Gene Information

Name : Thewi_2650 (Thewi_2650)
Accession : YP_004821258.1
Strain : Thermoanaerobacter wiegelii Rt8.B1
Genome accession: NC_015958
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2708457 - 2709152 bp
Length : 696 bp
Strand : -
Note : KEGG: tit:Thit_2312 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver re

DNA sequence :
ATGAGTTACAGAATACTGATAGTTGATGATGAGAAGCCCATAGTTGAGATAATCAAATACAATCTGGAAAAAGAGGGATA
CATAACTTATGAAGCTTATGATGGGGAAGAGGCTTTAAAAATAGCAAAAGAGCAAAATCCAGATTTGATAATACTTGATG
TGATGTTGCCTAAATTAGACGGTTTTTCAGTACTAAGGACTCTAAGGCAATCAATGACTATACCTATTTTGATGTTGACG
GCTAAAGAGGAAGAAGTAGACAAAGTATTGGGACTGGAATTGGGAGCTGATGACTACATAACGAAACCTTTTTCTATAAG
AGAACTCATAGCACGAGTAAAAGCTAATTTAAGGAGAATTAGTTTAAATGGAAACGAGTCTGGGAATATCATTTACGTAA
AAAATTTAAAAATTGACATGTCGAAATATAAAGTAGAAAAAAACAATAAAGAGATAGAACTTACCTCCAGAGAATTTGAA
CTTTTGAGATTTCTCATTTTAAACAAGGGGCTTATTTTTTCACGCGAAATGCTATTGGAAAAGGTATGGGGTTATGAATA
TCTGGGTGATATTAGAACGGTAGATGTCACCATAAGAAGACTGAGAGAAAAAATTGAAGATGACCCCAGTAACCCCAAGC
TTATTCACACAAAAAGAGGGGTTGGTTACTATTTTAGCGATGAGAAGCAGATTTAA

Protein sequence :
MSYRILIVDDEKPIVEIIKYNLEKEGYITYEAYDGEEALKIAKEQNPDLIILDVMLPKLDGFSVLRTLRQSMTIPILMLT
AKEEEVDKVLGLELGADDYITKPFSIRELIARVKANLRRISLNGNESGNIIYVKNLKIDMSKYKVEKNNKEIELTSREFE
LLRFLILNKGLIFSREMLLEKVWGYEYLGDIRTVDVTIRRLREKIEDDPSNPKLIHTKRGVGYYFSDEKQI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-37 43
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 4e-39 42
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 4e-39 42
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 4e-37 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_012469.1.7685629. Protein 5e-57 56
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_002952.2859905.p0 Protein 2e-51 54
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_007622.3794472.p0 Protein 2e-51 54
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_003923.1003749.p0 Protein 2e-51 54
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_007793.3914279.p0 Protein 3e-51 54
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_002951.3237708.p0 Protein 3e-51 54
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_013450.8614421.p0 Protein 3e-51 54
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_009782.5559369.p0 Protein 3e-51 54
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_009641.5332272.p0 Protein 3e-51 54
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_002745.1124361.p0 Protein 3e-51 54
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_002758.1121668.p0 Protein 3e-51 54
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator HE999704.1.gene2815. Protein 2e-48 49
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_012469.1.7686381. Protein 3e-44 48
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator AM180355.1.gene1830. Protein 7e-41 47
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_014475.1.orf0.gen Protein 2e-39 46
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_005054.2598277.p0 Protein 2e-39 46
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator DQ212986.1.gene4.p01 Protein 7e-41 46
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator AE000516.2.gene3505. Protein 2e-42 46
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_007793.3914065.p0 Protein 9e-36 45
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_007622.3794948.p0 Protein 9e-36 45
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_002951.3238224.p0 Protein 9e-36 45
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_002952.2859858.p0 Protein 9e-36 45
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_013450.8614146.p0 Protein 9e-36 45
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_010079.5776364.p0 Protein 9e-36 45
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_003923.1003417.p0 Protein 9e-36 45
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator NC_002758.1121390.p0 Protein 9e-36 45
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator AE016830.1.gene1681. Protein 6e-45 45
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator EU250284.1.orf4.gene Protein 2e-40 45
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator AF155139.2.orf0.gene Protein 5e-39 45
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator CP000675.2.gene1535. Protein 4e-38 44
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator HE999704.1.gene1528. Protein 1e-32 44
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator AE015929.1.gene1106. Protein 2e-28 43
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator AF162694.1.orf4.gene Protein 2e-38 43
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator BAC0308 Protein 2e-36 43
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator AF130997.1.orf0.gene Protein 2e-38 43
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator BAC0197 Protein 3e-38 43
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator BAC0125 Protein 2e-38 42
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator BAC0111 Protein 5e-35 42
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator FJ349556.1.orf0.gene Protein 2e-37 41
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator BAC0596 Protein 6e-32 41
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator CP001138.1.gene2239. Protein 6e-32 41
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator CP001918.1.gene3444. Protein 3e-30 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator VFG1389 Protein 5e-36 45
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator VFG0596 Protein 5e-38 43
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator VFG1563 Protein 2e-39 42
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator VFG1702 Protein 1e-39 42
Thewi_2650 YP_004821258.1 winged helix family two component transcriptional regulator VFG1386 Protein 5e-41 41