Gene Information

Name : betB3 (pRALTA_0431)
Accession : YP_001796266.1
Strain :
Genome accession: NC_010529
Putative virulence/resistance : Virulence
Product : betaine aldehyde dehydrogenase, NAD-dependent
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 373312 - 374793 bp
Length : 1482 bp
Strand : -
Note : Evidence 2b : Function of strongly homologous gene; Product type e : enzyme

DNA sequence :
ATGAAACGCTATAAATTGTTCATCGACGGCCGTTACGTCGATCCAGTAAGACTGGAGTGGTTCGATACGGTCAACCCGTA
CACCGGCGAGGTATGGGCACGCATCCCTAGAGCTACAAAGGAAGACGTTGATATCGCGGTAGCGGCAGCTTCGCGTGCCC
TGAAGGCGGGACCTTGGGCGATGATGACAGCCACGGCGCGCGGCAAACTAATGCGACGTCTCGGTGATCTGGTCCTTGAA
AACGCCCAGCGCCTGGCAGAAACTGAGGTACGGGACAATGGCAAGGTGATGACTGAGGTGCTGAACCAGCTTCGGTCGCA
GTCGGAGTGGTGGTGGTACTTCAGCGGCCTAGCTGACAAGATAGAAGGCGCTGTTGTTCCTTTGGATAGGTCCGATGCCT
TTGCTTTTACGACCCACGAGCCAGTTGGCGTGGTCGGTGCCTTGACGGCCTGGAACTCGCCTTTGCTTTTCGTAGCGATG
AAATGCGCGCCCGCCTTGGCAGCAGGCTGCACCGTGGTCCTGAAGCCATCAGAATTTGCTTCGGCGAGCACACTGGAGTT
CATGGAGTTAACCCAGCACGCCGGCTTCCCGAGTGGAGTATTCAACGTTGTCACTGGATTTGGTCCGGAGACCGGGGCTG
CGTTGGTGGAACATCCTGACGTCGCCAAGGTGAGTTTTACTGGATCGGATGCCACCGGGGCAAAGGTATACGCGGCTGCT
GCAAAGTCTATGAAACGGGTTTCAATGGAATTAGGTGGCAAGTCGCCCAATATTGTGTTCGAAGACTGCGACTTCGCACA
GGCAGTAAGTGGAGTTGTGTCGGGGATCTTTGCAGCGACCGGTCAAGCTTGTGTGGCAGGGTCCCGCTTGCTGGTGCAGA
ATAGTATCAAGGACCTTTTCGTCGATCAACTTGTCAGCATGGTTGCATTGGCGCGAATCGGTGATCCAAACGCACCGGAG
AATAGCATCGGTCCTCTAGCAACACCGGAGCAGTATAAAAAGGTTTTGCGGTACATCGACATCGCCAAGTCAGAAGGTGC
TCGCTGTGTAATAGGAGGTGAGGCTATGCGGGATCTCTCTGGTGGGCAGTTTGTACAGCCCACCGTTTTTATCGACGTAA
AGAGCGACATGCGCATCGCGCAAGAAGAGGTATTCGGCCCCGTGCTCTCGGTCATGGGCTTCGATGACGAAGCGGACGCA
GTGAGGATCGCCAATGATGTTATTTATGGGCTCGCCGCCGGAGTATGGACAGCTGATATCTCCAAGGCGCTTCGTGTTTC
AAAGGCGCTCAGGGTCGGCACAGTGTGGATTAACGCCTATCGCGCGATGAGCTTCAACCTCCCTTTCGGTGGCATGAAGC
AATCCGGTATTGGCCGTGAGAACGGTATCGAAGCTGTGCGCGAGTTCCTCGAGACCAAAAGTGTCTGGGTTTCAACTAAG
GCAGGGACGCCGGCTAAGAAAGTCAGCGCAAATATGCAGTAG

Protein sequence :
MKRYKLFIDGRYVDPVRLEWFDTVNPYTGEVWARIPRATKEDVDIAVAAASRALKAGPWAMMTATARGKLMRRLGDLVLE
NAQRLAETEVRDNGKVMTEVLNQLRSQSEWWWYFSGLADKIEGAVVPLDRSDAFAFTTHEPVGVVGALTAWNSPLLFVAM
KCAPALAAGCTVVLKPSEFASASTLEFMELTQHAGFPSGVFNVVTGFGPETGAALVEHPDVAKVSFTGSDATGAKVYAAA
AKSMKRVSMELGGKSPNIVFEDCDFAQAVSGVVSGIFAATGQACVAGSRLLVQNSIKDLFVDQLVSMVALARIGDPNAPE
NSIGPLATPEQYKKVLRYIDIAKSEGARCVIGGEAMRDLSGGQFVQPTVFIDVKSDMRIAQEEVFGPVLSVMGFDDEADA
VRIANDVIYGLAAGVWTADISKALRVSKALRVGTVWINAYRAMSFNLPFGGMKQSGIGRENGIEAVREFLETKSVWVSTK
AGTPAKKVSANMQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-74 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-75 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-75 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-75 41
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-70 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-75 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
betB3 YP_001796266.1 betaine aldehyde dehydrogenase, NAD-dependent VFG0082 Protein 9e-75 41