PAI Gene Information


Name : HP0527
Accession : BAD13833.1
PAI name : cag PAI
PAI accession : AB120418
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cag pathogenicity island protein
Function : -
Note : similar to virB10, H.pylori 26695 gene HP0527:cag7, J99 gene JHP0476, NCTC11638 gene ORF13andORF14:cag-Y
Homologs in the searched genomes :   31 hits    ( 30 protein-level,   1 DNA-level )  
Publication :
    -Azuma,T., Yamakawa,A. and Yamazaki,S., "Direct Submission", Submitted (12-SEP-2003) Takeshi Azuma, University of Fukui Faculty of Medical Sciences, General Medicine Second Department of Internal Medicine; Shimoaizuki 23-3, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:8.

    -Azuma,T., Yamakawa,A., Yamazaki,S., Ohtani,M., Ito,Y., Muramatsu,A., Suto,H., Yamazaki,Y., Keida,Y., Higashi,H. and Hatakeyama,M., "Distinct diversity of the cag pathogenicity island among Helicobacter pylori strains in Japan", J. Clin. Microbiol. 42 (6), 2508-2517 (2004) PUBMED 15184428.


DNA sequence :
ATGAATGAAGAAAACGATAAACTTGAAACTTCTAAAAAAACCCAACAACATTCACCCCAAGATTTATCCAATGAAGAAGC
AACAGAAGCCAATCACTTTGAAGATTCTTCAAAAGAATCCAAAGAAAGCTCAGATCATCTTGACAACCCCACAGAAACTA
AAACCAATTTTGATGAATACGAGTCAGAAGAAACCCAAACTCAAATGGATTCTGGAAATAATGAAACTTCAGAATCTAGC
AATGGCAGTCTAGCAGACAAGTTATTCAAGAAAGCCAGAAAATTAGTTGATGATAAAAGACCTTTCACTCAGCAAAAGAA
TTTAGATGAAGAAATCCAAGAACCGAACGAAGAAGACGATCAAGAAAATAATGGGTATCAAGAAGAAACTCAAATGGACT
TAATTGATGATGAAACTTCTAAAAAAACCCAACAACATTCACCCCAAGATTTATCCAATGAAGAAGCAACAGAAGCCAAT
CACTTTGAAGATTCTTCAAAAGAATCCAAAGAAAGCTCAGATCATCTTGACAACCCCACAGAAACTAAAACCAATTTTGA
TGAATACGAGTCAGAAGAAACAACTAACGATTCTAACGATCAAGAAATTATCAAAGGAAGCAAAAAGAAATACATTATTG
GTGGCATTGTAGTCGCTGTTCTTATCGTGATTATTTTATTTTCTAGAAGCATTTTTCACTACTTCATACCTTTGGAAGAT
AAAAGCTCTCGTTTTAGCAAAGACAGGAATCTTTATGTCAATGATGAAATCCAAATAAGGCAAGAGTATAACCGATTGCT
GAAAGAGCGGAATGAAAAAGGCAATATGATCGATAAGAATCTTTTCCTCAATGACGATCCCAATAGAACCTTATACAACT
ATTTGAATATTGCAGAAATTGAGGACAAAAACCCATTGAGAGCCTTTTATGAATGTATTAGTAATGGTGGCAACTATGAA
GAATGTTTGAAGCTTATCAAAGACAAAAAACTTCAAGATCAAATGAAAAGGACTTTAGAGGCTTATAATGACTGCATCAA
AAATGCCAAAACTGAAGAAGAAAGGATCAAGTGTTTAGATTTGATCAAAGATGAAAACCTGAAAAAAAGCTTATTGAACC
AACAAAAAGTTCAAGTGGCGCTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAACGAAACGAGTGCCTAAAACTCATA
AATGACCCTGAGATTAGAGAGAAATTCCGTAAGGAATTAGGGCTTCAAAAAGAGCTTCAAGAGTATAAGGATTGTATCAA
AAACGCCAAAACAGAAGCTGAGAAAAACGAATGCTTGAAAGGCTTGTCTAAAGAAGCTATAGAAAGATTGAAACAGCAAG
CGCTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAACGAAAAGAGTGCTTGAAAAATATTCCCCAAGACTTGCAAAAA
GAACTACTAGCTGATATGAGCGTCAAGGCTTACAAGGATTGCGTATCAAAAGCTAGGAATGAAAAAGAGAAAAAAGAATG
TGAGAAATTACTCACGCCTGAAGCGAAAAAAAAGTTAGAACAACAGGTTCTAGATTGTTTGAAAAACGCTAAAACTGATG
GAGAACGAAAAAAATGTTTGAAAGATCTCCCTAAAGACTTACAAAGCGATATTTTAGCCAAAGAAAGTCTTAAAGCTTAT
AAAGACTGCGTATCTCAAGCCAAAACTGAAGCTGAGAAAAAAGAATGCGAGAAGTTACTCACGCCTGAAGCGAAAAAACT
TTTAGAAGAAGAAGCCAAAGAGAGCGTTAAGGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGCTGAGAAAAAAG
AATGCGAAAAATTACTCACTCCTGAAGCGAAAAAAAAGTTAGAAGAAGCTAAAAAAAGCGTTAAAGCTTATTTGGATTGC
GTATCTCAAGCCAAAACTGAAGCTGAGAAAAAAGAATGCGAGAAGTTGCTCACGCCTGAAGCGAAAAAACTTTTAGAGCA
ACAAGCGCTAGACTGTTTGAAAAACGCTAAAACTGATGGAGAACGAAAAAAATGTTTGAAAGATCTCCCTAAAGACTTAC
AAAGCGATATTTTAGCCAAAGAAAGTCTTAAAGCTTATAAAGACTGCGTATCTCAAGCCAAAACTGAAGCTGAGAAAAAA
GAATGCGAGAAATTGCTCACCCCTGAAGCGAAAAAACTTTTAGAAGAAGCTAAAGAGAGTCTTAAAGCTTATAAAGACTG
CGTTTCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAGTTACTCACGCCTGAAGCGAAAAAACTTTTAGAAG
AAGAAGCCAAAGAGAGCGTTAAGGCTTATTTGGATTGCGTATCTCAAGCCAAAACTGAAGCTGAGAAAAAAGAATGCGAA
AAATTACTCACTCCTGAAGCGAAAAAAAAGTTAGAAGAAGCTAAAAAAAGCGTTAAAGCTTATTTGGATTGCGTATCTCA
AGCCAAAACTGAAGCTGAGAAAAAAGAATGCGAGAAGTTGCTCACGCCTGAAGCGAAAAAACTTTTAGAGCAACAAGCGC
TAGATTGTTTGAAAAACGCTAAAACCGAAGCTGAGAAAAAAAGGTGTGTCAAAGATCTTCCTAAAGACTTGCAGAAAAAG
GTTTTAGCTAAAGAGAGCCTGAAAGCTTATAAAGACTGCGTTTCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGA
GAAATTACTCACCCCTGAAGCGAAAAAGCTTTTAGAAGAAGCCAAAGAGAGCCTGAAAGCTTATAAAGACTGCGTTTCAA
GAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTACTCACCCCTGAAGCGAAAAAGCTTTTAGAAGAAGCCAAA
GAGAGCGTTAAGGCTTATTTGGACTGCGTTTCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTACTCAC
CCCTGAAGCGAAAAAGCTTTTAGAGCAACAAGCGCTAGATTGTTTGAAAAACGCTAAAACCGAAGCTGAGAAAAAAAGGT
GTGTCAAAGATCTTCCTAAAGACTTGCAGAAAAAGGTTTTAGCCAAAGAGAGCGTTAAGGCTTATTTGGACTGCGTTTCA
AGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTACTCACCCCTGAAGCGAAAAAGCTTTTAGAAGAAGCTAA
AGAGAGTCTTAAAGCTTATAAAGACTGCCTCTCTCAAGCTAGAAATGAAGAAGAAAGGAGAGCTTGTGAGAAATTGCTCA
CCCCTGAAGCGAAAAAACTTTTAGAGCAAGAAGTTAAGAAGAGTGTTAAGGCTTATTTGGACTGCGTATCAAAAGCTAGG
AATGAAAGAGAGAAACAAGAATGCGAGAAATTACTCACCCCTGAAGCGAGAAAATTTTTAGCGAAGCAAGTGCTAAGTTG
TTTGGAAAAAGCTAGAAATGAAGAAGAAAGAAAAGCATGTCTTAAAAATATCCCTAAAGACTTACAGAAAAATGTTTTAG
CTAAAGAGAGTCTTAAAGCTTATAAAGACTGCCTCTCTCAAGCTAGAAATGAAGAAGAAAGAAGAGCTTGCGAGAAATTA
CTCACCCCTGAAGCGAGAAAACTCTTAGAGCAAGAAGTTAAGAAGAGCGTTAAGGCTTATTTGGACTGCGTTTCAAGAGC
TAGGAATGAAAAAGAGAAACAAGAATGCGAGAAATTACTCACCCCTGAAGCGAGGAAATTTTTAGCGAAAGAACTCCAAC
AAAAAGATAAAGCGATCAAAGATTGCTTGAAAAACGCCGATCCTAACGACAGAGCGGCCATTATGAAGTGTTTGGATGGT
TTGAGCGATGAAGAGAAGCTCAAATACCTGCAAGAAGCTAGAGAAAAGGCTGTCTTGGATTGTTTGAAAACGGCTAGGAC
CGATGAAGAAAAAAGGAAATGTCAAAACCTTTATAGCGATTTGATCCAAGAAATCCAAAATAAAAGGACACAAAGCAAAC
AAAATCAATTGAGTAAAACAGAAAGATTGCATCAAGCAAGCGAGTGCTTGGATAACTTAGATGACCCTACTGATCAAGAA
GCCATAGAGCAATGTTTAGAGGGCTTGAGCGATAGTGAAAGGGCGCTAATTCTAGGAATTAAACGACAAGCTGATGAAGT
GGATCTGATTTATAGCGATCTAAGAAACCGCAAAACCTTTGATAACATGGCGGCTAAAGGTTATCCATTGTTGCCAATGG
ATTTCAAAAATGGTGGCGATATTGCCACTATTAACGCCACCAATGTTGATGCGGACAAAATAGCTAGCGATAATCCTATT
TATGCTTCAATAGAGCCTGACATTACCAAGCAATACGAAACAGAAAAAACCATTAAGGATAAGAATTTAGAAGCTAAATT
AGCTAAGGCTTTAGGTGGCAATAAAAAAGATGACGATAAAGAAAAAAGTAAAAAATCCACAGCAGAAGCTAGAGTAGAAA
GCAATAAGATAGACAAAGATGTCGCAGAAACTGCCAAAAATATCAGTGAAATCGCTCTTAAGAACAAAAAAGAAAAGAGT
GGGGAATTTGTAGATGAAAATGGTAATCCCATTGATGACAAAAAGAAAACAGAAACACAAGATGAAACAAGCCCTGTCAA
ACAAGCCTTTATAGGCAAGAGTGATCCCACATTTGTTTTAGCGCAATACACCCCTATTGAAATCACTCTGACTTCTAAAG
TAGATGCCACTCTCACAGGTATAGTGAGTGGGGTTGTAGCCAAAGATGTATGGAACATGAACGGCACTATGATCTTACTA
GACAAAGGCACTAAGGTGTATGGGAATTATCAAAGCGTGAAAGGTGGCACACCCATTATGACACGCTTAATGATAGTCTT
TACTAAAGCCATTACGCCTGATGGTGTGATAATACCTCTAGCAAACGCTCAAGCAGCAGGCATGCTGGGTGAAGCAGGGG
TAGATGGTTATGTGAATAACCACTTTATGAAGCGCATAGGCTTTGCTGTGATAGCAAGCGTGGTTAATAGCTTCTTGCAA
ACTGCGCCTATCATAGCTCTAGATAAACTCATAGGACTTGGCAAAGGTAGAAGTGAAAGGACACCTGAATTTAATTACGC
TTTGGGTCAAGCGATCAATGGTAGTATGCAAAGTTCAGCTCAGATGTCTAATCAAATTCTAGGGCAACTGATGAATATCC
CCCCAAGTTTTTACAAAAATGAGGGCGATAGTATTAAGATTCTCACAATGGACGATATTGATTTTAGTGGCGTGTATGAT
GTTAAAATCACCAACAAATCTGTGGTAGATGAAATTATCAAACAAAGCACTAAAACTTTGTCTAGAGAGCATGAAGAAAT
CACCACAAGCCCCAAAGGTGGCAATTAA

Protein sequence :
MNEENDKLETSKKTQQHSPQDLSNEEATEANHFEDSSKESKESSDHLDNPTETKTNFDEYESEETQTQMDSGNNETSESS
NGSLADKLFKKARKLVDDKRPFTQQKNLDEEIQEPNEEDDQENNGYQEETQMDLIDDETSKKTQQHSPQDLSNEEATEAN
HFEDSSKESKESSDHLDNPTETKTNFDEYESEETTNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYFIPLED
KSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFLNDDPNRTLYNYLNIAEIEDKNPLRAFYECISNGGNYE
ECLKLIKDKKLQDQMKRTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLKLI
NDPEIREKFRKELGLQKELQEYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQALDCLKNAKTDEERKECLKNIPQDLQK
ELLADMSVKAYKDCVSKARNEKEKKECEKLLTPEAKKKLEQQVLDCLKNAKTDGERKKCLKDLPKDLQSDILAKESLKAY
KDCVSQAKTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVKAYLDC
VSQAKTEAEKKECEKLLTPEAKKLLEQQALDCLKNAKTDGERKKCLKDLPKDLQSDILAKESLKAYKDCVSQAKTEAEKK
ECEKLLTPEAKKLLEEAKESLKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECE
KLLTPEAKKKLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEAKKLLEQQALDCLKNAKTEAEKKRCVKDLPKDLQKK
VLAKESLKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEEAK
ESVKAYLDCVSRARNEKEKKECEKLLTPEAKKLLEQQALDCLKNAKTEAEKKRCVKDLPKDLQKKVLAKESVKAYLDCVS
RARNEKEKKECEKLLTPEAKKLLEEAKESLKAYKDCLSQARNEEERRACEKLLTPEAKKLLEQEVKKSVKAYLDCVSKAR
NEREKQECEKLLTPEARKFLAKQVLSCLEKARNEEERKACLKNIPKDLQKNVLAKESLKAYKDCLSQARNEEERRACEKL
LTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLAKELQQKDKAIKDCLKNADPNDRAAIMKCLDG
LSDEEKLKYLQEAREKAVLDCLKTARTDEEKRKCQNLYSDLIQEIQNKRTQSKQNQLSKTERLHQASECLDNLDDPTDQE
AIEQCLEGLSDSERALILGIKRQADEVDLIYSDLRNRKTFDNMAAKGYPLLPMDFKNGGDIATINATNVDADKIASDNPI
YASIEPDITKQYETEKTIKDKNLEAKLAKALGGNKKDDDKEKSKKSTAEARVESNKIDKDVAETAKNISEIALKNKKEKS
GEFVDENGNPIDDKKKTETQDETSPVKQAFIGKSDPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILL
DKGTKVYGNYQSVKGGTPIMTRLMIVFTKAITPDGVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQ
TAPIIALDKLIGLGKGRSERTPEFNYALGQAINGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYD
VKITNKSVVDEIIKQSTKTLSREHEEITTSPKGGN