGGGGGAGTTTATCTGTCGATGGAAGCGACACACACAGTCAGCGTCAGGGGGA
AGCGGTACAGCAAGGAGCCTCCTGGCGACTGCGTTACAGCAACCAGCTGACTGCGACGGGGACAAATTTGTTTCTGACGA
GATGGCAATATGCCTCGCAGGGCTATAACACCCTATCCGATGTGCTCGACAGTTATCGACATAATGGCAACCGTCTATGG
TCGTGGCGGGAAAATTTGCAGCCGAGCTCACGTACCACCCTGATGTTGAGTCAGTCATGGGGGAGGCATTTGGGCAATCT
GAGTTTAATCGGTTCCCGTACCGACTGGCGTAATCGCCCCGGTCATGATGACAGCTACGGACTGAGTTGGGGAACCTCTA
TCGGAGGGGGCTCGCTGTCATTGAACTGGAATCAAAACAGAACGCTGTGGCGCAATGGCGGGCACCGTAAAGAGAACATA
ACCAGCCTGTGGTTCAGTATGCCATTAAGCCGCTGGACGGGGAATAATGTAAGTGCTAGTTGGCAGATGACTTCACCATC
ACACGGTGGTCAGACGCAACAAGTGGGGGTCAACGGAGAGGCATTCAGTCAGCAACTGGATTGGGAGGTGCGTCAGAGTT
ACCGTGCCGATGCCCCGCCAGGTGGTGGTAATAACAGCGCATTGCACTTGGCATGGAATGGGGCTTACGGCCTGTTAGGT
GGTGACTATAGCTACAGCCGGGCGATGCGCCAGATGGGAGTCAATATCGCGGGAGGTATAGTTATCCACCATCATGGTGT
GACGCTGGGGCAACCTTTGCAAGGCTCAGTGGCGCTGGTTGAAGCGCCAGGGGCCTCGGGGGTGCCAGTTGGCCCCTGGC
CTGGCGTTAAGACGGATTTTCGTGGCGACACCACAGTGGGCAACCTGAGCGTCTATCAGGAGAATACAGTCAGCCTCGAT
CCGTCGCAACTACCGGATGACGCAGAGGTCACACAAACCGATGTGCGCGTGGTGCCAACCGAAGGGGCGGTGGTGGAAGC
GAAGTTTCACACTCGCATCGGGGCCAGGGCACTGATGACGCTGAAACGGGAAGATGGTAGCGCCATTCCTTTCGGGGCGC
AGGTTATAGTCAATGGGCAGGATGGCAGCGCTGATCTGGTGGATACTGATAGCCAGGTTTATCTCACTGGTCTGGCGGAT
AAGGGCGAACTGACGGTGAAATGGGGAGCACAGCAATGTCGGGTTAACTACCACCTACCTGCCCACAAGGGAATCGCGGG
CTTGTATCAAATGAGCGGTCTCTGCAGATAG

Protein sequence :
MKFKQPALLLFIAGVVHCANAHTYTFDASMLGDAAKGVDMSLFNQGVQQPGTYRVDVMVNGKRVDTRDVVFKLEKDGQGT
PFLASCLTVSQLSRYGVKTEDYPQLWKAAKTPDECADLTAIPQAKAVLDINNQQLQLSIPQLALRPEFKGIAPEDLWDDG
IPAFLMNYSARTTQTDYKMDMVGRDNSSWVQLQPGINIGAWRVRNATSWQRSSQLSGKWQAAYTYAERGLYSLKSRLTLG
QKTSQGEIFDSVPFTGVMLASDDNMVPYSERQFAPVVRGIARTQARVEVKQNGYTIYNTTVAPGPFALRDLSVTDSSGDL
HVTVWEADGSTQMFVVPYQTPAIALHQGYLKYSLLAGRYRSSDSATDKAQIAQATLMYGLPWNLTAYGGIQSATHYQAAS
LGLGGSLGRWGSLSVDGSDTHSQRQGEAVQQGASWRLRYSNQLTATGTNLFLTRWQYASQGYNTLSDVLDSYRHNGNRLW
SWRENLQPSSRTTLMLSQSWGRHLGNLSLIGSRTDWRNRPGHDDSYGLSWGTSIGGGSLSLNWNQNRTLWRNGGHRKENI
TSLWFSMPLSRWTGNNVSASWQMTSPSHGGQTQQVGVNGEAFSQQLDWEVRQSYRADAPPGGGNNSALHLAWNGAYGLLG
GDYSYSRAMRQMGVNIAGGIVIHHHGVTLGQPLQGSVALVEAPGASGVPVGPWPGVKTDFRGDTTVGNLSVYQENTVSLD
PSQLPDDAEVTQTDVRVVPTEGAVVEAKFHTRIGARALMTLKREDGSAIPFGAQVIVNGQDGSADLVDTDSQVYLTGLAD
KGELTVKWGAQQCRVNYHLPAHKGIAGLYQMSGLCR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
safC NP_454907.1 outer-membrane fimbrial usher protein Not tested SPI-6 Protein 0.0 100
afaC AAD44022.2 AfaC Virulence PAI-I AL862 Protein 0.0 50
afaC ADD91743.1 putative AfaC-VIII usher protein Not tested PAI-I AL862 Protein 0.0 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
safC NP_806279.1 outer-membrane fimbrial usher protein VFG0853 Protein 0.0 50
safC NP_806279.1 outer-membrane fimbrial usher protein VFG0944 Protein 0.0 50
safC NP_806279.1 outer-membrane fimbrial usher protein VFG0849 Protein 4e-178 46
safC NP_806279.1 outer-membrane fimbrial usher protein VFG0857 Protein 1e-173 45
safC NP_806279.1 outer-membrane fimbrial usher protein VFG0419 Protein 3e-169 44