PAI Gene Information


Name : ef0037
Accession : AAM75243.1
PAI name : Not named
PAI accession : AF454824
Strain : Enterococcus faecalis D32
Virulence or Resistance: Not determined
Product : EF0037
Function : -
Note : putative ketopantoate reductase
Homologs in the searched genomes :   220 hits    ( 220 protein-level )  
Publication :
    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Modulation of virulence within a pathogenicity island in vancomycin-resistant Enterococcus faecalis", Nature 417 (6890), 746-750 (2002) PUBMED 12066186.

    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Direct Submission", Submitted (03-DEC-2001) Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, P.O. Box 26901, Oklahoma City, OK 73190, USA.


DNA sequence :
ATGAAAATTGCAATTGCAGGGGCCGGCGCGATGGGTTCCCGGTTCGGACTGATGTTGAAACAAGGTGGTAACGATGTTTT
GCTAATCGACGGCTGGCAGGAGCATATCAATGCCATCAAAGAAAACGGATTGAAGGCTAATTATAATGGCGAAGAAATTA
CTGTTAAAGTCTCAATTGTTAATCAGAATGAGGTGCCCACTGGTGAGCAATTTGATTTGATTATCTTATTCACGAAGGCA
ATGCAGTTGGAAAAAATGCTGCAGGATGTTAAACCATTAATTGCTGATCACACAGAAGTTTTGTGTCTTTTAAACGGTAT
CGGTCATGAAGACGTAATCGAAAAATTCGTACCGATGGAAAAAATCTTTATCGGCAACACCATGTGGACTGCTGGTCTAG
AAGGTCCCGGCAAGGCTAAATTATTTGGCAGCGGGTCTGTTGAATTGCAAAATCTAGGTATTGGCCAAGAAGAATCAGCG
AAAAAATTGGCGGAAACTTTGTCCGCGTCTGGTTTAAATGCCAAATATTCCGACAACATTCATTATTCAATTTATCGTAA
AGCTTGTGTCAATGGTACGATGAATGGCTTATGCACGATTTTAGACGTCAATATGGCGGGGCTTGGTGCAACCAAACCTG
CTCATGACATGGTAGTGACTATTGTTAACGAATTTGCAGCTGTTGCTGCCAAAGAAAACGTCAACTTAGACATTCCCGAA
GTAATCGAACATGTAGAAACTTGTTTTGACCCGACTACGATTGGTATGCATTTCCCATCGATGCACCAAGACTTGATAAA
AAATAACCGTTTGACCGAGATTGACTACATCAACGGAGCCATTTCTCGTAAAGGTAAAAAATATGGAGTAGTAACTCCTT
ACTGTGATTTCTTAACGCAACTGGTTCATAGTAAAGAAGAAATTCTAGGAGCGAAATAG

Protein sequence :
MKIAIAGAGAMGSRFGLMLKQGGNDVLLIDGWQEHINAIKENGLKANYNGEEITVKVSIVNQNEVPTGEQFDLIILFTKA
MQLEKMLQDVKPLIADHTEVLCLLNGIGHEDVIEKFVPMEKIFIGNTMWTAGLEGPGKAKLFGSGSVELQNLGIGQEESA
KKLAETLSASGLNAKYSDNIHYSIYRKACVNGTMNGLCTILDVNMAGLGATKPAHDMVVTIVNEFAAVAAKENVNLDIPE
VIEHVETCFDPTTIGMHFPSMHQDLIKNNRLTEIDYINGAISRKGKKYGVVTPYCDFLTQLVHSKEEILGAK