Gene Information

Name : YPTB0322 (YPTB0322)
Accession : YP_068868.1
Strain : Yersinia pseudotuberculosis IP 32953
Genome accession: NC_006155
Putative virulence/resistance : Virulence
Product : secretion system apparatus protein SsaV
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 387685 - 389733 bp
Length : 2049 bp
Strand : +
Note : with SsaC forms part of a protein export system across the inner and outer cell membranes; part of the Salmonella pathogenicity island 2; part of the type III secretion system

DNA sequence : 
ATGAGTAAGTCAGCACTGGTGCGGGGTTTGACGATGATCACCGCGCGGCAGGATATTTTTTTAGCGGTCATGTTGCTGGT
GGCGGTCTTTATGATGATCCTGCCACTGCCTACGACGATGGTGGATTTACTGATCGCCATCAATCTTGCCTTCTCCGTCA
TTCTCTTAATGATCTCGATCTATCTGCGCGATCCTTTGGAGTTCTCCGTCTTCCCGTCATTACTGTTGATCACCACCCTT
TATCGATTGGCACTGACGATCAGCACCACGCGACTGGTGCTGTTGCAACATGATGCCGGTGAGATTGTCGAGGCATTCGG
TCAGTTTGTCGTGGGCGGTAATCTGGCCGTCGGGATGATCATTTTTACCATTATCACGGTGGTCCAATTTATCGTGATTA
CCAAAGGTTCAGAGCGGGTTGCTGAGGTCAGTGCGCGCTTCTCACTTGATGGTATGCCGGGTAAGCAGATGAGCATCGAC
GGCGACATGCGTGCGGGTGCGATCGATTCGGTCGAAGCTAAACGGCTACGGGAGCGGGTACAAAAAGAGAGCCGCTTATT
TGGTGCTATGGACGGTGCCATGAAGTTTGTTAAAGGGGATGCCATCGCTGGGATCATTGTCATTCTGGTCAATATCATTG
GCGGTATCACTATTGGTGTGATGCAACACAAGATGTCCGCGGAAGAGGCGATGAATACCTACGCGGTATTATCGATAGGC
GATGGATTGTGCGCCCAAATCCCTTCATTACTGATCTCGATTACCGCCGGGATTATTGTTACCCGGGTTCCTGGCAGCAA
CAAACAGAGTCTGGCGAATGAGTTGGCGGTGCAGGTGGGGCGTCAACCGGATGCGCTGTGGTTAGCTGCCGCTATTCTGA
CGGTGTTCGCCCTGTTACCCGGCTTCCCGTTCCTGATCTTTATCACTTTGGCGGCCGCGGTTGCGGCTCCGGCTTTTTTA
CTTTATCGGAAGAACCGGCGGATATCGCAGGATGGTCGCGCAAATGGAGGCGGTGAAGAGGGGGCGGCCACGGGGCAGCG
TATGACGCCTGGTGCCGTACCGCTGATGCTGCACTGTGCATCAAATTTACATCACCCGCATTTAGGGCGCGATATTGATG
GCCTACGCTGGCGCTGGTTTGAGCATCTCGGTGTGCCATTGCCTGAGGTGGAGATCCGCTGTGATCCTACATTGGCAGAA
AATACCTTATCGGTGCAGGTGTATCAGGAGCGGGTGCTGGAGGTTGTGTTACCGCCCGACAGCTTGTTACTGACACGGCC
TTGCTCATCGTTAGTAACGAACAATCAGGCATTGGGCGCGAAGATGGGGTCATTTGATTGGCTGGATGCTAAACAGGCTA
TGCAAGCCAGAACCTTGGGTATCCCTTACGTGGAGGGGCATCAGCGGATCATCACCTGTCTGACCAGGGTGTTTGAACGG
TACACCGCCGAATTTATCGGCGTACAGGAGACTCGCTACCTGATGGATGCCATGGAAGGGCGCTATGGTGAGTTAGTGAA
AGAGCTACAACGGCAGATACCCGTCGGTAAAGTGGCTGAAATATTACAACGGCTGGTTGAGGAAAATATTTCCATTCGCG
ATTTACGGACTATTTTCGGCGCGTTGGTGGTTTGGGCACCGAAAGAAAAAGATATCGTGATGCTCACCGAATATGTCCGT
ATCGCCTTGCGCCGTCATTTGTGCCGTCGCTTTAGTCACAATAAAACCTGGATATCAGTATTACGCCTCGGTGATGGGGT
GGAGCATCTGATCCGCGACTCTATCCGCCAGACATCATCAGGCACTTACTCCGCACTGGAGGAGAGGCAATCCCTCTTGA
TCCTCAACAAAATAAAAAACGCATTTGCTGAAAACCAGGATGCGGTATTGCTTACCACCCTCGATGTTCGTCGCTTTGTC
CGCAAAATTATTGAGCGGGATCTCTTCGTGCTACCGGTACTTTCCTGGCAGGAACTGGGCGATGAAATGAATCTCAAGGT
GGCGGGCACCATTGAACTGATTGGCGATGAACTTGATGAAACTGCCTGA

Protein sequence : 
MSKSALVRGLTMITARQDIFLAVMLLVAVFMMILPLPTTMVDLLIAINLAFSVILLMISIYLRDPLEFSVFPSLLLITTL
YRLALTISTTRLVLLQHDAGEIVEAFGQFVVGGNLAVGMIIFTIITVVQFIVITKGSERVAEVSARFSLDGMPGKQMSID
GDMRAGAIDSVEAKRLRERVQKESRLFGAMDGAMKFVKGDAIAGIIVILVNIIGGITIGVMQHKMSAEEAMNTYAVLSIG
DGLCAQIPSLLISITAGIIVTRVPGSNKQSLANELAVQVGRQPDALWLAAAILTVFALLPGFPFLIFITLAAAVAAPAFL
LYRKNRRISQDGRANGGGEEGAATGQRMTPGAVPLMLHCASNLHHPHLGRDIDGLRWRWFEHLGVPLPEVEIRCDPTLAE
NTLSVQVYQERVLEVVLPPDSLLLTRPCSSLVTNNQALGAKMGSFDWLDAKQAMQARTLGIPYVEGHQRIITCLTRVFER
YTAEFIGVQETRYLMDAMEGRYGELVKELQRQIPVGKVAEILQRLVEENISIRDLRTIFGALVVWAPKEKDIVMLTEYVR
IALRRHLCRRFSHNKTWISVLRLGDGVEHLIRDSIRQTSSGTYSALEERQSLLILNKIKNAFAENQDAVLLTTLDVRRFV
RKIIERDLFVLPVLSWQELGDEMNLKVAGTIELIGDELDETA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0266 YP_002345347.1 secretion system apparatus protein SsaV Virulence Not named Protein 0.0 99
ssaV CAA70536.1 secretion system apparatus Virulence SPI-2 Protein 4e-159 58
ssaV NP_456114.1 putative type III secretion protein Virulence SPI-2 Protein 9e-159 58
ssaV NP_805085.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 9e-159 58
ssaV NP_460379.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 6e-159 58
ssaV YP_216422.1 secretion system apparatus protein SsaV Virulence SPI-2 Protein 6e-159 58
escV AAK26714.1 EscV Virulence LEE Protein 8e-125 49
escV YP_003236089.1 putative translocator EscV Virulence LEE Protein 7e-124 49
escV AAL57541.1 EscV Virulence LEE Protein 8e-125 49
escV YP_003223476.1 translocator EscV Virulence LEE Protein 2e-124 49
escV YP_003232152.1 T3SS structure protein EscV Virulence LEE Protein 1e-124 49
escV CAI43875.1 EscV protein Virulence LEE Protein 2e-124 49
escV CAC81861.1 EscV protein Virulence LEE II Protein 1e-124 49
escV AAC31514.1 L0035 Virulence LEE Protein 3e-123 49
escV ACU09459.1 EscV protein Virulence LEE Protein 3e-123 49
escV AAC38382.1 EscV Virulence LEE Protein 1e-123 49
escV NP_290269.1 hypothetical protein Virulence LEE Protein 4e-123 49
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 4e-123 49
escV AFO66414.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 2e-120 49
escV AFO66296.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 2e-120 49
unnamed AAL06368.1 EscV Virulence LEE Protein 2e-122 48
lssD AAO18050.1 LssD Virulence TTSS locus Protein 2e-121 46
invA AAS66860.1 InvA Not tested SSR-2 Protein 1e-85 42
hrcV AAT96193.1 HrcV Virulence T-PAI Protein 8e-89 41
hrcV AAT96139.1 HrcV Virulence T-PAI Protein 7e-89 41
hrcV ABA47273.1 HrcV Virulence S-PAI Protein 8e-87 41
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 4e-92 41
hrcV AAR25631.1 type III secretion protein HrcV Not tested Not named Protein 4e-81 41
hrcV AAB05999.2 HrcV Virulence Hrp PAI Protein 2e-91 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPTB0322 YP_068868.1 secretion system apparatus protein SsaV VFG0514 Protein 3e-159 58
YPTB0322 YP_068868.1 secretion system apparatus protein SsaV VFG0729 Protein 7e-124 49
YPTB0322 YP_068868.1 secretion system apparatus protein SsaV VFG0813 Protein 2e-123 49
YPTB0322 YP_068868.1 secretion system apparatus protein SsaV VFG0064 Protein 3e-126 48
YPTB0322 YP_068868.1 secretion system apparatus protein SsaV VFG0198 Protein 2e-104 45
YPTB0322 YP_068868.1 secretion system apparatus protein SsaV VFG0384 Protein 2e-117 45
YPTB0322 YP_068868.1 secretion system apparatus protein SsaV VFG2126 Protein 4e-95 42