PAI Gene Information


Name : ef0005
Accession : AAM75211.1
PAI name : Not named
PAI accession : AF454824
Strain : Enterococcus faecalis D32
Virulence or Resistance: Not determined
Product : EF0005
Function : -
Note : aggregation substance
Homologs in the searched genomes :   6 hits    ( 6 protein-level )  
Publication :
    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Modulation of virulence within a pathogenicity island in vancomycin-resistant Enterococcus faecalis", Nature 417 (6890), 746-750 (2002) PUBMED 12066186.

    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Direct Submission", Submitted (03-DEC-2001) Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, P.O. Box 26901, Oklahoma City, OK 73190, USA.


DNA sequence :
ATGAAAGCAAAAAAACAATATAAGACATATAAAGCTAAGAATCACTGGGTAACTGTCCCTATTCTTTTTCTAAGTGTGTT
AGGAGCCGTAGGATTAGCTACTGATAATGTACAAGCCGCGGAATTAGATACGCAACCAGAAACAACGACGGTTCAACCCA
ATAACCCCGACCTGCAGTCAGAAAAGGAAACACCTAAAACGGCAGTATCTGAAGAAGCAACAGTACAAAAAGACACTACT
TCTCAACCGACCAAAGTAGAAGAAGTAGCGCCAGAAAATAAAGGTACTGAACAAAGTTCAGCTACCCCAAATGATACCAC
AAACGCGCAACAACCAACAGTAGGAGCTGAAAAATCAGCACAAGAACAACCAGTAGTAAGCCCTGAAACAACCAATGAAC
CTCTAGGGCAGCCAACAGAAGTTGCACCAGCTGAAAATGAAGTGAATAAATCAACGTCCATTCCTAAAGAATTTGAAACA
CCAGACGTTGATAAAGCAGTTGATGAAGTAAAAAAAGATCCAAACATTACCGTTGTTGAAAAACCAGCAGAAGACTTAGG
CAACGTTTCTTCTAAAGATTTAGCTGCAAAAGAAAAAGAAGTAGACCAACTACAAAAAGAACAAGCGAAAAAGATTGCCC
AACAAGCAGCTGAATTAAAAGCCAAAAATGAAAAAATTGCCAAAGAAAATGCAGAAATTGCGGCAAAAAACAAAGCAGAA
AAAGAGCGTTATGAAAAAGAAGTCGCTGAATACAACAAGCATAAGAACGAAAACAGCTATGTCAATGAAGCGATTAGTAA
AAACCTAGTGTTCGATCAATCTGTCGTGACGAAAGACACTAAAATTTCGTCGATTAAAGGCGGAAAATTTATCAAAGCAA
CTGATTTTAATAAAGTAAATGCAGGGGATTCAAAAGATATCTTTACAAAATTACGGAAAGATATGGGCGGGAAAGTTACT
GGCAACTTCCAGAATTCCTTTGTAAAAGAGGCAAATCTTGGGTCTAATGGTGGGTATGCGGTTCTTTTAGAAAAAAATAA
ACCAGTGACAGTGACCTATACAGGACTAAACGCTAGTTATTTAGGACGTAAAATTACAAAAGCAGAATTTGTTTATGAAC
TACAATCCTCACCAAGCCAAAGTGGAACGTTAAATGCAGTATTTTCAAACGATCCGATTATCACGGCTTTTATTGGTACA
AACAGAGTCAATGGTAAGGATGTTAAAACACGCTTAACGATTAAGTTCTTTGATGCGTCAGGTAAAGAAGTACTACCAGA
TAAAGATAGTCCATTTGCGTATGCGCTGTCTTCTTTAAATTCAAGTTTAACGAATAAAGGTGGCCATGCGGAATTTGTTT
CTGATTTTGGGGCGAACAATGCGTTCAAATACATTAATGGTTCGTATGTGAAAAAACAAGCGGATGGAAAATTTTACTCA
CCGGAAGATATTGACTATGGCACAGGACCTTCTGGATTGAAAAATAGTGATTGGGACGCTGTAGGTCACAAGAATGCCTA
CTTTGGTTCAGGTGTAGGTCTAGCCAATGGGCGTATTTCCTTTTCTTTTGGTATGACAACAAAAGGAAAAAGTAATGTGC
CTGTATCTAGTGCGCAATGGTTTGCCTTTAGTACTAACTTAAATGCGCAATCAGTGAAGCCTATTTTCAATTATGGGAAT
CCAAAAGAACCAGAAAAAGCAACGATTGAATTCAATCGATACAAAGCCAATGTCGTTCCTGTACTTGTGCCAAATAAAGA
AGTCACTGATGGCCAGAAAAATGTCAATGATTTAAATGTGAAGCGTGGCGATTCTTTACAATACATTGTGACAGGGGATA
CGACAGAACTTGCCAAAGTAGATCCAAAAACAGTAACCAAACAAGGGATTCGAGATACCTTTGATGCAGAAAAAGTGACG
ATTGATTTATCCAAAGTGAAAGTTTATCAAGCAGACGCAAGTCTAAACGAGAAAGACTCAAAAGCTGTTGCTGCAGCAAT
TAATTCAGGAAGAGCTAAAGACGTGACTGCTTCTTATGATCTTCATTTAGATCAAAACACCGTCACAGCAATGATGAAAA
CCAACGCAGACGGTTCCATTGTTTTAGCAATGGGGTATAAATATTTACTTGTCTTGCCGTTTGTAGTGAAAAATGTGGAA
GGCGATTTTGAAAATACAGCTGTTCAGCTGACAAACGATGGTGAAACGGTAACAAATACAGTGATTAACCATGTGCCAGG
TAGTAATCCTTCCAAAGATGTAAAAGCAGATAAAAACGGTACAGTTGGCAGTGTTTCGCTACATGACAAAGATATTCCGT
TACAGACAAAAATTTATTATGAAGTGAAATCTTCCGAACGTCCAGCTAACTATGGCGGAATTACCAAAGAATGGGGCATG
AATGATGTCTTGGACACGACCCATGATCGTTTCACAGGGAAATGGCACGCTATTACGAATTATGACCTTAAAGTAGGGGA
TAAAACGTTAAAAGCAGGAACAGATATTTCTGCCTACATTCTTTTAGAAAACAAAGACAATAAAGACTTAACGTTTACGA
TGAATCAAGCACTATTGGCCGCCTTAAATGAAGGAAGCAATAAAGTAGGCAAACAAGCTTGGTCTGTGTATCTGGAAGTC
GAACGGATTAAAACAGGTGACGTAGAAAACACGCAAACAGAAAACTACAACAAAGAGCTGATGCGTTCTAATACCGTGGT
GACGCATACGCCTGATGATCCAAAACCAACCAAAGCCGTTCATAACAAGAAAGGGGAAGATATTAACCATGGAAAAGTTG
CTCGTGGTGATGTTCTTTCTTATGAAATGACCTGGGACTTAAAAGGGTACGATAAAGACTTTGCCTTTGATACAGTCGAT
CTTGCGACAGGCGTTTCTTTCTTCGATGATTACGATGAAACGAAGGTGACACCAATCAAAGACTTACTTCGTGTCAAAGA
TTCTAAAGGGGTAGACATTACGAACCAGTTCACGATCTCATGGGACGATGCCAAAGGCACGGTGACAATCTCTGCCAAAG
ACCCACAAGCCTTTATTCTAGCGCATGGTGGGCAAGAATTGCGTGTAACGCTCCCTACAAAAGTCAAAGCCGATGTTTCT
GGGGATATTTATAATTCAGCGGAACAAAATACATTTGGCCAACGAATTAAAACCAATACCGTTGTCAACCATATTCCAAA
AGTGAACCCTAAAAAAGACGTGGTTATTAAAGTCGGTGACAAACAAAGCCAAAATGGCGCCACAATCAAATTAGGGGAGA
AATTCTTCTATGAATTCACAAGTAGTGACATTCCTGCAGAATACGCTGGTGTTGTGGAAGAATGGTCGATTAGCGATAAA
CTAGACGTCAAACATGACAAATTTAGTGGCCAATGGTCTGTGTTTGCCAATTCTAATTTTGTTTTAGCAGACGGAACCAA
AGTGAATAAAGGGGACGACATTTCGAAACTATTCACGATGACCTTTGAACAAGGGGTAGTGAAAATCACGGCCAGTCAAG
CCTTTTTGGATGCGATGAATCTAAAAGAAAACAAAAACGTTGCGCACTCATGGAAAGCGTTCATTGGTGTAGAACGAATT
GCGGCAGGAGACGTTTACAACACGATTGAAGAATCTTTCAATAATGAAACGATCAAGACTAATACGGTAGTGACGCATAC
GCCAGAAAAACCACAAACACCACCAGAAAAAACAGTGATCGTGCCACCAACACCAAAAACACCACAAGCACCAGTAGAGC
CATTAGTGGTAGAAAAGGCAAGTGTAGAGCCAGAATTGCCACAAACAGGCGAAAAACAAAATGTCTTATTAACGGTAGCT
GGAAGTTTAGCTGCAATGCTTGGCTTAGCAGGCTTAGGCTTTAAACGTAGAAAAGAAACAAAATAA

Protein sequence :
MKAKKQYKTYKAKNHWVTVPILFLSVLGAVGLATDNVQAAELDTQPETTTVQPNNPDLQSEKETPKTAVSEEATVQKDTT
SQPTKVEEVAPENKGTEQSSATPNDTTNAQQPTVGAEKSAQEQPVVSPETTNEPLGQPTEVAPAENEVNKSTSIPKEFET
PDVDKAVDEVKKDPNITVVEKPAEDLGNVSSKDLAAKEKEVDQLQKEQAKKIAQQAAELKAKNEKIAKENAEIAAKNKAE
KERYEKEVAEYNKHKNENSYVNEAISKNLVFDQSVVTKDTKISSIKGGKFIKATDFNKVNAGDSKDIFTKLRKDMGGKVT
GNFQNSFVKEANLGSNGGYAVLLEKNKPVTVTYTGLNASYLGRKITKAEFVYELQSSPSQSGTLNAVFSNDPIITAFIGT
NRVNGKDVKTRLTIKFFDASGKEVLPDKDSPFAYALSSLNSSLTNKGGHAEFVSDFGANNAFKYINGSYVKKQADGKFYS
PEDIDYGTGPSGLKNSDWDAVGHKNAYFGSGVGLANGRISFSFGMTTKGKSNVPVSSAQWFAFSTNLNAQSVKPIFNYGN
PKEPEKATIEFNRYKANVVPVLVPNKEVTDGQKNVNDLNVKRGDSLQYIVTGDTTELAKVDPKTVTKQGIRDTFDAEKVT
IDLSKVKVYQADASLNEKDSKAVAAAINSGRAKDVTASYDLHLDQNTVTAMMKTNADGSIVLAMGYKYLLVLPFVVKNVE
GDFENTAVQLTNDGETVTNTVINHVPGSNPSKDVKADKNGTVGSVSLHDKDIPLQTKIYYEVKSSERPANYGGITKEWGM
NDVLDTTHDRFTGKWHAITNYDLKVGDKTLKAGTDISAYILLENKDNKDLTFTMNQALLAALNEGSNKVGKQAWSVYLEV
ERIKTGDVENTQTENYNKELMRSNTVVTHTPDDPKPTKAVHNKKGEDINHGKVARGDVLSYEMTWDLKGYDKDFAFDTVD
LATGVSFFDDYDETKVTPIKDLLRVKDSKGVDITNQFTISWDDAKGTVTISAKDPQAFILAHGGQELRVTLPTKVKADVS
GDIYNSAEQNTFGQRIKTNTVVNHIPKVNPKKDVVIKVGDKQSQNGATIKLGEKFFYEFTSSDIPAEYAGVVEEWSISDK
LDVKHDKFSGQWSVFANSNFVLADGTKVNKGDDISKLFTMTFEQGVVKITASQAFLDAMNLKENKNVAHSWKAFIGVERI
AAGDVYNTIEESFNNETIKTNTVVTHTPEKPQTPPEKTVIVPPTPKTPQAPVEPLVVEKASVEPELPQTGEKQNVLLTVA
GSLAAMLGLAGLGFKRRKETK