PAI Gene Information


Name : HP0527
Accession : BAD13860.1
PAI name : cag PAI
PAI accession : AB120419
Strain : Helicobacter pylori 2017
Virulence or Resistance: Virulence
Product : cag pathogenicity island protein
Function : -
Note : similar to virB10, H.pylori 26695 gene HP0527:cag7, J99 gene JHP0476, NCTC11638 gene ORF13andORF14:cag-Y
Homologs in the searched genomes :   29 hits    ( 29 protein-level )  
Publication :
    -Azuma,T., Yamakawa,A. and Yamazaki,S., "Direct Submission", Submitted (12-SEP-2003) Takeshi Azuma, University of Fukui Faculty of Medical Sciences, General Medicine Second Department of Internal Medicine; Shimoaizuki 23-3, Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan (E-mail:azuma@fmsrsa.fukui-med.ac.jp, Tel:8.

    -Azuma,T., Yamakawa,A., Yamazaki,S., Ohtani,M., Ito,Y., Muramatsu,A., Suto,H., Yamazaki,Y., Keida,Y., Higashi,H. and Hatakeyama,M., "Distinct diversity of the cag pathogenicity island among Helicobacter pylori strains in Japan", J. Clin. Microbiol. 42 (6), 2508-2517 (2004) PUBMED 15184428.


DNA sequence :
ATGAATGAAGAAAACGATAAACTTGAAACTTCTCAAAAAACCCAACAACATTCACCCCAAGATTTATCCAATGAAGAAAC
AACAGAAGCCAATCGCTTTGAAGATTCTTCAAAAGAATCCGAAGAAAGCTCAGATCATCTTGACAACCCCACAGAAACTA
AAACCAATTTTGATGAATACGAGTCAGAAGAAACCCAAACTCAAATGGATTCTGGAGGTAATGAAACTTCAGAATCTAGC
AATGGCAGTCTAGCAGACAAGTTATTCAAAAAAGCTAGAAAATTAGTTGATAATAAAAGACCTTTCACTCAGCAAAAGAA
TTTAGATGAAGAAACCCAAGAACCGAACGAAGAAGACGATCAAGAAAATAATAGGTATCAAGAAGAAACTCAAATGGACT
TAATTGATGATGAAACTTCTAAAAAAACCCAACAACATTCACCCCAAGATTTATCCAATGAAGAAGCGACAGAAGCCAAT
CACTTTGAAGATTCTTCAAAAGAATCCCAAGAAAGCTCAGAACATCATCTTGACAACCCTACAGAAACTAAAACCAATTT
TGATGAATACGAGTCAGAAGAAACCCAAACTCAAATGGATTCTGGAGGTAATGAAACTTCAGAATCTAGCAATGGCAGTC
TAGCAGACAAGTTATTCAAAAAAGCTAGAAAATTAGTTGATAATAAAAGACCTTTCACTCAGCAAAAGAATTTAGATGAA
GAAACCCAAGAACCGAACGAAGAAGACGATCAAGAAAATAATAGGGATCAAGAAGAAACTCAAATGGACTTAATTGATGA
TGAAACTTCTAAAAAAACCCAACAACATTCACCCCAAGATTTATCCAATGAAGAAGCGACAGAAGCCAATCACTTTGAAG
ATTCTTCAAAAGAATCCCAAGAAAGCTCAGAACATCATCTTGACAACCCTACAGAAACTAAAACCAATTTTGATGAATAC
GAGTCAGAAGAAATAACTAACGATTCTAACGATCAAGAGATTATCAAAGGAAGCAAAAAGAAATACATTATTGGTGGCAT
TGTAGTCGCTGTTCTTATCGTGATTATTTTATTTTCTAGAAGCATTTTTCACTACTTCATACCTTTGGAAGATAAAAGCT
CTCGTTTTAGCAAAGACAGGAATCTTTATGTCAATGATGAAATCCAAATAAGGCAAGAGTATAACCGATTGCTGAAAGAA
CGGAATGAAAAAGGCAATATGATCGATAAGAATCTTTTCTTCAATGACGATCCCAATAGAACCTTATACAACTATTTGAA
TATTGCAGAAATTGAGGACAAAAACCCATTGAGAGCCTTTTATGAATGTATTAGCAATGGTGGCAACTATGAAGAATGTT
TGAAGCTTATCAAAGACAAAAAACTTCAAGATCAAATGAAAAAGACTTTAGAGGCTTATAATGACTGCATCAAAAATGCC
AAAACTGAAGAAGAAAGAATCAAGTGTTTAGATTTAATCAAAGATGAAAACCTGAAAAAAAGCTTACTGAACCAACAAAA
AGTTCAAGTGGCGCTAGATTGTTTGAAAAACGCTAAAACCGATGAAGAACGAAACGAGTGCCTAAAACTCATAAATGACC
CTGAGATTAGAGAGAAATTCCGTAAGGAATTAGGGCTTCAAAAAGAGCTTCAAGAGTATAAGGATTGTATCAAAAACGCC
AAAACAGAAGCTGAGAAAAACGAATGTTTGAAAGGCTTGTCTAAAGAAGCTATAGAAAGATTGAAACAGCAAGCACTAGA
TTGTTTGAAAAACGCTAAAACCGATGAAGAACGAAACGAGTGCTTGAAAAATATTCCCCAAGACTTACAAAAAGAACTAC
TAGCTGATATGAGCGTCAAGGCTTACAAGGATTGCGTATCAAAAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAA
TTACTCACTCCTGAAGCGAAAAAAAAGTTAGAACAACAGGTTCTAGATTGTTTGAAAAACGCTAAAACTGATGAAGAACG
AAAAAAGTGTTTGAAAGATCTCCCTAAAGACTTACAAAGCGATATTTTAGCTAAAGAGAGCCTGAAAGCTTATAAAGACT
GCGTGTCTCAAGCCAAAACTGAAGCTGAGAAAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAACTTTTAGAA
GAAGAAGCCAAAGAGAGCGTTAAGGCTTATTTGGACTGCGTATCTCAAGCCAAAACTGAAGTTGAGAAAAAAGAATGCGA
GAAATTACTCACGCCTGAAGCGAAAAAAAAGTTAGAAGAAGCTAAAAAAAGCGTTAAGGCTTATTTGGACTGCGTATCTC
AAGCCAAAACTGAAGCTGAGAAAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAGCTTTTAGAGCAACAAGCG
CTAGATTGTTTGAAAAACGCTAAAACTGATGAAGAACGAAAAAAGTGTTTGAAAGATCTCCCTAAAGACTTGCAGAAAAA
GGTTTTAGCTAAAGAGAGCGTTAAAGCTTACTTGGATTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCG
AGAAATTACTCACGCCTGAAGCGAAAAAGCTTTTAGAAGAAGCTAAAGAGAGCCTGAAAGCTTATAAAGACTGCGTGTCT
CAAGCCAAAACTGAAGCTGAGAAAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAACTTTTAGAAGAAGAAGC
CAAAGAGAGCGTTAAGGCTTATTTGGACTGCGTATCTCAAGCCAAAACTGAAGCTGAGAAAAAAGAATGCGAGAAATTAC
TCACGCCTGAAGCGAAAAAAAAGTTAGAAGAAGCTAAAAAAAGCGTTAAGGCTTATTTGGACTGCGTATCTCAAGCCAAA
ACTGAAGCTGAGAAAAAAGAATGCGAGAAATTACTCACGCCTGAAGCGAAAAAGCTTTTAGAGCAACAAGCGCTAGATTG
TTTGAAAAACGCTAAAACTGATGAAGAACGAAAAAAGTGTTTGAAAGATCTCCCTAAAGACTTGCAGAAAAAGGTTTTAG
CTAAAGAGAGCGTTAAAGCTTACTTGGATTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTA
CTCACGCCTGAAGCGAAAAAGCTTTTAGAAGAAGCTAAAGAGAGCCTGAAAGCTTATAAAGACTGCGTGTCTCAAGCCAA
AACTGAAGCTGAGAAAAAAGAATGCGAGAAATTGCTCACCCCTGAAGCGAAAAAGCTTTTAGAAGAAGCTAAAGAGAGCC
TGAAAGCTTATAAAGACTGCGTTTCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTGCTCACCCCTGAA
GCGAAAAAGCTTTTAGAAGAAGCTAAAGAGAGCCTGAAAGCTTATAAAGACTGCGTTTCAAGAGCTAGGAATGAAAAAGA
GAAAAAAGAATGCGAGAAATTGCTCACCCCTGAAGCGAAAAAGCTTTTAGAAGAAGCTAAAGAGAGCCTGAAAGCTTATA
AAGACTGCGTTTCAAGAGCTAGGAATGAAAAAGAGAAAAAAGAATGCGAGAAATTACTCACCCCTGAAGCAAAAAAGCTT
TTAGAGCAACAAGCGCTAGATTGTTTGAAAAACGCTAAAACCGAAGCTGAGAAAAAGAGGTGTGTCAAAGATCTCCCTAA
AGACTTGCAGAAAAAGGTTTTAGCCAAAGAGAGCGTTAAGGCTTATTTGGACTGCGTTTCAAAAGCTAGGAATGAAAAAG
AAAGAAAAGCTTGCGAGAAACTACTCACCCCTGAAGCGAAAAAACTTTTAGAAGAAGCCAAAGAGAGTCTTAAAGCTTAT
AAAGACTGCCTCTCTCAAGCTAGAAATGAAGAAGAAAGGAGAGCTTGCGAGAAATTGCTCACCCCTGAAGCGAGGAAACT
CTTAGAGCAAGAAGTTAAGAAGAGCGTTAAGGCTTATTTGGATTGCGTATCAAGAGCTAGGAATGAAAAAGAGAAACAAG
AATGCGAGAAATTGCTCACGCCTGAAGCGAGAAAATTCTTAGCGAAGCAAGCGCTAAGTTGTTTGGAAAAAGCTGGAAAT
GAAGAAGAAAGAAAAGCATGTCTTAAAAATCTCCCTAAAGACTTACAGGAAAATGTTTTAGCTAAAGAGAGTCTTAAAGC
TTATAAAGACTGCCTCTCTCAAGCTAGAAATGAAGAAGAAAGGAGAGCTTGCGAGAAATTGCTCACCCCTGAAGCGAGGA
AACTCTTAGAGCAAGAAGTTAAGAAGAGCGTTAAGGCTTATTTGGACTGCGTTTCAAGAGCTAGAAATGAAAAAGAGAAA
CAAGAATGCGAGAAATTACTCACCCCTGAAGCGAGAAAATTTTTAGCGAAAGAACTCCAACAAAAAGATAAAGCGATCAA
AGATTGCTTGAAAAACGCCGATCCTAACGACAGAGTGGCTATTATGAAGTGTTTGGATGGTTTGAGCGATGAAGAGAAGC
TCAAATACCTGCAAGAAGCTAGAGAAAAGGCTGTCTTGGATTGTTTGAAAACGGCTAGGACCGATGAAGAAAAAAGGAAA
TGTCAAAACCTTTATAGCGATTTGATCCAAGAAATCCAAAATAAAAGGACACAAAATAAACAAAATCAATTGAGTAAAAC
AGAAAGATTGCATCAAGCAAGCGAGTGCTTGGATAACTTAGATGACCCTACTGATCAGGAAGCCATAGAGCAATGTTTAG
AGGGCTTGAGCGATAGTGAAAGGGCGCTAATTCTAGGAATTAAACGACAAGCTGATGAAGTGGATCTGATTTATAGCGAT
CTAAGAAACCGCAAAACCTTTGATAACATGGCGGCTAAAGGTTATCCATTGTTGCCAATGGATTTCAAAAATGGTGGCGA
TATTGCCACTATTAACGCCACTAATGTTGATGCGGACAAAATAGCTAGCGATAATCCTATTTATGCTTCCATAGAGCCTG
ATATTACTAAGCAATACGAAACAGAAAAAACCATTAAGGATAAGAATTTAGAAGCTAAATTAGCTAAGGCTTTAGGTGGC
AATAAAAAAGATGACGATAAAGAAAAAAGTAAAAAATCCACAGCAGAAGCTAGAGTAGAAAGCAATAAGATAGACAAAGA
TGTCGCAGAAACTGCCAAAAATATCAGTGAAATCGCTCTTAAGAACAAAAAAGAAAAGAGTGGGGAATTTGTAGATGAAA
ATGGTAATCCCATTGATGACAAAAAGAAAACAGAAACACAAGATGAAACAAGCCCTGTCAAACAAGCCTTTATAGGCAAG
AGTGATCCCACATTTGTTTTAGCGCAATACACCCCTATTGAAATCACTCTGACTTCTAAAGTAGATGCCACTCTCACAGG
TATAGTGAGTGGGGTTGTAGCCAAAGATGTATGGAACATGAACGGCACTATGATCTTACTAGACAAAGGCACTAAGGTGT
ATGGGAATTACCAAAGCGTGAAAGGTGGCACACCCATTATGACACGCTTAATGATAGTCTTTACTAAAGCCATTACGCCT
GATGGTGTGATAATACCTCTAGCAAACGCTCAAGCAGCAGGCATGTTGGGTGAAGCAGGGGTAGATGGCTATGTGAATAA
CCACTTCATGAAGCGCATAGGCTTTGCTGTGATAGCAAGCGTGGTTAATAGCTTCTTGCAAACTGCGCCTATCATAGCTC
TAGATAAACTCATAGGCCTTGGCAAAGGTAGAAGTGAAAGGACACCTGAATTTAATTACGCTTTGGGTCAAGCTATCAAT
GGTAGTATGCAAAGTTCAGCTCAGATGTCTAATCAAATTCTAGGGCAACTGATGAATATCCCCCCAAGTTTTTACAAAAA
TGAGGGCGATAGTATTAAGATTCTCACAATGGACGATATTGATTTTAGTGGCGTGTATGATGTTAAAATCACCAACAAAT
CTGTGGTAGATGAAATTATCAAACAAAGCACTAAAACTTTGTCTAGAGAGCATGAAGAAATCACCACAAGTCCCAAAGGT
GGCAATTAA

Protein sequence :
MNEENDKLETSQKTQQHSPQDLSNEETTEANRFEDSSKESEESSDHLDNPTETKTNFDEYESEETQTQMDSGGNETSESS
NGSLADKLFKKARKLVDNKRPFTQQKNLDEETQEPNEEDDQENNRYQEETQMDLIDDETSKKTQQHSPQDLSNEEATEAN
HFEDSSKESQESSEHHLDNPTETKTNFDEYESEETQTQMDSGGNETSESSNGSLADKLFKKARKLVDNKRPFTQQKNLDE
ETQEPNEEDDQENNRDQEETQMDLIDDETSKKTQQHSPQDLSNEEATEANHFEDSSKESQESSEHHLDNPTETKTNFDEY
ESEEITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYFIPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKE
RNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNA
KTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELGLQKELQEYKDCIKNA
KTEAEKNECLKGLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDLQKELLADMSVKAYKDCVSKARNEKEKKECEK
LLTPEAKKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAKESLKAYKDCVSQAKTEAEKKECEKLLTPEAKKLLE
EEAKESVKAYLDCVSQAKTEVEKKECEKLLTPEAKKKLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEAKKLLEQQA
LDCLKNAKTDEERKKCLKDLPKDLQKKVLAKESVKAYLDCVSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYKDCVS
QAKTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVKAYLDCVSQAK
TEAEKKECEKLLTPEAKKLLEQQALDCLKNAKTDEERKKCLKDLPKDLQKKVLAKESVKAYLDCVSRARNEKEKKECEKL
LTPEAKKLLEEAKESLKAYKDCVSQAKTEAEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSRARNEKEKKECEKLLTPE
AKKLLEEAKESLKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSRARNEKEKKECEKLLTPEAKKL
LEQQALDCLKNAKTEAEKKRCVKDLPKDLQKKVLAKESVKAYLDCVSKARNEKERKACEKLLTPEAKKLLEEAKESLKAY
KDCLSQARNEEERRACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLAKQALSCLEKAGN
EEERKACLKNLPKDLQENVLAKESLKAYKDCLSQARNEEERRACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEK
QECEKLLTPEARKFLAKELQQKDKAIKDCLKNADPNDRVAIMKCLDGLSDEEKLKYLQEAREKAVLDCLKTARTDEEKRK
CQNLYSDLIQEIQNKRTQNKQNQLSKTERLHQASECLDNLDDPTDQEAIEQCLEGLSDSERALILGIKRQADEVDLIYSD
LRNRKTFDNMAAKGYPLLPMDFKNGGDIATINATNVDADKIASDNPIYASIEPDITKQYETEKTIKDKNLEAKLAKALGG
NKKDDDKEKSKKSTAEARVESNKIDKDVAETAKNISEIALKNKKEKSGEFVDENGNPIDDKKKTETQDETSPVKQAFIGK
SDPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQSVKGGTPIMTRLMIVFTKAITP
DGVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTAPIIALDKLIGLGKGRSERTPEFNYALGQAIN
GSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKITNKSVVDEIIKQSTKTLSREHEEITTSPKG
GN