PAI Gene Information


Name : dfrA1
Accession : AAX48777.1
PAI name : SGI2
PAI accession : AY963803
Strain : Salmonella enterica RSK2980
Virulence or Resistance: Resistance
Product : DfrA1 trimethoprim-insensitive dihydrofolate reductase
Function : -
Note : -
Homologs in the searched genomes :   17 hits    ( 17 protein-level )  
Publication :
    -Levings,R.S., Djordjevic,S.P. and Hall,R.M., "SGI2, a relative of Salmonella genomic island SGI1 with an independent origin", Antimicrob. Agents Chemother. 52 (7), 2529-2537 (2008) PUBMED 18443113.

    -Levings,R.S., Djordjevic,S.P. and Hall,R.M., "Direct Submission", Submitted (12-SEP-2007) NSW Department of Primary Industries, Elizabeth Macarthur Agricultural Institute, Camden, NSW 2570, Australia REMARK Sequence update by submitter.

    -Levings,R.S., Djordjevic,S.P. and Hall,R.M., "Direct Submission", Submitted (08-JAN-2008) NSW Department of Primary Industries, Elizabeth Macarthur Agricultural Institute, Private Mail Bag 8, Camden, NSW 2570, Australia REMARK Sequence update by submitter.

    -Levings,R.S., Djordjevic,S.P. and Hall,R.M., "Direct Submission", Submitted (10-APR-2008) NSW Department of Primary Industries, Elizabeth Macarthur Agricultural Institute, Private Mail Bag 8, Camden, NSW 2570, Australia REMARK Sequence update by submitter.

    -Levings,R.S., Hall,R.M. and Djordjevic,S.P., "Direct Submission", Submitted (17-MAR-2005) Microbiology and Immunology Section, New South Wales Department of Primary Industries, Elizabeth Macarthur Agricultural Institute, Camden, NSW 2570, Australia.

    -Levings,R.S., Lightfoot,D., Partridge,S.R., Hall,R.M. and Djordjevic,S.P., "The genomic island SGI1, containing the multiple antibiotic resistance region of Salmonella enterica serovar Typhimurium DT104 or variants of it, is widely distributed in other S. enterica serovars", J. Bacteriol. 187 (13), 4401-4409 (2005) PUBMED 15968049.

    -Wilson,N.L. and Hall,R.M., "Unusual class 1 integron configuration found in Salmonella genomic island 2 from Salmonella enterica serovar Emek", Antimicrob. Agents Chemother. 54 (1), 513-516 (2010) PUBMED 19884375.

    -Wilson,N.L. and Hall,R.M., "Unusual Class 1 Integron Configuration found in SGI2 from Salmonella enterica Serovar Emek", Unpublished.

    -Wilson,N.L. and Hall,R.M., "Direct Submission", Submitted (12-MAY-2009) School of Molecular and Microbial Biosciences, The University of Sydney, Sydney, NSW 2006, Australia REMARK Sequence update by submitter.


DNA sequence :
GTGAAACTATCACTAATGGTAGCTATATCGAAGAATGGAGTTATCGGGAATGGCCCTGATATTCCATGGAGTGCCAAAGG
TGAACAGCTCCTGTTTAAAGCTATTACCTATAACCAATGGCTGTTGGTTGGACGCAAGACTTTTGAATCAATGGGAGCAT
TACCCAACCGAAAGTATGCGGTCGTAACACGTTCAAGTTTTACATCTGACAATGAGAACGTATTGATCTTTCCATCAATT
AAAGATGCTTTAACCAACCTAAAGAAAATAACGGATCATGTCATTGTTTCAGGTGGTGGGGAGATATACAAAAGCCTGAT
CGATCAAGTAGATACACTACATATATCTACAATAGACATCGAGCCGGAAGGTGATGTTTACTTTCCTGAAATCCCCAGCA
ATTTTAGGCCAGTTTTTACCCAAGACTTCGCCTCTAACATAAATTATAGTTACCAAATCTGGCAAAAGGGTTAA

Protein sequence :
MKLSLMVAISKNGVIGNGPDIPWSAKGEQLLFKAITYNQWLLVGRKTFESMGALPNRKYAVVTRSSFTSDNENVLIFPSI
KDALTNLKKITDHVIVSGGGEIYKSLIDQVDTLHISTIDIEPEGDVYFPEIPSNFRPVFTQDFASNINYSYQIWQKG