PAI Gene Information


Name : subA
Accession : AFX83959.1
PAI name : SE-PAI
PAI accession : JQ994271
Strain : Escherichia coli 042
Virulence or Resistance: Virulence
Product : subtilase cytotoxin subunit A
Function : -
Note : member of the subtilase-like serine protease family
Homologs in the searched genomes :   No hits  
Publication :
    -Michelacci,V., Tozzoli,R., Caprioli,A., Grande,L. and Morabito,S., "Direct Submission", Submitted (27-APR-2012) Veterinary Public Health and Food Safety, Istituto Superiore di Sanita, Viale Regina Elena 299, Rome, RM 00161, Italy.

    -Michelacci,V., Tozzoli,R., Caprioli,A., Martinez,R., Scheutz,F., Grande,L., Sanchez,S. and Morabito,S., "A new pathogenicity island carrying an allelic variant of the Subtilase cytotoxin is common among Shiga toxin producing Escherichia coli of human and ovine origin", Clin. Microbiol. Infect. 19 (3), E149-E156 (2013) PUBMED 23331629.


DNA sequence :
GTGCTGAAAAATTTACGGCTGCATATTCTGTTCCTGCTTTTTATCTCAGTGTCAGTCAGGGCGGAAAAACCATGGTATTT
TGATGCAATTGGTCTGACAGAAACAACCATGTCGCTCACAGACAAAAATACCCCGGTTGTCGTATCTGTTGTTGATTCCG
GAGTGGCATTTGTAGGAGGCCTCAGCGACAGCGAATTTGCCAAATTCAGTTTTACTCAGGATGGTTCGCCATTCCCGGTA
AAAGAGCCTGAAGCTTTATATATTCATGGTACTGCCATGGCTTCACTCATTGCCTCACGTCATGAGGTTTATGGTGTTTA
TCCTCATGCACTGATATCCAGCAGAAGGGTTATTCCTGACGGTGTACAGGACTCATGGATTAGAGCAACTGAAAGCATTA
TGTCAAATGTTTTTCTTGCACCAGGAGAAGAGAAAATCATTAATATATCGGGAGGCCAGAAGGGGATATCTTCCGCATCG
GTCTGGTCCGAACTGCTTTCCCGTATGGGCCGGAATAATGAGCGATTAATTGTTGCGGCAGTGGGTAATGATGGCGCAGA
TATACGAAAACTGAGTGCTCAGCAGAGAATATGGCCTGCGGCTTACCATCCGGTCAGCAGTGTGAATAAAAAGCAGGATC
CTGTGATAAGAGTGGCAGCTCTGGCACAGTACCGGAAAGGAGAAACACCTGTATTGCATGGTGGAGGGGTCACCGGAAGT
CGGTTCGGAAACGGCTGGGTTGATATTGCCGCACCGGGACAGAATATTACATTCCTCAAACCAGATGGAAAAACGGGGAT
CGGTAGTGGAACCTCGGAAGCAACAGCTATAGTTTCCGGCGTTCTGGCAGCGATGGTCTCATGTAATCCCCGTGCAACAG
CGACAGAACTGAAGCGTACACTGCTGGAGTCTGCAGACAAATACCCCTCACTTGCAGATAAGGTGACGGAAGGGAGAGTT
CTTAATGCAGAAAAAGCAATTAGCATGTTCTGCAAGAAAAATTATATTCCTGTCCGTCAGGGAAGGATGAGTGAAGAACT
GTAA

Protein sequence :
MLKNLRLHILFLLFISVSVRAEKPWYFDAIGLTETTMSLTDKNTPVVVSVVDSGVAFVGGLSDSEFAKFSFTQDGSPFPV
KEPEALYIHGTAMASLIASRHEVYGVYPHALISSRRVIPDGVQDSWIRATESIMSNVFLAPGEEKIINISGGQKGISSAS
VWSELLSRMGRNNERLIVAAVGNDGADIRKLSAQQRIWPAAYHPVSSVNKKQDPVIRVAALAQYRKGETPVLHGGGVTGS
RFGNGWVDIAAPGQNITFLKPDGKTGIGSGTSEATAIVSGVLAAMVSCNPRATATELKRTLLESADKYPSLADKVTEGRV
LNAEKAISMFCKKNYIPVRQGRMSEEL