PAI Gene Information


Name : ef0077
Accession : AAM75281.1
PAI name : Not named
PAI accession : AF454824
Strain : Enterococcus faecalis D32
Virulence or Resistance: Not determined
Product : EF0077
Function : -
Note : putative glycosyl hydrolase
Homologs in the searched genomes :   80 hits    ( 80 protein-level )  
Publication :
    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Modulation of virulence within a pathogenicity island in vancomycin-resistant Enterococcus faecalis", Nature 417 (6890), 746-750 (2002) PUBMED 12066186.

    -Shankar,N., Baghdayan,A.S. and Gilmore,M.S., "Direct Submission", Submitted (03-DEC-2001) Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, P.O. Box 26901, Oklahoma City, OK 73190, USA.


DNA sequence :
GTGATTGAAGTTACACCAAAATCTTTTTCGAGAACTTTTGATGATGAATTATTGATTGTAGAAGCTTGGGGTGAAAATGC
CGTTAGAGTCAGATCGTTTGTAGATATGAACTTTGAAAATAGACTTAATTCTTTAATTGGTGAGCCTGATGCTTTAGGTA
CAGTCATAATAAATCAAGACGAAAATAAGACAGAATTAATAAACGGGAAAATTAGAGTTGTGTTAGACCATCGGGACCGA
TTGACTTTTTATAATGAAAAAAATGAAGTGCTATTAAAAGAGTTTATCAGATTGAGAGCTGTCAAACATGATGACGGAAG
TGAAGATGCAGGTACAATTGAAATAACTAAAGATTTTAATTCAACGCTGAAGTTGAAGTCTAGAGAATACCACTCTAATT
TACAAGGTGGTTTTCAGGTTACAACTAGATTTGAATCTGAATCAAGTGAGAAGATTTTTGGAATGGGACAATATCAACAA
TCTTATCTTGATTTGAAGAATACAGTTCTAGAATTAGCTCAAAGAAACTCACAAGTATCTATACCATTCTATGTATCGAG
TTTAGGATATGGATTTTTATGGAATAATCCAGGTATAGGAGAGGTATCATTTGCTAAAAACATGACTCGATGGAAAATGG
CTTCTACTAATTATATTGACTATGTAGTAATTGCAGGTGATACCCCAAAAGAGATACTTCGAAATTATAGTGATTTAACT
GGTAAAGTTCCTAAAATGCCTGAAAACTTATTGGGATTATGGCAAAGTAAACTACGCTATCGATCTCCAAATGAAGTAAT
GGATGTTGTAAAAAAATACTATGCTTTGGGAATAAAACTTTCAACTATAGCTATTGACTATTTCCATTGGCCTAAACAAG
GTGAATATCGATTTGATGAAGAATATTGGCCTCAACCTGAACAATTTTTAAGAACATTAAGAGATGAATATAATGTAGAG
CCAATTATTTCCATATGGCCTACTGTACAAACTGATGCAATGAATTTTAATGAATATCTAGAAAATGGTTACTTAGTGAA
AGTAAATCGTGGCGTTAGATTAACAATGCAAATTCAAGGAAATACAATTTTTGTTGATATGACTAATGAGAAAGCACGAG
AATATGTTTGGAACCTCATTAAAAAGAATTATGTTAACAAAGGAGTTAAATATTTTTGGCTAGATGTAGCTGAGCCTGGG
TATTCTGTATATGATTTCGATAATTATCGATATAAAAAAGGAACCGATTTACAAATTGGGAATTTGTATCCAATCGATTA
TTTATCAATGATTTCTGAAGGTTTAGGAAATAATCAATCAGTTGTTACACTTGTAAGAGGTGGATGGGCAGGGGCACAAC
GCTATGGAGCTTTGTTATGGTCAGGAGATATTGATTCTAGCTTTGAAGCTTTTCGTAATCAAGTAAATACTGGATTAAAC
GTTGGGTTGGCTGGGTTACCTTGGTGGACAACAGATATTGGAGGATTTCATGGAGGAGATCCTAAAGATCCTGAGTTTAG
AGAATTACTAGTCCGCTGGTTCCAATATGCAACATTTTCGCCTATTTTACGAATGCATGGTGATCGCTTACCACACAGCA
AACCATTATCTGATCATGGAGGAGGATCAATGGTTACCGGAGCTCCAAATGAAATTTGGTCTTATGGTAAAGAAGTCGAA
CAAATACTAACGAAATATATAAAAATACGAGAAGAATTGAAGCCTTATATTAGTAAGTTGATGAGACAGGCCCATGAGTT
TGGTGATCCACTTATGAGAACATTATTTTATGAATATCCACATGATCAGAATGCTTGGAATATTGAAGATACCTATTTAT
TTGGAGATGCGATTCTTGTTGCGCCTATTGAAAATTATAAAGAGACTAGTCGAGAAGTTTATTTACCAAAAGGTGAAAGT
TGGACAAACCTATGGACAAGAGAAAACTTTGATGGTGGAAAAACAGTGGTAGTCGAAGCAGACATTCAACAAATCCCGAT
TTTTATCAAAACAAGTGAAAAAGGTAAATTTTCAAAATTATTTGATGTAATTAAGGAGGAAAATTAA

Protein sequence :
MIEVTPKSFSRTFDDELLIVEAWGENAVRVRSFVDMNFENRLNSLIGEPDALGTVIINQDENKTELINGKIRVVLDHRDR
LTFYNEKNEVLLKEFIRLRAVKHDDGSEDAGTIEITKDFNSTLKLKSREYHSNLQGGFQVTTRFESESSEKIFGMGQYQQ
SYLDLKNTVLELAQRNSQVSIPFYVSSLGYGFLWNNPGIGEVSFAKNMTRWKMASTNYIDYVVIAGDTPKEILRNYSDLT
GKVPKMPENLLGLWQSKLRYRSPNEVMDVVKKYYALGIKLSTIAIDYFHWPKQGEYRFDEEYWPQPEQFLRTLRDEYNVE
PIISIWPTVQTDAMNFNEYLENGYLVKVNRGVRLTMQIQGNTIFVDMTNEKAREYVWNLIKKNYVNKGVKYFWLDVAEPG
YSVYDFDNYRYKKGTDLQIGNLYPIDYLSMISEGLGNNQSVVTLVRGGWAGAQRYGALLWSGDIDSSFEAFRNQVNTGLN
VGLAGLPWWTTDIGGFHGGDPKDPEFRELLVRWFQYATFSPILRMHGDRLPHSKPLSDHGGGSMVTGAPNEIWSYGKEVE
QILTKYIKIREELKPYISKLMRQAHEFGDPLMRTLFYEYPHDQNAWNIEDTYLFGDAILVAPIENYKETSREVYLPKGES
WTNLWTRENFDGGKTVVVEADIQQIPIFIKTSEKGKFSKLFDVIKEEN