PAI Gene Information


Name : cag23 (HP0544)
Accession : AAR03967.1
PAI name : cag PAI
PAI accession : AY330644
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : Cag23
Function : -
Note : cagE; jhp0492; virB4-like protein
Homologs in the searched genomes :   43 hits    ( 43 protein-level )  
Publication :
    -Blomstergren,A., Lundin,A., Nilsson,C., Engstrand,L. and Lundeberg,J., "Comparative analysis of the complete cag pathogenicity island sequence in four Helicobacter pylori isolates", Gene 328, 85-93 (2004) PUBMED 15019987.

    -Blomstergren,A., Lundin,A., Nilsson,C., Engstrand,L. and Lundeberg,J., "Direct Submission", Submitted (26-JUN-2003) Biotechnology, Royal Institute of Technology, Alba Nova University Centre, Roslagstullsbacken 21, S-106 91 Stockholm, Sweden.


DNA sequence :
GTGTTTGTGGCAAGCAAACAAGCTGACGAACAAAAAAAGCTAATTATAGAGCAAGAGGTTCAAAAGCGGCAGTTTCAAAA
AATAGAAGAACTTAAAGCAGACATGCAAAAAGGTGTCAATCCCTTTTTTAAAGTCTTGTTTGATGGGGGGAATAGGTTGT
TTGGTTTCCCTGAAACTTTTATTTATTCCTCTATATTTATATTGTTTGTAACAATTGTATTATCTGTTATTCTTTTTCAA
GCCTATGAACCTGTTTTGATTGTAACGATTGTTATTGTGCTTGTAGCTCTTGGATTCAAGAAAGATTATAGGCTTTATCA
AAGAATGGAGCGAGCGATGAAATTTAAAAAACCTTTTTTGTTTAAGGGCGTGAAAAACAAAGCGTTCATGAGCATTTTTT
CCATGAAGCCTAGTAAAGAAATGGCTAATGACATCCACTTAAATCCAAACAGAGAAGACAGGCTTGTGAGCGCTGCAAAC
TCCTATCTAGCGAATAACTATGAATGTTTTTTAGATGATGGGGTGATCCTTACTAACAACTATTCTCTTTTAGGCACAAT
CAAATTGGGGGGCATTGATTTTTTAACCACTTCCAAAAAAGATCTCATAGAGTTACACGCTTCTATTTATAGCGTTTTTA
GGAATTTTGTTACCCCTGAATTCAAATTTTATTTTCACACTATTAAAAAGAAAATCGTTATTGATGAAACCAATAGGGAT
TATGGTCTTATTTTTTCTAATGATTTCATGCGAGCCTATAATGAGAAGCAAAAGAGAGAAAGTTTTTATGATATTAGTTT
TTATCTCACCATAGAGCAAGATTTATTAGACACTCTCAATGAACCCGTTATGAATAAAAAGCATTTTGCAGACAATAATT
TTGAAGAGTTTCAAAGGATTATTAGAGCCAAGCTTGAAAACTTCAAGGATAGGATAGAGCTCATAGAAGAGCTATTGAGT
AAATACCACCCCACCAGATTGAAAGAATACACCAAAGATGGCGTTATTTACTCCAAACAATGTGAGTTTTACAATTTTCT
TGTGGGAATGAATGAAGCCCCTTTTATTTGCAACAGAAAAGACTTGTATCTCAAAGAAAAAATGCATGGTGGGGTGAAAG
AAGTTTATTTTGCCAACAAGCATGGAAAAATCTTAAATGACGATTTGAGTGAAAAATATTTTAGCGCTATTGAGATTAGT
GAATACGCCCCTAAATCACAGAGCGATTTGTTTGATAAAATCAACGCCCTAGACAGCGAATTTATTTTCATGCATGCTTA
TTCGCCTAAAAACTCACAAGTTTTAAAGGACAAACTGGCTTTCACCTCTAGAAGAATTATTATTAGTGGAGGCTCCAAAG
AGCAAGGCATGACTTTGGGTTGTTTGAGCGAATTAGTGGGTAATGGTGATATTACGCTAGGCAGTTATGGTAATTCTTTA
GTGCTGTTTGCTGATAGCTTTGAAAAAATGAAACAAAGCGTTAAGGAATGCGTCTCGAGTCTTAACGCTAAAGGTTTTTT
AGCCAACGCAGCGACTTTCTCTATGGAAAATTACTTTTTTGCCAAACATTGCTCTTTTATCACGCTTCCTTTTATTTTTG
ATGTAACTTCTAATAATTTTGCTGATTTCATCGCTATGAGGGCTATGAGTTTTGATGGCAATCAAGAGAATAACGCTTGG
GGCAATAGTGTGATGACGCTAAAAAGCGAGATCAATTCGCCTTTTTATCTGAACTTCCACATGCCCACTGATTTTGGTTC
AGCTTCAGCAGGACACACTTTGATACTTGGCTCAACCGGTTCAGGTAAGACAGTGTTTATGTCAATGACCTTGAACGCTA
TGGGGCAATTTGTTCACAATTTTCCTGCTAATGTCAGCAAAGACAAACAAAAGCTCACTATGGTTTATATGGATAAAGAT
TATGGCGCTTATGGGAATATTGTCGCAATGGGTGGGGAGTATGTCAAGATTGAGCTAGGGACAGATACAGGATTAAATCC
TTTTGCTTGGGCGGCTTGTGTGCAAAAAACAAATGCAACAATGGAGCAAAAACAAACAGCTATTTCTGTTGTCAAAGAGC
TTGTGAAAAACTTAGCGACCAAAAGCGATGAAAAAGATGAAAATGGCAACAGCATCTCTTTTAGCCTAGCAGATTCTAAT
ACGCTTGCAGCGGCAGTAACCAACCTTATCACAGGAGATATGAACCTAGATTATCCCATCACTCAACTTATTAATGCTTT
CGGGAAAGACCACAATGATCCTAATGGGCTTGTCGCGCGATTAGCGCCTTTTTGCAAATCAACCAATGGTGAATTTCAAT
GGCTTTTTGATAATAAAGCAACGGATCGCTTAGATTTTTCAAAAACGATTATTGGCGTTGATGGGTCAAGTTTCTTAGAC
AATAATGATGTTTCGCCCTTTATTTGTTTTTACCTTTTCGCTCGTATCCAAGAGGCAATGGATGGGCGTAGATTTGTCTT
AGATATTGATGAAGCTTGGAAATATTTAGGCGATCCAAAGGTCGCTTATTTTGTAAGAGACATGCTAAAAACTGCAAGGA
AAAGAAACGCTATTGTCAGGCTTGCGACTCAAAGCATCACTGATCTTTTGGCTTGCCCCATTGCTGATACGATTAGAGAA
CAATGCCCTACAAAGATTTTTCTGAGAAACGATGGGGGCAATCTTTCTGATTACCAAAGATTGGCTAATGTTACAGAAAA
AGAATTTGAAATCATCACTAAGGGACTAGATAGGAAAATTCTCTACAAACAAGATGGAAGCCCTAGCGTTATCGCTAGTT
TTAATTTGAGAGGCATTCCTAAAGAATATTTGAAAATTTTATCCACAGATACTGTATTTGTCAAAGAAATTGACAAGATT
ATCCAAAACCATAGTATCATAGATAAATATCAGGCCTTGAGGCAAATGTATCAACAAATAGAGGAGTATTAA

Protein sequence :
MFVASKQADEQKKLIIEQEVQKRQFQKIEELKADMQKGVNPFFKVLFDGGNRLFGFPETFIYSSIFILFVTIVLSVILFQ
AYEPVLIVTIVIVLVALGFKKDYRLYQRMERAMKFKKPFLFKGVKNKAFMSIFSMKPSKEMANDIHLNPNREDRLVSAAN
SYLANNYECFLDDGVILTNNYSLLGTIKLGGIDFLTTSKKDLIELHASIYSVFRNFVTPEFKFYFHTIKKKIVIDETNRD
YGLIFSNDFMRAYNEKQKRESFYDISFYLTIEQDLLDTLNEPVMNKKHFADNNFEEFQRIIRAKLENFKDRIELIEELLS
KYHPTRLKEYTKDGVIYSKQCEFYNFLVGMNEAPFICNRKDLYLKEKMHGGVKEVYFANKHGKILNDDLSEKYFSAIEIS
EYAPKSQSDLFDKINALDSEFIFMHAYSPKNSQVLKDKLAFTSRRIIISGGSKEQGMTLGCLSELVGNGDITLGSYGNSL
VLFADSFEKMKQSVKECVSSLNAKGFLANAATFSMENYFFAKHCSFITLPFIFDVTSNNFADFIAMRAMSFDGNQENNAW
GNSVMTLKSEINSPFYLNFHMPTDFGSASAGHTLILGSTGSGKTVFMSMTLNAMGQFVHNFPANVSKDKQKLTMVYMDKD
YGAYGNIVAMGGEYVKIELGTDTGLNPFAWAACVQKTNATMEQKQTAISVVKELVKNLATKSDEKDENGNSISFSLADSN
TLAAAVTNLITGDMNLDYPITQLINAFGKDHNDPNGLVARLAPFCKSTNGEFQWLFDNKATDRLDFSKTIIGVDGSSFLD
NNDVSPFICFYLFARIQEAMDGRRFVLDIDEAWKYLGDPKVAYFVRDMLKTARKRNAIVRLATQSITDLLACPIADTIRE
QCPTKIFLRNDGGNLSDYQRLANVTEKEFEIITKGLDRKILYKQDGSPSVIASFNLRGIPKEYLKILSTDTVFVKEIDKI
IQNHSIIDKYQALRQMYQQIEEY