Gene Information

Name : invA (CV_2630)
Accession : NP_902300.1
Strain : Chromobacterium violaceum ATCC 12472
Genome accession: NC_005085
Putative virulence/resistance : Virulence
Product : invasion protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 2836202 - 2838262 bp
Length : 2061 bp
Strand : -
Note : identified by sequence similarity; ORF located using Blastx/COG1298/TC:3.A.6.1.1

DNA sequence :
CTGAACTCCCTGCTGAACGGCGCGCGATCGCGCCCGGAACTGCTGATCCTGCTGTTGATGGTGATGATCATCGCGATGCT
GATCATCCCGCTGCCCACCTACCTGGTGGACTTCCTGATCGGCCTGAACATCGTGCTGGCGGTGCTGGTGTTCATGGGCT
CGTTCTACATCGACCGCATCCTCAGCTTTTCCACCTTCCCGTCGGTGTTGCTGATCACCACGCTGTTCCGCCTGGCGCTG
TCCATCAGCACCAGCCGGCTGATCCTGATCGAGGCCGACGCCGGCGAGATCATCGCCACCTTCGGCCAGTTCGTGATCGG
CGACAGCCTGGCGGTGGGCTTCGTGGTGTTCTCCATCGTCACCGTGGTCCAGTTCATCGTGATCACCAAGGGGTCGGAGC
GGGTGGCCGAAGTGGCGGCGCGCTTCTCGCTGGACGGCATGCCCGGCAAGCAGATGAGCATCGACGCCGACCTCAAGGCC
GGCATCATCGACGCCGACGGCGCGCGCGAGCGCCGCAGCGTGCTGGAGCGCGAGAGCCAGCTGTACGGCTCCTTCGACGG
CGCGATGAAGTTCATCAAGGGCGACGCCATCGCCGGCATCATCATCATTTTCGTCAACTTCATCGGCGGCATCGCGGTGG
GCATGACCCAGCACGGCATGGACCTGTCCGCCGCCTTGTCCACCTACACGATGCTCACCATCGGCGACGGCCTGGTCGCG
CAGATCCCGGCGCTGCTGATCGCCATCAGCGCCGGCTTCATCGTCACCCGCGTCAACGGCGACAGCGACAACATGGGCCG
CAACATCATGAGCCAGCTGCTGGGCAATCCCTTCGTGCTGGTGGTGACCGCGGTGCTGGCGCTGGCGGTGGGCATGCTGC
CGGGCTTCCCGCTGATCGTGTTCCTGATCCTGGCCGCCGCGCTGGGCGGCCTGTTCTATTACAAGCGACGCGCCGCCGCC
GGCAAGCCCGCGCCGGGCATGCCGGCCCAGGCGGCCAAGGGCGGTTCGGCTCCGGGCGACGCGGCGAGGACGGGCGGGGC
GGACAGTTCGCTCGGCCTGATAGGCAATCTGGACAAGGTGGCGGCGGAAACCGTGCCGCTGATCTTGCTGGTGCCGGCCA
GCCGGCGCGCGGCGCTGGAGCAGGCGCAGCTGGCCGAGCGCCTGCGCAGCCAGTTTTTCATCGACTACGGCGTGCGGCTG
CCGGACATGCTGCTGCGCGAAGCCGAGGGCATGGACGACAACCGGGTGGCGGTGCTGATCAACGAGATCCGCGCCGATGA
ATTCCCGATCCGCTTCGACCTCGCGCGCGTGGTCAATCCCAGCGAGGAAATCCTGGCGCTGGACGTGCAGCCGGTGCTGG
AGCGCGAGTGCGTGTGGGTGAGGCCGGAGGACGGCGACCGGCTGGCCAAGCTGGGCTACCAGCTGCGCCCGGCGCTGGAC
GAGCTCTACCACTGCCTGGCGGCGCTGCTGGCCCGCCACGTCAACGAGTATTTCGGCGTCCAGGAAACCAAGCACATGCT
GGACCAGCTGGAGGGCAAGTACCCCGACCTGCTGAAGGAGGTGCTGCGCCATGCCACCGTGCAGCGCATCGCCGAAGTGC
TGCAGCGCCTGCTGGCGGAACGCATCTCGGTGCGCAACATGAAGCTGATCATGGAGGCGCTGGCGCTGTGGGCGCCGCGC
GAGAAAGACGTGATCAACCTGGTCGAACACGTCCGCGGCGCGCTGGCCCGCTACATCTGCCACAAATTCTCGGCCGGCGG
CGAGCTGCGGGCGGTGATGGTGTCGGCAGAAGTGGAGGACATGGTGCGCAAGGGCGTGCGCCAGACCTCGGCCGGCGCCT
TCCTCAACCTGGAGCCGGCGGCGTCCGACGAGCTGATGGACCTGTTCGCGCTGGGCCTGGAGGGCCTGGGCGTCGCCTAC
AAGGACATGGTGCTGCTCGCCTCGGTCGACGTGCGGCGCTTCATCAAGAAATTGGTCGAAACCCGCTTCCGCGAGCTGGA
AGTGGTGTCTTTCGGCGAAATCACCGACAGCGTGTCGGTCAATGTGATCAAAACTATCTGA

Protein sequence :
MNSLLNGARSRPELLILLLMVMIIAMLIIPLPTYLVDFLIGLNIVLAVLVFMGSFYIDRILSFSTFPSVLLITTLFRLAL
SISTSRLILIEADAGEIIATFGQFVIGDSLAVGFVVFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLKA
GIIDADGARERRSVLERESQLYGSFDGAMKFIKGDAIAGIIIIFVNFIGGIAVGMTQHGMDLSAALSTYTMLTIGDGLVA
QIPALLIAISAGFIVTRVNGDSDNMGRNIMSQLLGNPFVLVVTAVLALAVGMLPGFPLIVFLILAAALGGLFYYKRRAAA
GKPAPGMPAQAAKGGSAPGDAARTGGADSSLGLIGNLDKVAAETVPLILLVPASRRAALEQAQLAERLRSQFFIDYGVRL
PDMLLREAEGMDDNRVAVLINEIRADEFPIRFDLARVVNPSEEILALDVQPVLERECVWVRPEDGDRLAKLGYQLRPALD
ELYHCLAALLARHVNEYFGVQETKHMLDQLEGKYPDLLKEVLRHATVQRIAEVLQRLLAERISVRNMKLIMEALALWAPR
EKDVINLVEHVRGALARYICHKFSAGGELRAVMVSAEVEDMVRKGVRQTSAGAFLNLEPAASDELMDLFALGLEGLGVAY
KDMVLLASVDVRRFIKKLVETRFRELEVVSFGEITDSVSVNVIKTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 0.0 78
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 0.0 78
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 0.0 78
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 0.0 78
invA AAS66860.1 InvA Not tested SSR-2 Protein 6e-169 68
ECs3731 NP_311758.1 EivA Not tested LIM Protein 3e-172 65
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 9e-144 56
lssD AAO18050.1 LssD Virulence TTSS locus Protein 6e-101 44
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 8e-85 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
invA NP_902300.1 invasion protein VFG0557 Protein 0.0 78
invA NP_902300.1 invasion protein VFG1006 Protein 3e-172 66
invA NP_902300.1 invasion protein VFG2461 Protein 1e-147 61
invA NP_902300.1 invasion protein VFG1780 Protein 3e-143 54
invA NP_902300.1 invasion protein VFG0198 Protein 2e-99 45
invA NP_902300.1 invasion protein VFG0384 Protein 7e-100 44