PAI Gene Information


Name : ef0056
Accession : AAM75261.1
PAI name : Not named
PAI accession : AF454824
Strain : Enterococcus faecalis D32
Virulence or Resistance: Virulence
Product : EF0056
Function : -
Note : Enterococcal surface protein; Esp
Homologs in the searched genomes :   2 hits    ( 2 protein-level )  
Publication :
    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Modulation of virulence within a pathogenicity island in vancomycin-resistant Enterococcus faecalis", Nature 417 (6890), 746-750 (2002) PUBMED 12066186.

    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Direct Submission", Submitted (03-DEC-2001) Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, P.O. Box 26901, Oklahoma City, OK 73190, USA.


DNA sequence :
TTGTTTGGAAAAAACAATAAGCATATGATTTTAAAAAAAGGGAGAAAAAGAGTATTAAAGTATAGCATAAAAAAATTAAG
TGTGGGTGTTGCATCAGTATTAGTTGGTGTAGGCCTTGTTTTTGGGGCAACTGGAATAGTTAATGCACAAATGGGTGAAG
GAAGATTAGCAAATTATTCTGCTTCAGGAAATACGTTTCAAGAAAATCCGGGATATACGAAGAATTATAATTTCTCGGAT
TTACAATTCAACCCTAAAGCAATAACTGGTGATGTGTTACAGGGAAATACAATTGATTTTGAGGTTTATGGGAAACATAA
TATTGCAGCTTCAACTGCAAACTGGGAAATTCGTCTTCAATTAGATGAACGATTGGCCCAGTATGTTGAAAAAATTCAAG
TTGATCCGAAGAAGGGCGTAGGAAATAGTAGACGAACTTTTGTAAGAATTAATGATTCGCTTGGCAGACCTACAAACATT
TGGAAGGTTAATTACATTCGAGCAAATGATGGACTATTTGCTGGGGCAGAAACAACTGATACACAAACTGCTCCTAACGG
TGTGATTACATTTGAAAAAAATTTAGATGAAATTTTTAAAGAAATTGGTGCAGATAATCTTAAAAGCGACCGTTTAATGT
ATCGTATCTATTTGGTAAGTCATCAAGATGACGATAAAATTGTACCTGGAATAGAAAGCACTGGTTACTTTTTGACAGAT
CAAGATGATTTCTATAATAAGTTAGATGTATCCGAAAATAATTCTGATCAATTTAAGCATGGATCGGTAAATACTAAATA
TGAAGAAGCTAATATCCAAACAAAAGACGGTTCTGGGTCTACTGGTGCTAATGGAGCTATAATTTTAGATCATAAGTTAA
CGAAAGAAAAGAATTTTTCTTATTCAACTTCTGCAAAGGGAACGCCTTGGTATGCTAACTACAAAATCGATGAACGTTTA
GTACCATATGTATCTGGAATACAAATGCATATGGTTCAGGCTGATAAAGTGGCATATAATGTTGCTTTTGAATCAGGAAA
AAAAGTGGCTGATTTAGCAATTGAGCGACGTGAAGGTCATGAGAATTATGGTATGGGTTCAATCACTGACAATGATTTAA
CTAAACTTATTGATTTTGCTAATGCTAGTCCACGACCTATCGTTGTTAGATATGTTTTACAACTGACTAAACCTTTAGAT
GAAATCTTAGAAGAAATGAAAGCAGCGGATAAAATCGAAGAAAATGCGCCATTTGGTGAAGATTTCATCTTTGATTCTTG
GTTGTCGGATACGAATAAAAAATTAATCCAGAACACTTATGGAACAGGTTATTATTATTTGCAAGATATTGATGGTGATG
GAAACCCTGACGATAAAGAAGAGAGCGGAGACACGAATCCATATATCGGGAAACCTGAATTAGAAGAAGTATATGATGTT
GACACAACAGTTAAGGGGAAAGTATTCATCCACGAGTTAGCGGGAACAGGTCACAAAGCGCAACTTGTTGATAAAGAAGG
TACTGTATTAGCAGAAAAAACTATCGCTCCAAATGAAAAAGATGGGGCTCCAATTTCAGATACTGTAGAATTTGAATTTA
CGGGTGTAGATTCAAGTAAACTAATCGCGAAAGATGAATTAAAAATCCAAATCGTTTCTCCAGGTTTTGATAAACCAGAA
GAAGGTTCAACCGTTATTAAGGAATCACCAAAAGCGGTTGATAAACAAACCGTGGTAGTTGGATTTAAACCAGATGCTAA
AGAATCAATTCGGAATAATAAAAACTTACCTGAAGATGCAGAGTATTCATGGAAAACAGAGCCTGATACTTCTAACGTTA
CTGATAGTACGAAAGGTATTGTAACTGTTAAGATAGGAAATCGAACTTTCGACGTGGATGTAGAGTTTGCTGTAAAAGCT
TCTCAAGCTATGGAAAATGATGCAACATACGTACCTATAACAACAACCCCAGAAACGACAATTCAAAGTGGTAAACCTAC
ATTTGATAAACCAGATGTTCCTCTAGCTAACGATGCCTTTTCAGTTTTAGATGTTTATAATAAGGACTTCGGCAATGCAA
GTGTTGACGCAAATACTGGTATTGTTACATTCACTCCAGCTAAAGGTGTAGGAGAATCGGAGCCGATTACTGGAACAATT
CCTATTAAAATTGTTTACCAAGATGGTTCTGTAGGCACGACCGATTTAGCAGTAACTGTAAGTAAAAATATTTATGAAAA
TCCAGGAGAAAACATTCCTGCAGGCTACCACAAAGTAACCTTCACCGCAGGAGAAGGAACAAGTATTGAAAGTGGAACAA
CAGTCTTTGCAGTGAAAGACGGCGTAAGCTTACCAGAAGATAAACTTCCGGTGTTGAAAGCAAAAGATGGTTATACAGAT
GCGAAATGGCCAGAAGAAGCAACGCAACCAATTAAAGCAGATGATACAGAATTTGTATCAAGTGCAACAAAATTGGATGA
TATCATTGAAAACCCAGGGGATAACATTCCTGCAGGCTACCACAAAGTAACCTTCACCGCAGGAGAAGGAACAAGTATTG
AAAGTGGAACAACAGTCTTTGCAGTGAAAGACGGCGTAAGCTTACCAGAAGATAAACTTCCGGTGTTGAAAGCAAAAGAT
GGTTATACAGATGCGAAATGGCCAGAAGAAGCAACGCAACCAATTAAAGCAGATGATACAGAATTTGTATCAAGTGCAAC
AAAATTGGATGATATCATTGAAAACCCAGGGGATAACATTCCTGCAGGCTACCACAAAGTAACCTTCACCGCAGGAGAAG
GAACAAGTATTGAAAGTGGAACAACAGTCTTTGCAGTGAAAGACGGCGTAAGCTTACCAGAAGATAAACTTCCGGTGTTG
AAAGCAAAAGATGGTTATACAGATGCGAAATGGCCAGGAGAAGCAACGCAACCAATTAAAGCAGATGATACAGAATTTGT
ATCAAGTGCAACAAAATTGGATGATAAATCTGATGCTGACAAATATACTCCTGAAGGTCAAAAAGTGACTACAGAATTGA
ATAAAGAACCTGACGCATCTGAGGGAATTAAAAATAAGAAAGATTTACCAAAAGATGCTAAGTATACTTGGAAAGAAAAA
GTAGATATTAGTACAGCTGGAAATAAAAAAGGTACGGTTGTAGTGACATATTCAGATGGATCATCTGATGAAGTTGAAGT
AGATGTCACAGTAACAGACAATCGCTCTGACGCTGATAAATATGAGCCAACAGTAGAAGGTGAAAAAGTAGAAATCGGTG
GTAAAGTAGATTTAACAGATAACGTTACTAACTTACCAACGTTACCACAAGGAACAACAGTAACAGATGTTACTCCTGGT
GGTACAATCGATACTAATACACCAGGTAATTACGAAGGTGTCATTGAAGTAACGTATCCAGATGGTACAAAAGATACAGT
AAAAGTTCCAGTAGAAGTAACAGACAATCGCTCTGACGCTGATAAATATGAGCCAACAGTAGAAGGTGAAAAAGTAGAAA
TCGGTGGTAAAGTAGATTTAACAGATAACGTTACTAACTTACCAACGTTACCACAAGGAACAACAGTAACAGATGTTACT
CCTGGTGGTACAATCGATACTAATACACCAGGTAATTACGAAGGTGTCATTGAAGTAACGTATCCAGATGGTACAAAAGA
TACAGTAAAAGTTCCAGTAGAAGTAACAGACAATCGCTCTGACGCTGATAAATATGAGCCAACAGTAGAAGGTGAAAAAG
TAGAAATCGGTGGTAAAGTAGATTTAACAGATAACGTTACTAACTTACCAACGTTACCACAAGGAACAACAGTAACAGAT
GTTACTCCTGGTGGTACAATCGATACTAATACACCAGGTAATTACGAAGGTGTCATTGAAGTAACGTATCCAGATGGTAC
AAAAGATACAGTAAAAGTTCCAGTAGAAGTAACAGACAATCGCTCTGATGCTGATAAATATACACCAATGGTAGAAGGTG
AAAAAGTAGAAATCGGTGGTAAAGTAGATTTAACAGATAACGTTACTAACTTACCAACGTTACCACAAGGAACAACAGTA
ACAGATGTTACTCCTGGTGGTACAATCGATACTAATACACCAGGTAATTACGAAGGTGTCATTGAAGTAACGTATCCAGA
TGGTACAAAAGATACAGTAAAAGTTCCAGTAGAAGTAACAGACAATCGCTCTGACGCTGATAAATATGAGCCAACAGTAG
AGGGTGAAAAAGTAGAAATTGGTGGTAAAGTAGATTTAACAGATAACGTTACTAACTTACCAACGTTACCACAAGGAACA
ACAGTAACAGATGTTACTCCTGGTGGTACAATCGATACTAATACACCAGGTAATTACGAAGGTGTCATTGAAGTAACGTA
TCCAGATGGTACAAAAGATACAGTAAAAGTTCCAGTAGAAGTAACAGACAATCGCTCTGACGCTGATAAATATGAGCCAA
CAGTAGAAGGTGAAAAAGTAGAAATCGGTGGTAAAGTGGATTTAACAGATAACGTTACTAACTTACCAACGTTACCACAA
GGAACAACAATAACAGATGTTACTCCTGGTGGTACAATCGATACTAATACACCAGGTAATTACGAAGGTGTCATTGAAGT
AACGTATCCAGATGGTACAAAAGATACAGTAAAAGTTCCAGTAGAAGTAACAGACAATCGCTCTGACGCTGATAAATATG
AGCCAACAGTAGAAGGTGAAAAAGTAGAAATCGGTGGTAAAGTGGATTTAACAGATAACGTTACTAACTTACCAACGTTA
CCACAAGGAACAACAATAACAGATGTTACTCCTGGTGGTACAATCGATACTAATACACCAGGTAATTACGAAGGTGTCAT
TGAAGTAACGTATCCAGATGGTACAAAAGATACAGTAAAAGTTCCAGTAGAAGTAACAGACAATCGCTCTGACGCTGATA
AATATACACCTAAAGGTCAAAAAGTAACTACTGAATTAAATAAAGAACCAGAAGCATCTGATGGAATTAAAAATAAATCG
GATCTACCAAAAGGAACTATGTATTTTTGGAAAGAAAAAGTAGATGTGGGTATACCTGGAAATAAAAAAGCTACTGTTGT
AGTAATATATCCAGATGGATCTAAAGAAGAGGTAGAGGTTGTTATTTCTGTAGTAGATAAAAAAGCGCCGAATAAACCTC
AAGTTGATCCTATTACAGATGGTGACAAAATTGTTACTGGTAAAACTGAACCAAATGCAGATGTAACAGTAACGTTACCT
GATGGAAGTCAATACCATGGCACAGCTGATAAGAGTGGTTACTTTAAAGTTAACGTTCCTAAATTAGAGGCAGGGACAAA
AGTAAAAGTAACTTCAACTGATGAATCTGGCAATACTAGTGAACCTACTGATGTAGTTGTTTCGTCAAATGAATTAAACG
GTGGAAAAGGTAATGGAACAGACAGTAAGACTAACAACAATCAAGATAAAAAACAATTCTTGAAAACTTATCCTAAAACA
GGAGAGGTTGATAGTAATATTTATACTATTGCTGGTGGTTTAATATTGTTAGGAACTTTAGGGTTATTAGGGTATGAAAA
ATGGAAAAAAGAGGATGAATAG

Protein sequence :
MFGKNNKHMILKKGRKRVLKYSIKKLSVGVASVLVGVGLVFGATGIVNAQMGEGRLANYSASGNTFQENPGYTKNYNFSD
LQFNPKAITGDVLQGNTIDFEVYGKHNIAASTANWEIRLQLDERLAQYVEKIQVDPKKGVGNSRRTFVRINDSLGRPTNI
WKVNYIRANDGLFAGAETTDTQTAPNGVITFEKNLDEIFKEIGADNLKSDRLMYRIYLVSHQDDDKIVPGIESTGYFLTD
QDDFYNKLDVSENNSDQFKHGSVNTKYEEANIQTKDGSGSTGANGAIILDHKLTKEKNFSYSTSAKGTPWYANYKIDERL
VPYVSGIQMHMVQADKVAYNVAFESGKKVADLAIERREGHENYGMGSITDNDLTKLIDFANASPRPIVVRYVLQLTKPLD
EILEEMKAADKIEENAPFGEDFIFDSWLSDTNKKLIQNTYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDV
DTTVKGKVFIHELAGTGHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSPGFDKPE
EGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSNVTDSTKGIVTVKIGNRTFDVDVEFAVKA
SQAMENDATYVPITTTPETTIQSGKPTFDKPDVPLANDAFSVLDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTI
PIKIVYQDGSVGTTDLAVTVSKNIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTD
AKWPEEATQPIKADDTEFVSSATKLDDIIENPGDNIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKD
GYTDAKWPEEATQPIKADDTEFVSSATKLDDIIENPGDNIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVL
KAKDGYTDAKWPGEATQPIKADDTEFVSSATKLDDKSDADKYTPEGQKVTTELNKEPDASEGIKNKKDLPKDAKYTWKEK
VDISTAGNKKGTVVVTYSDGSSDEVEVDVTVTDNRSDADKYEPTVEGEKVEIGGKVDLTDNVTNLPTLPQGTTVTDVTPG
GTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGKVDLTDNVTNLPTLPQGTTVTDVT
PGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGKVDLTDNVTNLPTLPQGTTVTD
VTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYTPMVEGEKVEIGGKVDLTDNVTNLPTLPQGTTV
TDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGKVDLTDNVTNLPTLPQGT
TVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGKVDLTDNVTNLPTLPQ
GTTITDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGKVDLTDNVTNLPTL
PQGTTITDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYTPKGQKVTTELNKEPEASDGIKNKS
DLPKGTMYFWKEKVDVGIPGNKKATVVVIYPDGSKEEVEVVISVVDKKAPNKPQVDPITDGDKIVTGKTEPNADVTVTLP
DGSQYHGTADKSGYFKVNVPKLEAGTKVKVTSTDESGNTSEPTDVVVSSNELNGGKGNGTDSKTNNNQDKKQFLKTYPKT
GEVDSNIYTIAGGLILLGTLGLLGYEKWKKEDE