Gene Information

Name : BP2303 (BP2303)
Accession : NP_880941.1
Strain : Bordetella pertussis Tohama I
Genome accession: NC_002929
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 2426476 - 2427969 bp
Length : 1494 bp
Strand : +
Note : Similar to many eg. Pseudomonas aeruginosa probable aldehyde dehydrogenase Pa0219 TR:Q9I6R9 (EMBL:AE004460) (496 aa) fasta scores: E(): 1e-116, 60.97% id in 492 aa, and to Homo sapiens aldehyde dehydrogenase 1a2 AldH1a2 or raldh2 SW:DHA2_HUMAN (O94788) (4

DNA sequence :
ATGAGCACCCTGCCCCCGCTGTCCCATTGGGAATCCCTCGCCGCCGGCCTGACGCTGCGCAACCAGGCCTTCATCGACGG
CCGCTGGCACGATGGCCAGGCCGGGCCGCTGGCCGCCATCAACCCGGCCACCGGCCAGTTGCTCGCCGAAGTGACGGCCT
GCTCGCAAGCCGATATCGACCAGGCCGTCGCGGCCGCGCGGCGCGCCTTCGAGTCCGGCGTGTGGTCGCGCATGCCGCGC
CGCGAGCGCAAGCAATGCATGCTGCGCCTGGCCGCGCTGATCCGCGAGCACGCCGAAGAACTGGCCCTGATCGAAACGCT
GAACATGGGCAAGCCTATCGGCGACACCATGGCCTTCGACATCCCGGAAACCGCGCATACCTACGCGTGGTATGCCGAGA
CCATCGACAAGCAGTACGACGAAATCGCCCCCACCGACGCCGACGCGCTGGCCACCATCACGCGCGAACCGCTGGGCGTG
GTGGCCGCCGTGGTGCCATGGAACTACCCGCTGCTGATGGCCTCGTGGAAGGTGGCGCCGGCGCTGGCCGCCGGCAACAG
CGTGATCCTCAAGCCGGCCGAGCAGTCCTCGCTGTCGGCCCTGCGGCTGGCCGAACTGGCGCTCCAGGCCGGCATCCCCG
CCGGCGTGCTCAACGTGGTGCCGGGCGCCGGCCCGGTGGCCGGGCGCGCGCTCGGACTGCACATGGACGTGGATTGCCTG
GCCTTCACCGGCTCGACCGCCACCGGCAAGCGCTTCATGGAGTATTCCGGGCAATCCAACCTCAAGCAGGTCTGGCTGGA
ATGCGGCGGCAAGTCGCCGCACATCATTTTCGACGACTGCCCCGACCTGGACCGCGCCGCCCTGGCGGCGGCCATCGGCA
TCTTCAACAACCAGGGCGAGGTCTGCATCGCGGGCTCGCGCCTGTATGTGCAGGCCGGCATCTACGACACCTTCGTCAGC
AAGGTGGAGGCGTGTGCGCGCGCGATGCAGCCGGGCAATCCGCTCGACCCGGCCTCGCCGATGGGCGCCATGGTCGATGA
GAGGCAGATGGCGCGCGTGCTGGAATATGTCGAAAGCGGCCGGCGCGAAGGCGCGCGGCTGCGCATGGGCGGCGAGCGCG
TGCGCGCCGACAGCGGCGGCTACTACATAGAACCCACCATCTTCGAATGCGCGCGGCCCGACCTGACCATCGTGCGCGAG
GAGATCTTCGGCCCCGTGCTGGCGGTCACCCGGTTCGACGGCGAAGACGAGGTGGTGGCGCAGGCCAATGCCTCCGCCTA
TGGCCTGGGATCGGGCCTGTGGACGGCCGACCTGTCGCGCGCCCATCGCGTCTCGCGCAGGCTGCGCGCCGGCCTGGTAT
GGGTGAACTGCTACTTCGACGGCGACGTGACGGTGCCGTTCGGCGGCGTCAAGCAATCCGGCTTCGGGCGCGACAAGTCG
CTGCACGCGCTGGACAAGTACACCTCGCTGAAGACGACCTGGATCCGCCTGTAG

Protein sequence :
MSTLPPLSHWESLAAGLTLRNQAFIDGRWHDGQAGPLAAINPATGQLLAEVTACSQADIDQAVAAARRAFESGVWSRMPR
RERKQCMLRLAALIREHAEELALIETLNMGKPIGDTMAFDIPETAHTYAWYAETIDKQYDEIAPTDADALATITREPLGV
VAAVVPWNYPLLMASWKVAPALAAGNSVILKPAEQSSLSALRLAELALQAGIPAGVLNVVPGAGPVAGRALGLHMDVDCL
AFTGSTATGKRFMEYSGQSNLKQVWLECGGKSPHIIFDDCPDLDRAALAAAIGIFNNQGEVCIAGSRLYVQAGIYDTFVS
KVEACARAMQPGNPLDPASPMGAMVDERQMARVLEYVESGRREGARLRMGGERVRADSGGYYIEPTIFECARPDLTIVRE
EIFGPVLAVTRFDGEDEVVAQANASAYGLGSGLWTADLSRAHRVSRRLRAGLVWVNCYFDGDVTVPFGGVKQSGFGRDKS
LHALDKYTSLKTTWIRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 5e-115 55
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-72 42
hpaE AAO17179.1 HpaE Not tested tcd island Protein 3e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BP2303 NP_880941.1 aldehyde dehydrogenase VFG0082 Protein 3e-72 42